Zobrazeno 1 - 10
of 16
pro vyhledávání: '"J. Michael Charette"'
Autor:
Lauren A. Richardson, Benjamin J. Reed, J. Michael Charette, Emily F. Freed, Eric K. Fredrickson, Melissa N. Locke, Susan J. Baserga, Richard G. Gardner
Publikováno v:
Cell Reports, Vol 2, Iss 2, Pp 372-385 (2012)
Eukaryotic ribosome biogenesis requires hundreds of trans-acting factors and dozens of RNAs. Although most factors required for ribosome biogenesis have been identified, little is known about their regulation. Here, we reveal that the yeast deubiquit
Externí odkaz:
https://doaj.org/article/7b94dcba6e8b47738fa43b79c1687adb
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 323:R319-R330
The peroxisome proliferator-activated receptor γ coactivator 1 α (PGC-1α) is central to the regulation of cellular and mitochondrial energy homeostasis in mammals, but its role in other vertebrates remains unclear. Indeed, previous work suggests e
Autor:
Rafe, Helwer, J Michael, Charette
Publikováno v:
microPublication biology. 2022
RNA helicases are involved in nearly all aspects of RNA metabolism and factor prominently in ribosome assembly. The SSU processome includes 10 helicases and many helicase-cofactors. Together, they mediate the structural rearrangements that occur as p
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17701 (2011)
The small subunit (SSU) processome is a large ribonucleoprotein complex involved in small ribosomal subunit assembly. It consists of the U3 snoRNA and ∼72 proteins. While most of its components have been identified, the protein-protein interactions
Externí odkaz:
https://doaj.org/article/5cc95231188049c3a07177d3c7bd4e23
Publikováno v:
RNA. 24:77-89
Ribosome assembly is an evolutionarily conserved and energy intensive process required for cellular growth, proliferation, and maintenance. In yeast, assembly of the small ribosomal subunit (SSU) requires approximately 75 assembly factors that act in
Publikováno v:
Genes & Development. 29:862-875
Maturation of the large ribosomal subunit (LSU) in eukaryotes is a complex and highly coordinated process that requires the concerted action of a large, dynamic, ribonucleoprotein complex, the LSU processome. While we know that >80 ribosome biogenesi
Autor:
Eric K. Fredrickson, Emily F. Freed, J. Michael Charette, Melissa N. Locke, Richard G. Gardner, Benjamin J. Reed, Lauren A. Richardson, Susan J. Baserga
Publikováno v:
Cell Reports, Vol 2, Iss 2, Pp 372-385 (2012)
Summary Eukaryotic ribosome biogenesis requires hundreds of trans -acting factors and dozens of RNAs. Although most factors required for ribosome biogenesis have been identified, little is known about their regulation. Here, we reveal that the yeast
Publikováno v:
Wiley Interdisciplinary Reviews: RNA. 2:1-21
The small subunit (SSU) processome is a 2.2-MDa ribonucleoprotein complex involved in the processing, assembly, and maturation of the SSU of eukaryotic ribosomes. The identities of many of the factors involved in SSU biogenesis have been elucidated o
Publikováno v:
Nucleic Acids Research
Box C/D ribonucleoprotein (RNP) particles mediate O2′-methylation of rRNA and other cellular RNA species. In higher eukaryotic taxa, these RNPs are more complex than their archaeal counterparts, containing four core protein components (Snu13p, Nop5
Publikováno v:
The FASEB Journal. 28
Maturation of the 60S ribosomal subunit is a highly coordinated and dynamic process that begins in the nucleolus and ends in the cytoplasm. Over 80 different proteins, including several helicases, ...