Zobrazeno 1 - 10
of 129
pro vyhledávání: '"J. Michael Schurr"'
Autor:
J. Michael Schurr
Publikováno v:
The Journal of Physical Chemistry B. 123:7343-7353
Previous experimental studies of the effects of changes in sequence on the elastic constants and other properties of DNAs are analyzed using the recently parametrized two-state cooperative transition model. With appropriate assumptions regarding the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd21452bd3baa6f00acfa31792a8e099
https://doi.org/10.1021/acs.jpcb.9b05139
https://doi.org/10.1021/acs.jpcb.9b05139
Autor:
J. Michael Schurr
Publikováno v:
Quarterly reviews of biophysics. 54
Quantitative parameters for a two-state cooperative transition in duplex DNAs were finally obtained during the last 5 years. After a brief discussion of observations pertaining to the existence of the two-state equilibrium per se, the lengths, torsio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eeac33edb054768fcdec30fd3ea88e3
https://pubmed.ncbi.nlm.nih.gov/34003085
https://pubmed.ncbi.nlm.nih.gov/34003085
Autor:
J. Michael Schurr
Publikováno v:
The Journal of Physical Chemistry B. 121:5709-5717
Deforming an intrinsically straight elastic rod into a circle is shown to introduce an axial tension that acts to extend the rod, much like an externally applied force. The response of a circular DNA to such axial tension was reckoned using a previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b25173b2d06b283f69b05f2955b0b2f
https://doi.org/10.1021/acs.jpcb.7b01869
https://doi.org/10.1021/acs.jpcb.7b01869
Autor:
J. Michael Schurr
Publikováno v:
Biophysical Journal. 114:E1-E3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df520430b145bfd0b0a820dbc356899b
https://doi.org/10.1016/j.bpj.2018.04.033
https://doi.org/10.1016/j.bpj.2018.04.033
Autor:
J. Michael Schurr
Publikováno v:
Biophysical chemistry. 251
Review and analyses of the experimental data indicate that in nearly all cases bending elastic constants of the effective springs between bp of DNA actually undergo a net increase with increasing T from 278 to 315 K. The exceptions to this rule are b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64cb67daed6d003e081436492e6e503d
https://pubmed.ncbi.nlm.nih.gov/31158653
https://pubmed.ncbi.nlm.nih.gov/31158653
Autor:
J. Michael Schurr
Publikováno v:
The Journal of Physical Chemistry B. 119:6389-6400
The measured effective torsional rigidities of single twisted DNAs under various tensions conflict with theoretical predictions of Moroz and Nelson (MN) at low forces in the 0.25-2.0 pN range. However, MN theory was recently shown to agree well with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b81d9837665965fa4e85c326cded4cd
https://doi.org/10.1021/acs.jpcb.5b03174
https://doi.org/10.1021/acs.jpcb.5b03174
Autor:
J. Michael Schurr
Publikováno v:
The journal of physical chemistry. B. 121(44)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0708f7cc35ac43dcfd1cd78fcea57fe4
https://pubmed.ncbi.nlm.nih.gov/28463554
https://pubmed.ncbi.nlm.nih.gov/28463554
Publikováno v:
The Journal of Physical Chemistry B. 117:7626-7652
A macromolecule in a gradient of a cosolute that is preferentially (relative to the solvent) either attracted to or excluded from the domain of the macromolecule should experience a thermodynamic force and move, respectively, up or down the gradient.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::191e7729e342de4bf2814788acfecf36
https://doi.org/10.1021/jp302587d
https://doi.org/10.1021/jp302587d
Publikováno v:
The Journal of Physical Chemistry B. 112:13367-13380
The twist energy parameter ( E T) that governs the supercoiling free energy, and the linking difference (Delta l) are measured for p30delta DNA in solutions containing 0-40 w/v % ethylene glycol (EG). A plot of E T vs -ln a w, where a w is the water
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c6041402c139c8a2e853d4665bc3ed
https://doi.org/10.1021/jp802139a
https://doi.org/10.1021/jp802139a
Publikováno v:
The Journal of Physical Chemistry B. 112:13359-13366
Two different methods are proposed to estimate the persistence length ( P) of DNA from the measured torsion elastic constant (alpha) and the twist energy parameter ( E T ) that governs the supercoiling free energy. The first method involves Monte Car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e36e03d87b0387dbc869669f4ba82a6
https://doi.org/10.1021/jp801526w
https://doi.org/10.1021/jp801526w