Zobrazeno 1 - 10
of 290
pro vyhledávání: '"J. Mobley"'
Autor:
Priya Mittal, Jacquelyn A. Myers, Raymond D. Carter, Sandi Radko-Juettner, Hayden A. Malone, Wojciech Rosikiewicz, Alexis N. Robertson, Zhexin Zhu, Ishwarya V. Narayanan, Baranda S. Hansen, Meadow Parrish, Natarajan V. Bhanu, Robert J. Mobley, Jerold E. Rehg, Beisi Xu, Yiannis Drosos, Shondra M. Pruett-Miller, Mats Ljungman, Benjamin A. Garcia, Gang Wu, Janet F. Partridge, Charles W. M. Roberts
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Genes encoding subunits of SWI/SNF (BAF) chromatin remodeling complexes are mutated in nearly 25% of cancers. To gain insight into the mechanisms by which SWI/SNF mutations drive cancer, we contributed ten rhabdoid tumor (RT) cell lines muta
Externí odkaz:
https://doaj.org/article/fb1fbd9e73e346ad922fc3783cc2f771
Autor:
Kashi Raj Bhattarai, Robert J. Mobley, Kelly R. Barnett, Daniel C. Ferguson, Baranda S. Hansen, Jonathan D. Diedrich, Brennan P. Bergeron, Satoshi Yoshimura, Wenjian Yang, Kristine R. Crews, Christopher S. Manring, Elias Jabbour, Elisabeth Paietta, Mark R. Litzow, Steven M. Kornblau, Wendy Stock, Hiroto Inaba, Sima Jeha, Ching-Hon Pui, Cheng Cheng, Shondra M. Pruett-Miller, Mary V. Relling, Jun J. Yang, William E. Evans, Daniel Savic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Defining genetic factors impacting chemotherapy failure can help to better predict response and identify drug resistance mechanisms. However, there is limited understanding of the contribution of inherited noncoding genetic variation on inte
Externí odkaz:
https://doaj.org/article/50de02b6348449e7a1264f8dc70d8016
Autor:
Robert J. Mobley, Deepthi Raghu, Lauren D. Duke, Kayley Abell-Hart, Jon S. Zawistowski, Kyla Lutz, Shawn M. Gomez, Sujoy Roy, Ramin Homayouni, Gary L. Johnson, Amy N. Abell
Publikováno v:
Cell Reports, Vol 18, Iss 10, Pp 2387-2400 (2017)
The first epithelial-to-mesenchymal transition (EMT) occurs in trophoblast stem (TS) cells during implantation. Inactivation of the serine/threonine kinase MAP3K4 in TS cells (TSKI4 cells) induces an intermediate state of EMT, where cells retain stem
Externí odkaz:
https://doaj.org/article/c291185a476a427d8daabaff777c0e5d
Publikováno v:
Cell Reports, Vol 26, Iss 13, Pp 3684-3697.e7 (2019)
Summary: O-GalNAc glycosylation is initiated in the Golgi by glycosyltransferases called GALNTs. Proteomic screens identified >600 O-GalNAc-modified proteins, but the biological relevance of these modifications has been difficult to determine. We hav
Externí odkaz:
https://doaj.org/article/127e4a1b18fc4ba7a6a83ff344a2d6ca
Akademický článek
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Autor:
Kelly R. Barnett, Robert J. Mobley, Jonathan D. Diedrich, Brennan P. Bergeron, Kashi Raj Bhattarai, Wenjian Yang, Kristine R. Crews, Christopher S. Manring, Elias Jabbour, Elisabeth Paietta, Mark R. Litzow, Steven M. Kornblau, Wendy Stock, Hiroto Inaba, Sima Jeha, Ching-Hon Pui, Charles G. Mullighan, Mary V. Relling, Jun J. Yang, William E. Evans, Daniel Savic
Publikováno v:
bioRxiv
SUMMARYB-cell lineage acute lymphoblastic leukemia (B-ALL) is comprised of diverse molecular subtypes and while transcriptional and DNA methylation profiling of B-ALL subtypes has been extensively examined, the accompanying chromatin landscape is not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f213e6ffa6f24db72b8d17fd9ae7a235
https://doi.org/10.1101/2023.02.14.528493
https://doi.org/10.1101/2023.02.14.528493
Autor:
Kashi Raj Bhattarai, Robert J. Mobley, Kelly R. Barnett, Daniel C. Ferguson, Baranda S. Hansen, Jonathan D. Diedrich, Brennan P. Bergeron, Wenjian Yang, Kristine R. Crews, Christopher S. Manring, Elias Jabbour, Elisabeth Paietta, Mark R. Litzow, Steven M. Kornblau, Wendy Stock, Hiroto Inaba, Sima Jeha, Ching-Hon Pui, Cheng Cheng, Shondra M. Pruett-Miller, Mary V. Relling, Jun J. Yang, William E. Evans, Daniel Savic
Publikováno v:
medRxiv
Although acute lymphoblastic leukemia (ALL) is the most common childhood cancer, there is limited understanding of the contribution of inherited genetic variation on inter-individual differences in chemotherapy response. Defining genetic factors impa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e09ca0863c0f8c1cf5d3d98ce30a630
https://europepmc.org/articles/PMC9934807/
https://europepmc.org/articles/PMC9934807/
Autor:
Brennan P. Bergeron, Kelly R. Barnett, Kashi Raj Bhattarai, Robert J. Mobley, Baranda S. Hansen, Anthony Brown, Kiran Kodali, Anthony A. High, Sima Jeha, Ching-Hon Pui, Junmin Peng, Shondra M. Pruett-Miller, Daniel Savic
Publikováno v:
bioRxiv
Glucocorticoids (GCs; i.e., steroids) are important chemotherapeutic agents in the treatment of B-cell precursor acute lymphoblastic leukemia (B-ALL) andde novoGC resistance predicts relapse and poor clinical outcome in patients. Glucocorticoids indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5441e64db07beb3ceef9c0ec07849af7
https://europepmc.org/articles/PMC9882342/
https://europepmc.org/articles/PMC9882342/
Autor:
Michael J. Mobley
Publikováno v:
Optical Modeling and Performance Predictions XII.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb54cbdc302f3e3c0a1e25b252275f89
https://doi.org/10.1117/12.2632177
https://doi.org/10.1117/12.2632177
Akademický článek
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