Zobrazeno 1 - 10
of 32
pro vyhledávání: '"J. Mielle"'
Autor:
C.I. Daïen, J. Tan, R. Audo, J. Mielle, L.E. Quek, J.R. Krycer, A. Angelatos, M. Duraes, G. Pinget, D. Ni, R. Robert, M.J. Alam, M.C.B. Amian, F. Sierro, A. Parmar, G. Perkins, S. Hoque, A.K. Gosby, S.J. Simpson, R.V. Ribeiro, C.R. Mackay, L. Macia
Publikováno v:
JCI Insight, Vol 6, Iss 7 (2021)
Autoimmune diseases are characterized by a breakdown of immune tolerance partly due to environmental factors. The short-chain fatty acid acetate, derived mostly from gut microbial fermentation of dietary fiber, promotes antiinflammatory Tregs and pro
Externí odkaz:
https://doaj.org/article/401b20ab9a7c4badb4eb837e24c5e0c1
Autor:
J. Mielle, Pierre Corbeau, Kristina Schreiber, R. Audo, Laurence Macia, Jacques Morel, Claire Daien, Bernard Combe, Claire Rempenault
Publikováno v:
Rheumatology
Rheumatology, 2021, 61 (5), pp.2185-2196. ⟨10.1093/rheumatology/keab639⟩
Rheumatology, Oxford University Press (OUP), 2021, ⟨10.1093/rheumatology/keab639⟩
Rheumatology, 2021, 61 (5), pp.2185-2196. ⟨10.1093/rheumatology/keab639⟩
Rheumatology, Oxford University Press (OUP), 2021, ⟨10.1093/rheumatology/keab639⟩
Objectives Chemokines (CKs) are key players of immune-cell homing and differentiation. CK receptors (CKRs) can be used to define T-cell functional subsets. We aimed to characterize the CKR profile of the regulatory B-cell subset B10+ cells and invest
Autor:
Jacques Morel, Philippe Guillpain, Claire Daien, A. Nutz, Bernard Combe, R. Audo, J. Mielle, Cécile Gaujoux-Viala
Publikováno v:
Immunologic Research. 69:107-113
Autor:
Duan Ni, Alexandra Sophie Angelatos, Charles R. Mackay, M.C.B. Amian, Claire Daien, Stephen J. Simpson, Remy Robert, M. Duraes, Jian Tan, S. Hoque, Alison K. Gosby, Rosilene V Ribeiro, Lake-Ee Quek, R. Audo, J. Mielle, Gabriela Pinget, A. Parmar, M.J. Alam, Laurence Macia, Frederic Sierro, James R. Krycer, G. Perkins
Publikováno v:
JCI Insight
JCI Insight, Vol 6, Iss 7 (2021)
JCI Insight, Vol 6, Iss 7 (2021)
Autoimmune diseases are characterized by a breakdown of immune tolerance partly due to environmental factors. The short-chain fatty acid acetate, derived mostly from gut microbial fermentation of dietary fiber, promotes antiinflammatory Tregs and pro
Autor:
B. Combe, J. Mielle, K. Scheider, Claire Daien, J. Morel, C. Rempenault, R. Audo, Pierre Corbeau
Publikováno v:
Revue du Rhumatisme. 87:A45-A46
Introduction Connus pour leur role pathogene dans la polyarthrite rhumatoide (PR), les lymphocytes B (LB) peuvent egalement y jouer un role anti-inflammatoire et protecteur, principalement grâce a la secretion d’interleukine-10 (IL-10). Cependant,
Autor:
Claire Daien, J. Morel, R. Audo, Laurence Macia, B. Combe, Cédric Lukas, J. Mielle, P. Sanchez, B. Riviere
Publikováno v:
Annals of the Rheumatic Diseases. 80:19.2-19
Background:Patients with rheumatoid arthritis (RA) have an altered gut microbiota (dysbiosis) (1-3). This microbiota interacts with intestinal epithelium which can lead to an increased intestinal permeability, responsible for the passage of antigens
Autor:
L. Manchon, K. Martin, C. Begon-Pescia, K. Chebli, Laure Lapasset, D. Scherrer, J. Mielle, C. Apolit, A. Garcel, A. Vautrin, J. Santo, J. Tazi, N. Campose, Claire Daien
Publikováno v:
Annals of the Rheumatic Diseases. 79:321-322
Background:ABX464 is a small oral molecule with a novel mode of action. It binds the Cap Binding Complex, involved in the biogenesis of RNAs and predominantly upregulates the expression of a microRNA miR-124 in PBMCs and T cells (1). miR-124 has been
Autor:
A. Nutz, J. Mielle, Cécile Gaujoux-Viala, R. Audo, Claire Daien, Jacques Morel, Philippe Guillpain, Bernard Combe
Publikováno v:
Immunologic Research. 69:114-114
Publikováno v:
Revue du Rhumatisme. 87:A26
Introduction On sait que les patients atteints de polyarthrite rhumatoide (PR) ont un microbiote intestinal different de celui des sujets sains. Ce microbiote peut influencer la barriere intestinale et entrainer une permeabilite intestinale accrue, r
Publikováno v:
Revue du Rhumatisme. 87:A44
Introduction Le tofacitinib (tofa) inhibe la signalisation des cytokines activees par JAK1 et JAK3. Cela conduit a une diminution des lymphocytes Th17 et une augmentation des lymphocytes T (LT) regulateurs. Les effets du tofa sur les lymphocytes B (L