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pro vyhledávání: '"J. N. Howe"'
Autor:
David Bom, Thomas G. Burke, Robert L. Bevins, J. N. Howe, Stefan Kruszewski, Lori J. Latus, Stephen G. Zimmer, AL Bingcang, Junhong Zhang, Dennis P. Curran
Publikováno v:
Journal of Controlled Release. 74:325-333
The novel silatecan 7-t-butyldimethylsilyl-10-hydroxycamptothecin (DB-67) is 25- to 50-times more lipophilic than camptothecin and readily incorporates into lipid bilayers. Using the method of fluorescence anisotropy titration, we determined that DB-