Zobrazeno 1 - 10
of 22
pro vyhledávání: '"J. N. Lindon"'
Publikováno v:
Biochemistry. 29:3277-3286
The human fibrinogen gamma-chain, C-terminal fragment, residues 385-411, i.e., KIIPFNRLTIGEGQQHHLGGAKQAGDV, contains two biologically important functional domains: (1) fibrinogen gamma-chain polymerization center and (2) platelet receptor recognition
Publikováno v:
The International journal of artificial organs. 16(5)
An alternative graft is needed for coronary bypass operations in patients lacking suitable autologous vessels. We therefore studied Denaflex, a biologic graft, in a dog ex-vivo shunt model to determine whether heparin treatment makes this graft less
Publikováno v:
ASAIO transactions. 36(3)
The authors describe a technique for rapid, on-line, precardiopulmonary bypass separation and collection of 10-20% of a patient's platelets for storage and postoperative reinfusion. In a three stage process, blood is diverted through a hollow fiber h
Publikováno v:
Biochemistry. 29(13)
The human fibrinogen gamma-chain, C-terminal fragment, residues 385-411, i.e., KIIPFNRLTIGEGQQHHLGGAKQAGDV, contains two biologically important functional domains: (1) fibrinogen gamma-chain polymerization center and (2) platelet receptor recognition
Does the conformation of adsorbed fibrinogen dictate platelet interactions with artificial surfaces?
Publikováno v:
Blood. 68:355-362
Platelet activation by polymer surfaces is thought to require preliminary adsorption of fibrinogen and perhaps changes in fibrinogen conformation. We measured fibrinogen adsorption by a series of polymers by two methods, using either 125I-labeled fib
Autor:
Marek Kloczewiak, J A Ware, MA Smith, Gerald McManama, Edward W. Merrill, E W Salzman, J N Lindon, Jacek Hawiger
Publikováno v:
Blood. 68:363-371
There is evidence that platelet interactions with artificial surfaces are mediated by plasma proteins, especially fibrinogen, adsorbed on the surfaces. Multiple site interactions between fibrinogen molecules adsorbed in high concentration and recepto
Autor:
G, McManama, J N, Lindon, M, Kloczewiak, M A, Smith, J A, Ware, J, Hawiger, E W, Merrill, E W, Salzman
Publikováno v:
Blood. 68:363-371
There is evidence that platelet interactions with artificial surfaces are mediated by plasma proteins, especially fibrinogen, adsorbed on the surfaces. Multiple site interactions between fibrinogen molecules adsorbed in high concentration and recepto
Does the conformation of adsorbed fibrinogen dictate platelet interactions with artificial surfaces?
Publikováno v:
Blood. 68:355-362
Platelet activation by polymer surfaces is thought to require preliminary adsorption of fibrinogen and perhaps changes in fibrinogen conformation. We measured fibrinogen adsorption by a series of polymers by two methods, using either 125I-labeled fib
Publikováno v:
Thrombosis et diathesis haemorrhagica. 34(2)
Publikováno v:
XIth International Congress on Thrombosis and Haemostasis.
Adsorption of fibrinogen (Fg) appears to be an important precusor of platelet reactivity with artificial surfaces. We have reported that, contrary to the prevailing view, platelet reactivity is less well correlated with the total concentration of ads