Zobrazeno 1 - 10 of 40 pro vyhledávání: '"J. Michalewsky"'
1
Combined solid-phase/solution synthesis of a 31-residue vasoactive intestinal peptide analog: general method for repetitive coupling of fragments without isolation and purification of intermediates
Autor: J. Michalewsky, Z. Zhao, Edgar P. Heimer, Mushtaq Ahmad, Wen Liu, Arthur Felix, A. Daniewski, Theodore Lambros
Publikováno v: The journal of peptide research : official journal of the American Peptide Society. 52(2)
A novel analog of vasoactive intestinal peptide (VIP) has been reported which exhibits high potency and enhanced duration of in vivo biological activity. This VIP analog, cyclo-(Lys21-Asp25)Ac[Glu8 Lys12 Nle17 Ala19, Asp25 Leu26,Lys27,28,Gly29,30,Thr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbec62c1affa75b37386d0fb038b8828
https://pubmed.ncbi.nlm.nih.gov/9727872
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2
Structure-activity studies on the vasoactive intestinal peptide pharmacophore. 1. Analogs of tyrosine
Autor: D R, Bolin, J, Cottrell, R, Garippa, J, Michalewsky, N, Rinaldi, B, Simko, M, O'Donnell
Publikováno v: International journal of peptide and protein research. 46(3-4)
From previous work, the primary functional groups, i.e. side chains, of the vasoactive intestinal peptide which are responsible for interaction with the VIP receptor have been identified. One of these sites, the side chain of tyrosine22 is essential
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::169f5d9993dea630bf893580d02f54e1
https://pubmed.ncbi.nlm.nih.gov/8537181
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7
Synthesis and biological activity of novel, potent and long-acting analogs of AC-CCK-7 with high affinity for peripheral (type A) receptors
Autor: W, Danho, R C, Makofske, J, Swistok, J, Michalewsky, T, Gabriel, N, Marks, M J, Berg, L, Baird, V, Geiler, G, Mackie
Publikováno v: Peptide research. 4(2)
Analogs of cholecystokinin (CCK-7) in which the N-terminal Tyr(SO3H) was acetylated, Asp6 replaced with Thr(SO3H) and Phe7 replaced with N-methyl-Phe were prepared by solid-phase peptide synthesis and evaluated for their receptor-binding activity and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7f4151144e3e883febe0bcc8a208d0de
https://pubmed.ncbi.nlm.nih.gov/1815779
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Plný text Recenzováno Digitální knihovna AV ČR
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