Zobrazeno 1 - 10
of 142
pro vyhledávání: '"J. Mitton"'
Publikováno v:
SynOpen, Vol 06, Iss 02, Pp 110-131 (2022)
The synthesis of aromatic heterocycles has attracted substantial attention due to the abundance of these heterocycles in drug molecules, natural products, and other compounds of biological interest. Accordingly, there is a demand for straightforward
Externí odkaz:
https://doaj.org/article/fe192d89bff14a64b7b754f4d163607a
Autor:
Anna Chen, Sheri Dellos-Nolan, Yanran Lu, Jason S. West, Daniel J. Wozniak, Mark J. Mitton-Fry
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT The development of novel treatments for Staphylococcus aureus infections remains a high priority worldwide. We previously reported compounds 0147 and 0186, novel bacterial topoisomerase inhibitors (NBTIs) with potent antibacterial activity a
Externí odkaz:
https://doaj.org/article/d5af706ff5d24891bc199c195e179153
Publikováno v:
Otology & Neurotology. 44:e328-e332
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::475715d6026a29db5f5665a93388a3aa
https://doi.org/10.1097/mao.0000000000003869
https://doi.org/10.1097/mao.0000000000003869
Autor:
Tanner J. Mitton, Kristen L. Yancey, Brandon Isaacson, Walter Kutz, Johanna Whitson, Jacob B. Hunter
Publikováno v:
Otolaryngology–Head and Neck Surgery. 168:1156-1163
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79fc34c0685e7505052635ff4a327525
https://doi.org/10.1002/ohn.162
https://doi.org/10.1002/ohn.162
Publikováno v:
Academic Medicine. 98:448-454
Concerns regarding interview hoarding in the Match process have led to calls for a cap on the number of interviews an applicant can accept. However, no study has examined the effects of interview caps on applicants or a specialty. The authors created
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac4aeeddf74b405cc691b3d6d4b68d8
https://doi.org/10.1097/acm.0000000000005122
https://doi.org/10.1097/acm.0000000000005122
Autor:
Yanran Lu, Chelsea A. Mann, Sheri Nolan, Jessica A. Collins, Elizabeth Parker, Jonathan Papa, Sandip Vibhute, Seyedehameneh Jahanbakhsh, Mary Thwaites, David Hufnagel, Manzour H. Hazbón, Jane Moreno, Timothy T. Stedman, Thomas Wittum, Daniel J. Wozniak, Neil Osheroff, Jack C. Yalowich, Mark J. Mitton-Fry
Publikováno v:
ACS Med Chem Lett
[Image: see text] Antibacterial resistance continues its devastation of available therapies. Novel bacterial topoisomerase inhibitors (NBTIs) offer one solution to this critical issue. Two series of amine NBTIs bearing tricyclic DNA-binding moieties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::934860af063cf23e9ef1477c45523de7
https://doi.org/10.1021/acsmedchemlett.2c00111
https://doi.org/10.1021/acsmedchemlett.2c00111
Autor:
Linsen Li, Steffen Lindert, Yanran Lu, Anna Chen, Jason E. Cummings, Chelsea A Mann, Sandip Vibhute, Brieanna Roth, Anthony English, Sheri Nolan, Mark J. Mitton-Fry, Daniel J. Wozniak, Steven C Ratigan, Richard A. Slayden, Jack C. Yalowich, Bryan Koci, Antony A. Okumu, Jonathan L. Papa, Craig A. McElroy, Justin T Seffernick, Leonard R Duncan
Publikováno v:
Journal of Medicinal Chemistry. 64:15214-15249
Novel bacterial topoisomerase inhibitors (NBTIs) are among the most promising new antibiotics in preclinical/clinical development. We previously reported dioxane-linked NBTIs with potent antistaphylococcal activity and reduced hERG inhibition, a key
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3892c880ddb3b3758eba4c921a02b47
https://doi.org/10.1021/acs.jmedchem.1c01250
https://doi.org/10.1021/acs.jmedchem.1c01250
Autor:
Tanner J. Mitton, Daniel E. Killeen, Zoha K. Momin, Jacob B. Hunter, Brandon Isaacson, Kenneth Lee, Joe Walter Kutz
Publikováno v:
Otologyneurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 43(10)
To compare closure rates and hearing outcomes of microscopic and endoscopic tympanoplasty in pediatric patients.Retrospective chart review.Tertiary university medical center.Pediatric patients who underwent tympanoplasty surgery by a fellowship-train
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb0f0c778f81cbceebeb3428cee3e173
https://pubmed.ncbi.nlm.nih.gov/36166975
https://pubmed.ncbi.nlm.nih.gov/36166975
Autor:
Josh Powell, Justin T Seffernick, Jonathan L. Papa, Daniel J. Wozniak, Jack C. Yalowich, Sheri Nolan, Mark J. Mitton-Fry, Yanran Lu, Nicholas Shkolnikov, Steffen Lindert, Anthony English
Publikováno v:
ACS Medicinal Chemistry Letters. 11:2446-2454
In recent years, novel bacterial topoisomerase inhibitors (NBTIs) have been developed as future antibacterials for treating multidrug-resistant bacterial infections. A series of dioxane-linked NBTIs with an amide moiety has been synthesized and evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f8cd7c2746ada046397671d884e9eca
https://doi.org/10.1021/acsmedchemlett.0c00428
https://doi.org/10.1021/acsmedchemlett.0c00428
Autor:
Yanran, Lu, Sandip, Vibhute, Linsen, Li, Antony, Okumu, Steven C, Ratigan, Sheri, Nolan, Jonathan L, Papa, Chelsea A, Mann, Anthony, English, Anna, Chen, Justin T, Seffernick, Bryan, Koci, Leonard R, Duncan, Brieanna, Roth, Jason E, Cummings, Richard A, Slayden, Steffen, Lindert, Craig A, McElroy, Daniel J, Wozniak, Jack, Yalowich, Mark J, Mitton-Fry
Publikováno v:
Journal of medicinal chemistry. 64(20)
Novel bacterial topoisomerase inhibitors (NBTIs) are among the most promising new antibiotics in preclinical/clinical development. We previously reported dioxane-linked NBTIs with potent antistaphylococcal activity and reduced hERG inhibition, a key
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc8f7442e2cb53241c3d17ad1ee5eb4c
https://pubmed.ncbi.nlm.nih.gov/34614347
https://pubmed.ncbi.nlm.nih.gov/34614347