Zobrazeno 1 - 10
of 75
pro vyhledávání: '"J. Middleditch"'
Autor:
Ghader Bashiri, Esther M. M. Bulloch, William R. Bramley, Madison Davidson, Stephanie M. Stuteley, Paul G. Young, Paul W. R. Harris, Muhammad S. H. Naqvi, Martin J. Middleditch, Michael Schmitz, Wei-Chen Chang, Edward N. Baker, Christopher J. Squire
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Poly-γ-glutamate tails are a distinctive feature of archaeal, bacterial, and eukaryotic cofactors, including the folates and F420. Despite decades of research, key mechanistic questions remain as to how enzymes successively add glutamates t
Externí odkaz:
https://doaj.org/article/4c044e76cc0a465894eb45f0998959cb
Autor:
Bin Lin, Benjamin J. Daniels, Martin J. Middleditch, Daniel P. Furkert, Margaret A. Brimble, Jessie Bong, Jonathan M. Stephens, Kerry M. Loomes
Publikováno v:
ACS Omega, Vol 5, Iss 15, Pp 8858-8866 (2020)
Externí odkaz:
https://doaj.org/article/79d3b7300beb4bb8aeaff4b699d92f01
Autor:
Reuben McGregor, Mei Lin Tay, Lauren H. Carlton, Paulina Hanson-Manful, Jeremy M. Raynes, Wasan O. Forsyth, Diane T. Brewster, Martin J. Middleditch, Julie Bennett, William John Martin, Nigel Wilson, Polly Atatoa Carr, Michael G. Baker, Nicole J. Moreland
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundAcute rheumatic fever (ARF) is a serious sequela of Group A Streptococcus (GAS) infection associated with significant global mortality. Pathogenesis remains poorly understood, with the current prevailing hypothesis based on molecular mimicr
Externí odkaz:
https://doaj.org/article/cec404aa12444ba6ba046c532886ac4a
Autor:
Lekha Jain, Mark H. Vickers, Bincy Jacob, Martin J. Middleditch, Daria A. Chudakova, Austen R. D. Ganley, Justin M. O’Sullivan, Jo K. Perry
Publikováno v:
Journal of Cell Communication and Signaling.
Abstract Growth hormone (GH) actions are mediated through binding to its cell-surface receptor, the GH receptor (GHR), with consequent activation of downstream signalling. However, nuclear GHR localisation has also been observed and is associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44c05b7ba9883f076b6742a7957cc2a2
https://doi.org/10.1007/s12079-023-00741-2
https://doi.org/10.1007/s12079-023-00741-2
Autor:
Xiaojing Lin, Yuliana Yosaatmadja, Maria Kalyukina, Martin J. Middleditch, Zhen Zhang, Xiaoyun Lu, Ke Ding, Adam V. Patterson, Jeff B. Smaill, Christopher J. Squire
Publikováno v:
ACS Med Chem Lett
[Image: see text] Aberration in FGFR4 signaling drives carcinogenesis and progression in a subset of hepatocellular carcinoma (HCC) patients, thereby making FGFR4 an attractive molecular target for this disease. Selective FGFR4 inhibition can be achi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200419c850590b39124ba936fda0d528
https://doi.org/10.1021/acsmedchemlett.9b00196
https://doi.org/10.1021/acsmedchemlett.9b00196
Autor:
Bin, Lin, Benjamin J, Daniels, Martin J, Middleditch, Daniel P, Furkert, Margaret A, Brimble, Jessie, Bong, Jonathan M, Stephens, Kerry M, Loomes
Publikováno v:
ACS Omega
Manuka honey is a premium food product with unique antimicrobial bioactivity. Concerns with mislabeled manuka honey require robust assays to determine authenticity. Lepteridine is a Leptospermum-specific fluorescent molecule with potential as an auth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee83550ee747fb19426b4abc3255dd79
https://pubmed.ncbi.nlm.nih.gov/32337448
https://pubmed.ncbi.nlm.nih.gov/32337448
Autor:
Helen C. Rees, Ben C. Maddison, Kevin C. Gough, David J. Middleditch, James R. M. Patmore, Keith Bishop
Publikováno v:
Ecology and Evolution
Current ecological surveys for great crested newts are time-consuming and expensive and can only be carried out within a short survey window. Additional survey methods which would facilitate the detection of rare or protected species such as the grea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71abf258761eee5319a20add7c47720d
https://doi.org/10.1002/ece3.1272
https://doi.org/10.1002/ece3.1272
Publikováno v:
Journal of Applied Ecology. 51:1450-1459
1. Knowledge of species distribution is critical to ecological management and conservation biology. Effective management requires the detection of populations, which can sometimes be at low densities and is usually based on visual detection and count
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29a749544ba73c3ed503e10952e118fb
https://doi.org/10.1111/1365-2664.12306
https://doi.org/10.1111/1365-2664.12306