Zobrazeno 1 - 10
of 471
pro vyhledávání: '"J. Millen"'
Autor:
Lynda M. McSorley, Mehala Tharmabala, Fathiya Al Rahbi, Fergus Keane, Denis Evoy, James G. Geraghty, Jane Rothwell, Damian P. McCartan, Megan Greally, Miriam O’Connor, Deirdre O’Mahony, Maccon Keane, Michael John Kennedy, Seamus O’Reilly, Steve J. Millen, John P. Crown, Catherine M. Kelly, Ruth S. Prichard, Cecily M. Quinn, Janice M. Walshe
Publikováno v:
Current Oncology, Vol 31, Iss 3, Pp 1302-1310 (2024)
Background: This study, using real-world data, assesses the impact of RS testing on treatment pathways and the associated economic consequences of such testing. This paper pertains to lobular breast cancer. Methods: A retrospective, observational stu
Externí odkaz:
https://doaj.org/article/c7e991104cdb4851bf2dfdfc09b20e5d
Autor:
Amanda J. Stock, Pierina Gonzalez Paredes, Luciana Previato de Almeida, Stanley D. Kosanke, Srinivaas Chetlur, Hannah Budde, Paul Wakenight, Theresa A. Zwingman, Aaron B.I. Rosen, Eric J. Allenspach, Kathleen J. Millen, Jane H. Buckner, David J. Rawlings, Jacquelyn A. Gorman
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Type 1 diabetes (T1D) is an autoimmune disease in which pancreatic islet β-cells are attacked by the immune system, resulting in insulin deficiency and hyperglycemia. One of the top non-synonymous single-nucleotide polymorphisms (SNP) associated wit
Externí odkaz:
https://doaj.org/article/348e199e09ab4f3484da495fb0461ba0
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Over the past decade, survival rates for extremely low gestational age neonates (ELGANs;
Externí odkaz:
https://doaj.org/article/05499f46b541495e9d7b2072d81ac7c9
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-20 (2020)
Abstract Chronic epilepsy has been associated with hippocampal abnormalities like neuronal loss, gliosis and granule cell dispersion. The granule cell layer of a normal human hippocampal dentate gyrus is traditionally regarded as a compact neuron-den
Externí odkaz:
https://doaj.org/article/59bf50a197f945b194e1c1f94f400a5a
Autor:
Daryl M. Okamura, Chris M. Brewer, Paul Wakenight, Nadia Bahrami, Kristina Bernardi, Amy Tran, Jill Olson, Xiaogang Shi, Szu-Ying Yeh, Adrian Piliponsky, Sarah J. Collins, Elizabeth D. Nguyen, Andrew E. Timms, James W. MacDonald, Theo K. Bammler, Branden R. Nelson, Kathleen J. Millen, David R. Beier, Mark W. Majesky
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103269- (2021)
Summary: Fibrosis-driven solid organ failure is an enormous burden on global health. Spiny mice (Acomys) are terrestrial mammals that can regenerate severe skin wounds without scars to avoid predation. Whether spiny mice also regenerate internal orga
Externí odkaz:
https://doaj.org/article/14339f301a224e7fbcad8ed0416f3953
Autor:
Achira Roy, Victor Z. Han, Angela M. Bard, Devin T. Wehle, Stephen E. P. Smith, Jan-Marino Ramirez, Franck Kalume, Kathleen J. Millen
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Patients harboring mutations in the PI3K-AKT-MTOR pathway-encoding genes often develop a spectrum of neurodevelopmental disorders including epilepsy. A significant proportion remains unresponsive to conventional anti-seizure medications. Understandin
Externí odkaz:
https://doaj.org/article/2d9e75212ff44739a7d5a2363a17616b
Autor:
Victor V. Chizhikov, Igor Y. Iskusnykh, Ekaterina Y. Steshina, Nikolai Fattakhov, Anne G. Lindgren, Ashwin S. Shetty, Achira Roy, Shubha Tole, Kathleen J. Millen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The contribution of long-range signaling to cortical gyrification remains poorly understood. In this study, authors demonstrate that the combined genetic loss of transcription factors Lmx1a and Lmx1b, expressed in the telencephalic dorsal midline neu
Externí odkaz:
https://doaj.org/article/5e9a3cae7cdf4bcbae7688176c6be113
Autor:
Scott L J Millen, Juhyeong Lee
Publikováno v:
Mechanical and Aerospace Engineering Faculty Publications
