Zobrazeno 1 - 10
of 20
pro vyhledávání: '"J. Michael Stolley"'
Autor:
Pamela C. Rosato, Sathi Wijeyesinghe, J. Michael Stolley, Christine E. Nelson, Rachel L. Davis, Luke S. Manlove, Christopher A. Pennell, Bruce R. Blazar, Clark C. Chen, Melissa A. Geller, Vaiva Vezys, David Masopust
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
The immunosuppressive tumor environment and the lack of functional anti-tumor immunity are major limiting factors in immunotherapy. Here the authors show that human and mouse tumors are infiltrated by virus-specific memory T cells, which can be harne
Externí odkaz:
https://doaj.org/article/5f068cea4ece4349a43cb5cd50da3600
Autor:
J. Michael Stolley, Milcah C. Scott, Vineet Joag, Alexander J. Dale, Timothy S. Johnston, Flavia Saavedra, Noah V. Gavil, Sahar Lotfi-Emran, Andrew G. Soerens, Eyob Weyu, Mark J. Pierson, Mark C. Herzberg, Nu Zhang, Vaiva Vezys, David Masopust
Publikováno v:
Journal of Experimental Medicine. 220
The oral mucosa is a frontline for microbial exposure and juxtaposes several unique tissues and mechanical structures. Based on parabiotic surgery of mice receiving systemic viral infections or co-housing with microbially diverse pet shop mice, we re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b54dcecb27e23324bd0a2811b199264f
https://doi.org/10.1084/jem.20221853
https://doi.org/10.1084/jem.20221853
Autor:
Vineet Joag, Stephen D O'Flanagan, Joshua M. Thiede, Clare F. Quarnstrom, Clayton K. Mickelson, Marc K. Jenkins, J. Michael Stolley, William E. Matchett, Tyler D. Bold, David Masopust, Michelle N Vu, Vaiva Vezys, Frances K. Shepherd, Vineet D. Menachery, Jennifer A Walter, Samuel Becker, Sathi Wijeyesinghe, Ryan A. Langlois, Eyob Weyu, Andrew G. Soerens
Publikováno v:
bioRxiv
J Immunol
J Immunol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the COVID-19 pandemic. Neutralizing Abs target the receptor binding domain of the spike (S) protein, a focus of successful vaccine efforts. Concerns have arisen that S-sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c205ab28b707a597b35f7b87b967bd
https://pubmed.ncbi.nlm.nih.gov/33948591
https://pubmed.ncbi.nlm.nih.gov/33948591
Autor:
J. Michael Stolley, Peter J. Southern, Siddheshvar Bhela, Thamotharampillai Dileepan, Maxim C.-J. Cheeran, Vineet Joag, Marc K. Jenkins, Sathi Wijeyesinghe, Joshua M. Thiede, Luca Schifanella, Jules A. Sangala, Clare F. Quarnstrom, Geoffrey T. Hart, Stephen D O'Flanagan, Sung-Wook Hong, Venkatramana D. Krishna, William E. Matchett, Noah V. Gavil, David Masopust, Sailaja Gangadhara, Tyler D. Bold, Eyob Weyu, Ryan A. Langlois, Vaiva Vezys, Rama Rao Amara, Andrew G. Soerens
Publikováno v:
J Immunol
The magnitude of SARS-CoV-2–specific T cell responses correlates inversely with human disease severity, suggesting T cell involvement in primary control. Whereas many COVID-19 vaccines focus on establishing humoral immunity to viral spike protein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dea03208cbb13c98035ec2035630766
https://pubmed.ncbi.nlm.nih.gov/33441437
https://pubmed.ncbi.nlm.nih.gov/33441437
Autor:
J. Michael Stolley, Elizabeth M. Steinert, Omar A. Adam, David Masopust, Lalit K. Beura, Sathi Wijeyesinghe, Mark Pierson, Roland Ruscher, Vaiva Vezys, Pamela C. Rosato
Publikováno v:
Nature
In metazoans, specific tasks are relegated to dedicated organs that are established early in development, occupy discrete locations and typically remain fixed in size. The adult immune system arises from a centralized haematopoietic niche that mainta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a971ad7aac31bb0a118d70aa439d8bbc
https://pubmed.ncbi.nlm.nih.gov/33731934
https://pubmed.ncbi.nlm.nih.gov/33731934
Publikováno v:
Curr Opin Immunol
Advances in the field of T cell memory, including the discovery of tissue residency, continue to add to the list of defined T cell subsets. Here, we briefly review the role of resident memory T cells (TRM) in protective immunity, and propose that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a106ba04650fdc7a5fc370d5454e401
https://europepmc.org/articles/PMC7198345/
https://europepmc.org/articles/PMC7198345/
Autor:
David K. Meyerholz, J. Michael Stolley, Hezkiel Nanda, Clayton K. Mickelson, Frances K. Shepherd, Sathi Wijeyesinghe, Vaiva Vezys, Sara E. Hamilton, Mark Pierson, Steven S. Shen, Ryan A. Langlois, Jessica K. Fiege, David Masopust, Katharine E. Block, William E. Matchett
Publikováno v:
Cell Reports Medicine
Summary In a recent issue of Cell Host and Microbe, Fiege and colleagues1 report that laboratory mice exposed to pathogens from pet-store mice exhibit impaired humoral immunity to influenza vaccination and display gene expression signatures that more
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff3263e40d2f8579a9d1842faa99fa3
https://doi.org/10.1016/j.chom.2021.10.001
https://doi.org/10.1016/j.chom.2021.10.001
Autor:
J. Michael Stolley, Jason S. Mitchell, Timothy Johnston, Kevin C. Osum, Sathi Wijeyesinghe, Ryan A. Langlois, Andrew G. Soerens, Pamela C. Rosato, David Masopust, Vineet Joag, Lalit K. Beura
Publikováno v:
The Journal of Experimental Medicine
Stolley et al. demonstrate that the decay of lung CD8+ T cell responses after primary influenza virus infection is contemporized by the egress of TRM-phenotype T cells from the lung to the draining mediastinal LN by retrograde migration, where they f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce8db75159dea3847addf39b55ab040c
https://pubmed.ncbi.nlm.nih.gov/32568362
https://pubmed.ncbi.nlm.nih.gov/32568362
Autor:
Luke S. Manlove, J. Michael Stolley, Christine E. Nelson, Vaiva Vezys, Pamela C. Rosato, Bruce R. Blazar, David Masopust, Christopher A. Pennell, Rachel L. Davis, Melissa A. Geller, Clark C. Chen, Sathi Wijeyesinghe
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Nature Communications
Nature Communications
The immunosuppressive tumor microenvironment limits the success of current immunotherapies. The host retains memory T cells specific for previous infections throughout the entire body that are capable of executing potent and immediate immunostimulato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cdc9cdb869d905e8ac8c978bb51055b
https://doi.org/10.1038/s41467-019-08534-1
https://doi.org/10.1038/s41467-019-08534-1
Autor:
Milcah C Scott, J. Michael Stolley, Mark J Pierson, Sathi Wijeyesinghe, Noah Veis Gavil, David Masopust
Publikováno v:
The Journal of Immunology. 206:103.28-103.28
Tissue resident memory T cells (TRM) represent the dominant antigen-experienced T cell subset that mediate local immunosurveillance in non-lymphoid tissues (NLT). Most accurately defined using migration assays, including parabiosis surgery and tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44cf0d4572982c80fbe8e42bf6176deb
https://doi.org/10.4049/jimmunol.206.supp.103.28
https://doi.org/10.4049/jimmunol.206.supp.103.28