Zobrazeno 1 - 10
of 35
pro vyhledávání: '"J. Michael Thomson"'
Autor:
J. Michael Thomson, Wayne A. Parrott
Publikováno v:
BioTechniques, Vol 24, Iss 6, Pp 922-928 (1998)
Externí odkaz:
https://doaj.org/article/9a2eb3fb6ac84225bcf7757a21140788
Autor:
J. Michael Thomson, Mark M. Compton
Publikováno v:
BioTechniques, Vol 24, Iss 6, p 942 (1998)
Externí odkaz:
https://doaj.org/article/ea6f2b06d9314f3dbf534180694e9ef2
Autor:
Yangzom Doma Bhutia, Sau Wai Hung, Madeline Krentz, Dimal Patel, Dylan Lovin, Radhika Manoharan, J Michael Thomson, Rajgopal Govindarajan
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53436 (2013)
Overexpression of ribonucleotide reductase subunit M2 (RRM2), involved in deoxyribonucleotide synthesis, drives the chemoresistance of pancreatic cancer to nucleoside analogs (e.g., gemcitabine). While silencing RRM2 by synthetic means has shown prom
Externí odkaz:
https://doaj.org/article/87b32dde955443c8b2d59252ad02ceed
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8742 (2010)
The apicomplexan parasite Toxoplasma gondii can infect and replicate in virtually any nucleated cell in many species of warm-blooded animals; thus, it has evolved the ability to exploit well-conserved biological processes common to its diverse hosts.
Externí odkaz:
https://doaj.org/article/10ad6726743040ce91668a54b9dba71a
Autor:
Robert H. Whitehead, Carl R. Rankin, Bing Zhang, Robert J. Coffey, Jeffrey L. Franklin, Jay Snoddy, Shawn Levy, Mary Kay Washington, J. Michael Thomson
Publikováno v:
Biochemical and Biophysical Research Communications. 440:99-104
Recent progress has been made in the identification of protein-coding genes and miRNAs that are expressed in and alter the behavior of colonic epithelia. However, the role of long non-coding RNAs (lncRNAs) in colonic homeostasis is just beginning to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18205e0cfe7cf2f7bb625959a15afffd
https://doi.org/10.1016/j.bbrc.2013.09.040
https://doi.org/10.1016/j.bbrc.2013.09.040
Autor:
Karina L. Conkrite, Maggie Sundby, Scott Hammond, Shizuo Mukai, David Mu, David MacPherson, J. Michael Thomson
Publikováno v:
Genes & Development. 25:1734-1745
The miR-17∼92 cluster is a potent microRNA-encoding oncogene. Here, we show that miR-17∼92 synergizes with loss of Rb family members to promote retinoblastoma. We observed miR-17∼92 genomic amplifications in murine retinoblastoma and high expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9606189fa970b05eb27771934ccb990
https://doi.org/10.1101/gad.17027411
https://doi.org/10.1101/gad.17027411
Publikováno v:
RNA. 14:1539-1549
A hallmark of mammalian embryonic development is the widespread induction of microRNA (miRNA) expression. Surprisingly, the transcription of many of these small, noncoding RNAs is unchanged through development; rather, a post-transcriptional regulato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dba324456539d2d923a7aa0d38941f2
https://doi.org/10.1261/rna.1155108
https://doi.org/10.1261/rna.1155108
Publikováno v:
Journal of Biological Chemistry. 282:2130-2134
Micro-RNAs (miRNAs) are a class of non-coding RNAs that post-transcriptionally regulate gene expression via the RNA interference pathway. In addition to roles in normal development, miRNAs have recently been implicated in a range of human diseases, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbaf7f7d6805a5f2e1cef0e9d4227f78
https://doi.org/10.1074/jbc.c600252200
https://doi.org/10.1074/jbc.c600252200
Publikováno v:
Autophagy. 2:280-288
We have identified the Pichia pastoris Vac8 homolog, a 60-64 kDa armadillo repeat protein, and have examined the role of PpVac8 in the degradative pathways involving the yeast vacuole. We report here that PpVac8 is required for glucose-induced pexoph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ea49e4626aa713617b53c0fc2a997f6
https://doi.org/10.4161/auto.3164
https://doi.org/10.4161/auto.3164
Publikováno v:
Nature Methods. 1:47-53
MicroRNAs are short, noncoding RNA transcripts that post-transcriptionally regulate gene expression. Several hundred microRNA genes have been identified in Caenorhabditis elegans, Drosophila, plants and mammals. MicroRNAs have been linked to developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a151a685e5480f9f56b6b4b92971f4e3
https://doi.org/10.1038/nmeth704
https://doi.org/10.1038/nmeth704