Millen, S L J & Lee, J 2023, ' Microscale modelling of lightning damage in fibre-reinforced composites ', Journal of Composite Materials, vol. 57, no. 10, pp. 1769-1789 . https://doi.org/10.1177/00219983231163271
Millen, S L J & Lee, J 2023, ' Microscale modelling of lightning damage in fibre-reinforced composites ', Journal of Composite Materials, vol. 57, no. 10, pp. 1769-1789 . https://doi.org/10.1177/00219983231163271
In this work, three-dimensional (3D) finite element simulations were undertaken to study the effects of lightning strikes on the microscale behaviour of continuous fibre-reinforced composite materials and to predict and understand complex lightning d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7523a548f640dc3d58084fda369b9173
https://doi.org/10.1177/00219983231163271
https://doi.org/10.1177/00219983231163271
Autor:
Branden R Nelson, Rebecca D Hodge, Ray AM Daza, Prem Prakash Tripathi, Sebastian J Arnold, Kathleen J Millen, Robert F Hevner
Publikováno v:
eLife, Vol 9 (2020)
The hippocampal dentate gyrus (DG) is a unique brain region maintaining neural stem cells (NCSs) and neurogenesis into adulthood. We used multiphoton imaging to visualize genetically defined progenitor subpopulations in live slices across key stages
Externí odkaz:
https://doaj.org/article/f6a9cc73f49c42e5945cb98f7ba78864
Autor:
Liam D. Hendrikse, Parthiv Haldipur, Olivier Saulnier, Jake Millman, Alexandria H. Sjoboen, Anders W. Erickson, Winnie Ong, Victor Gordon, Ludivine Coudière-Morrison, Audrey L. Mercier, Mohammad Shokouhian, Raúl A. Suárez, Michelle Ly, Stephanie Borlase, David S. Scott, Maria C. Vladoiu, Hamza Farooq, Olga Sirbu, Takuma Nakashima, Shohei Nambu, Yusuke Funakoshi, Alec Bahcheli, J. Javier Diaz-Mejia, Joseph Golser, Kathleen Bach, Tram Phuong-Bao, Patryk Skowron, Evan Y. Wang, Sachin A. Kumar, Polina Balin, Abhirami Visvanathan, John J. Y. Lee, Ramy Ayoub, Xin Chen, Xiaodi Chen, Karen L. Mungall, Betty Luu, Pierre Bérubé, Yu C. Wang, Stefan M. Pfister, Seung-Ki Kim, Olivier Delattre, Franck Bourdeaut, François Doz, Julien Masliah-Planchon, Wieslawa A. Grajkowska, James Loukides, Peter Dirks, Michelle Fèvre-Montange, Anne Jouvet, Pim J. French, Johan M. Kros, Karel Zitterbart, Swneke D. Bailey, Charles G. Eberhart, Amulya A. N. Rao, Caterina Giannini, James M. Olson, Miklós Garami, Peter Hauser, Joanna J. Phillips, Young S. Ra, Carmen de Torres, Jaume Mora, Kay K. W. Li, Ho-Keung Ng, Wai S. Poon, Ian F. Pollack, Enrique López-Aguilar, G. Yancey Gillespie, Timothy E. Van Meter, Tomoko Shofuda, Rajeev Vibhakar, Reid C. Thompson, Michael K. Cooper, Joshua B. Rubin, Toshihiro Kumabe, Shin Jung, Boleslaw Lach, Achille Iolascon, Veronica Ferrucci, Pasqualino de Antonellis, Massimo Zollo, Giuseppe Cinalli, Shenandoah Robinson, Duncan S. Stearns, Erwin G. Van Meir, Paola Porrati, Gaetano Finocchiaro, Maura Massimino, Carlos G. Carlotti, Claudia C. Faria, Martine F. Roussel, Frederick Boop, Jennifer A. Chan, Kimberly A. Aldinger, Ferechte Razavi, Evelina Silvestri, Roger E. McLendon, Eric M. Thompson, Marc Ansari, Maria L. Garre, Fernando Chico, Pilar Eguía, Mario Pérezpeña, A. Sorana Morrissy, Florence M. G. Cavalli, Xiaochong Wu, Craig Daniels, Jeremy N. Rich, Steven J. M. Jones, Richard A. Moore, Marco A. Marra, Xi Huang, Jüri Reimand, Poul H. Sorensen, Robert J. Wechsler-Reya, William A. Weiss, Trevor J. Pugh, Livia Garzia, Claudia L. Kleinman, Lincoln D. Stein, Nada Jabado, David Malkin, Olivier Ayrault, Jeffrey A. Golden, David W. Ellison, Brad Doble, Vijay Ramaswamy, Tamra E. Werbowetski-Ogilvie, Hiromichi Suzuki, Kathleen J. Millen, Michael D. Taylor
Publikováno v:
Nature, 609(7929), 1021-1028. Nature Publishing Group
Nature
Nature
Medulloblastoma (MB) comprises a group of heterogeneous paediatric embryonal neoplasms of the hindbrain with strong links to early development of the hindbrain 1–4. Mutations that activate Sonic hedgehog signalling lead to Sonic hedgehog MB in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ec0922f019d862bd9bb29cccaa1865
https://doi.org/10.1038/s41586-022-05215-w
https://doi.org/10.1038/s41586-022-05215-w