Zobrazeno 1 - 10
of 53
pro vyhledávání: '"J. N. M. Heersche"'
Publikováno v:
Journal of Bone and Mineral Research. 5:S115-S120
It is not clear to what extent the increased bone mass observed in vertebral trabecular bone of fluoride-treated mammals is a consequence of effects of fluoride on the number and activity of osteoclasts or of osteoblasts. In the present communication
Publikováno v:
Bone. 36:173-183
Experiments with rats flown in space or hind limb unloaded (HU) indicate that bone loss in both conditions is associated with a decrease in bone volume and osteoblast surface in cancellous and cortical bone. We hypothesize that the decrease in osteob
Publikováno v:
Osteoporosis International. 13:235-240
Studies in vitro and in vivo have shown that glucocorticoids and sex steroids play an important role in bone physiology and pathophysiology. In this study we investigated glucocorticoid and sex steroid conversion in osteoblasts derived from lumbar ve
Publikováno v:
Bone. 28:187-194
Diseases exhibiting excessive bone loss are often characterized by an increase in the size and number of osteoclasts in affected areas, suggesting that osteoclast size is associated with increased resorptive activity or efficiency. Because osteoclast
Publikováno v:
Bone. 23:119-125
Osteoprogenitors present in cell populations derived from fetal or newborn rat and mouse calvaria differentiate in long term culture and form osteoblastic bone-forming colonies (bone nodules). Previous reports have indicated considerable differences
Publikováno v:
Osteoporosis International. 7:323-330
We have shown previously that progesterone (Prog) and dexamethasone (Dex) stimulate osteoprogenitor proliferation and differentiation in cell populations derived from adult rat vertebrae and in primary cultures of fetal rat calvariae. In these two in
Publikováno v:
Bone. 16:545-549
We investigated the role of 3,5,3′-tri-iodothyronine (T3) in regulating differentiation of osteoprogenitor cells and also studied the effects of the glucocorticoid hormone dexamethasone (Dex) on the T3-induced effects on osteoprogenitor populations
Autor:
Ori D. Rotstein, Sergio Grinstein, Tommy Nordström, Guy F. Brisseau, Satish Asotra, J. N. M. Heersche, Robert Romanek, Morris F. Manolson
Publikováno v:
Journal of Biological Chemistry. 270:2203-2212
Osteoclasts resorb bone by secreting protons into an extracellular resorption zone through vacuolar-type proton pumps located in the ruffled border. The present study was undertaken to evaluate whether proton pumps also contribute to intracellular pH
Publikováno v:
Endocrinology. 134:2221-2229
Progenitor cells for several mesenchymally derived cell types exist within freshly isolated fetal rat calvaria (RC) cell populations. We have characterized the effects of 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3] on the differentiation of adipocytes fr