Zobrazeno 1 - 10
of 296
pro vyhledávání: '"J. Middelberg"'
Publikováno v:
ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, Vol X-4-W4-2024, Pp 169-176 (2024)
Due to the necessary heat turnaround, buildings are increasingly seen as part of districts, e. g. Positive Energy Districts. Optimizing the energy efficiency of buildings is an essential part of implementing the heat turnaround. As a result, sensor/a
Externí odkaz:
https://doaj.org/article/700f7d20e2a64c2caf5801c4faa40be2
Autor:
David J. Pattinson, Simon H. Apte, Nani Wibowo, Tania Rivera-Hernandez, Penny L. Groves, Anton P. J. Middelberg, Denise L. Doolan
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Despite extensive research, the development of an effective malaria vaccine remains elusive. The induction of robust and sustained T cell and antibody response by vaccination is an urgent unmet need. Chimeric virus-like particles (VLPs) are a promisi
Externí odkaz:
https://doaj.org/article/0d170ccf359b4ae9a6c7c4cb5d45785b
Publikováno v:
AMB Express, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Antimicrobial peptides (AMPs) have significant potential as alternatives to classical antibiotics. However, AMPs are currently prepared using processes which are often laborious, expensive and of low-yield, thus hindering their research and
Externí odkaz:
https://doaj.org/article/697d9d3ba8ab4e719ca5ad6fc01b0a54
Publikováno v:
Biotechnology and Bioengineering. 119:2122-2133
In this study, we present the first integrated and continuous downstream process for the production of microbial virus-like particle vaccines. Modular murine polyomavirus major capsid VP1 with integrated J8 antigen was used as a model virus-like part
Autor:
David J. Pattinson, Simon H. Apte, Nani Wibowo, Yap P. Chuan, Tania Rivera-Hernandez, Penny L. Groves, Linda H. Lua, Anton P. J. Middelberg, Denise L. Doolan
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
An effective vaccine against the Plasmodium parasite is likely to require the induction of robust antibody and T cell responses. Chimeric virus-like particles are an effective vaccine platform for induction of antibody responses, but their capacity t
Externí odkaz:
https://doaj.org/article/2ab14d53e54c407b842d77fdd23cdede
Autor:
Jingxiu Bi, Yiran Qu, Anton P. J. Middelberg, Bingyang Zhang, Yan Sun, Yingli Wang, Shuang Yin
Publikováno v:
ACS Applied Bio Materials. 4:7147-7156
Human heavy-chain ferritin (HFn) and hepatitis B virus core (HBc) are both nanoparticle proteins presenting a well-oriented architecture with constant size and shape, which can be engineered to carry epitopes on the surface of the nanoparticle protei
Autor:
Shuang Yin, Jordan L. Pederick, Yan Sun, Yiran Qu, Yingli Wang, Bingyang Zhang, John B. Bruning, Jingxiu Bi, Anton P. J. Middelberg
Publikováno v:
Vaccine. 39:4830-4841
Human ferritin heavy chain, an example of a protein nanoparticle, has recently been used as a vaccine delivery platform. Human ferritin has advantages of uniform architecture, robust thermal and chemical stabilities, and good biocompatibility and bio
Publikováno v:
Biotechnology and Bioengineering. 119
Autor:
Anton P. J. Middelberg, Bingyang Zhang, Lijie Wang, Jingxiu Bi, Yiran Qu, Yan Jiao, Yan Sun, Shuang Yin
Publikováno v:
The Journal of Physical Chemistry B. 125:3830-3842
Human ferritin is regarded as an attractive and promising vaccine platform because of its uniform structure, good plasticity, and desirable thermal and chemical stabilities. Besides, it is biocompatible and presumed safe when used as a vaccine carrie
Autor:
Liang Zhao, Donna Mahony, Antonino S Cavallaro, Bing Zhang, Jun Zhang, James R Deringer, Chun-Xia Zhao, Wendy C Brown, Chengzhong Yu, Neena Mitter, Anton P J Middelberg
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0154295 (2016)
Anaplasma marginale is the most prevalent tick-borne livestock pathogen and poses a significant threat to cattle industry. In contrast to currently available live blood-derived vaccines against A. marginale, alternative safer and better-defined subun
Externí odkaz:
https://doaj.org/article/33d7682f13684316b7828b41c6fefe38