Zobrazeno 1 - 10
of 24
pro vyhledávání: '"J. Michael Gee"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 8 (2015)
Microglia, the resident immune cells of the brain parenchyma, are highly responsive to tissue injury. Following cell damage, microglial processes redirect their motility from randomly scouting the extracellular space to specifically reaching toward t
Externí odkaz:
https://doaj.org/article/4200399b332d42138e2f7c4e782f2d47
Autor:
J. Michael Gee, Michael Karsy, Christian A. Bowers, Jonathan P Scoville, Mohammed A. Azab, Jian Guan, William T. Couldwell, Bornali Kundu
Publikováno v:
Neurosurgery. 84(5)
Background Pituitary adenomas are among the most common primary brain tumors. Recently, overlapping surgery has been curbed in many institutions because of the suggestion there might be more significant adverse events, despite several studies showing
Autor:
Angela Kalil, Pat Tanzi, Anna V. Savos, Kevin C. Cain, J. Michael Gee, Jessica Hadwin, Kelly T. Carter, Dean Shibata, Dannielle Zierath, Kyra J. Becker
Publikováno v:
Neurocritical Care. 14:244-252
Infection is common following stroke and is independently associated with worse outcome. Clinical studies suggest that infections occur more frequently in those individuals with stroke-induced immunologic dysfunction. This study sought to explore the
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 31:606-613
Alpha-melanocyte-stimulating hormone (MSH) is a neuropeptide with profound immunomodulatory properties; we evaluated the effects of α-MSH on stroke outcome and its ability to modulate the postischemic immune response. In Lewis rats subjected to 3 ho
Autor:
Jessica Hadwin, J. Michael Gee, Anna V. Savos, Matthew Thullbery, Dannielle Zierath, Angela Kalil, Kyra J. Becker
Publikováno v:
Neurocritical Care. 12:274-284
Animals subjected to an inflammatory insult with lipopolysaccharide (LPS) at the time of stroke are predisposed to develop a detrimental autoimmune response to myelin basic protein (MBP). In this study, we sought to determine whether other inflammato
Publikováno v:
Stroke. 39:1575-1582
Background and Purpose—Animals subjected to an inflammatory insult at the time of stroke are predisposed to the development of an inflammatory autoimmune response to brain. This response is associated with worse neurological outcome. Because induct
Publikováno v:
Stroke. 38:783-788
Antigen-nonspecific inflammation appears to contribute to postischemic brain injury. Because there is a breach in the integrity of the blood-brain barrier after stroke, the immune system encounters novel central nervous system (CNS) antigens that all
Autor:
J. Michael Gee
Publikováno v:
Journal of Natural History. 40:2611-2652
Three species of Parastenheliidae were found at a sampling site around low tide level on St Martin's Flat in the Isles of Scilly. The most abundant species in the community was identified as Parastenhelia ornatissima but detailed study, particularly
Autor:
J. Michael Gee
Publikováno v:
Journal of Natural History. 39:1961-1979
Bulbamphiascus incus sp. nov. is described from muddy sediments, high in organics, from below fish cages in salmon farms in two Scottish Lochs. It is characterized by the ornamentation of the urosome, the presence of an anvil‐shaped semi‐hyaline
Autor:
Nathan A. Smith, Markus Rothermel, Daniela Brunert, J. Michael Gee, Jennifer M. Ichida, Amy Talbot, Mario R. Capecchi, Sierra Palumbos, Peter J. West, Matt Wachowiak, Michael N. Economo, S. Craig Morris, John A. White, Petr Tvrdik, Fernando R. Fernandez, Jason D. Shepherd, Karen S. Wilcox
Publikováno v:
Neuron. 83(5)
SummaryNew strategies for introducing genetically encoded activity indicators into animal models facilitate the investigation of nervous system function. We have developed the PC::G5-tdT mouse line that expresses the GCaMP5G calcium indicator in a Cr