Zobrazeno 1 - 10
of 159
pro vyhledávání: '"J. Mccarron"'
Publikováno v:
Cell Reports, Vol 39, Iss 5, Pp 110763- (2022)
Summary: T follicular helper (TFH) cells promote expansion of germinal center (GC) B cells and plasma cell differentiation. Whether cognate peptide-MHCII (pMHCII) density instructs selection and cell fate decisions in a quantitative manner remains un
Externí odkaz:
https://doaj.org/article/5dffdefe8835446eb1400765d2c303f5
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
. TGFβ is critical for limiting autoreactive responses of peripheral T cells. Here, the authors show that TGFβ signaling in thymocytes mediates elimination of self-reactive T cells and promotes the expression of self-antigens by medullary thymic ep
Externí odkaz:
https://doaj.org/article/87adb1264ac9462da662d251d3aa3047
Publikováno v:
Physical Review Research, Vol 3, Iss 4, p L042041 (2021)
We propose and demonstrate a technique that combines Raman scattering and optical cycling in molecules with diagonal Franck-Condon factors. This resonance Raman optical cycling manipulates molecules to behave like efficient fluorophores, with discret
Externí odkaz:
https://doaj.org/article/8ffde9a1c58f4b90abad42e214b0103c
Autor:
Siri Tahtinen, Ann-Jay Tong, Patricia Himmels, Jaehak Oh, Andres Paler-Martinez, Leesun Kim, Sara Wichner, Yoko Oei, Mark J. McCarron, Emily C. Freund, Zhainib Adel Amir, Cecile C. de la Cruz, Benjamin Haley, Craig Blanchette, Jill M. Schartner, Weilan Ye, Mahesh Yadav, Ugur Sahin, Lélia Delamarre, Ira Mellman
Publikováno v:
Nature Immunology. 23:532-542
The use of lipid-formulated RNA vaccines for cancer or COVID-19 is associated with dose-limiting systemic inflammatory responses in humans that were not predicted from preclinical studies. Here, we show that the 'interleukin 1 (IL-1)-interleukin 1 re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853754e3429271261548c4c29dc649ea
https://doi.org/10.1038/s41590-022-01160-y
https://doi.org/10.1038/s41590-022-01160-y
Autor:
Laura Broutier, Marion Creveaux, Jonathan Vial, Antonin Tortereau, Jean‐Guy Delcros, Guillaume Chazot, Mark J McCarron, Sophie Léon, Céline Pangault, Nicolas Gadot, Amélie Colombe, Marie‐Laure Boulland, Jonathan Blachier, Julien C Marie, Alexandra Traverse‐Glehen, Olivier Donzé, Catherine Chassagne‐Clément, Gilles Salles, Karin Tarte, Patrick Mehlen, Marie Castets
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 2, Pp 96-104 (2016)
Abstract DCC (Deleted in Colorectal Carcinoma) has been demonstrated to constrain tumor progression by inducing apoptosis unless engaged by its ligand netrin‐1. This has been shown in breast and colorectal cancers; however, this tumor suppressive f
Externí odkaz:
https://doaj.org/article/54487a895d0c470a8bb860763e426ec9
Autor:
Liam J. McCarron, Graeme Cooke, Michele Cariello, Emma H. Wilson, Serena A. Corr, Marco Amores, Claire Wilson, Beth I J Johnston, Manik Bhosale
Publikováno v:
ACS Applied Energy Materials
Organic-based electrodes for Li- and Na-ion batteries present attractive alternatives to commonly applied inorganic counterparts which can often carry with them supply-chain risks, safety concerns with thermal runaway, and adverse environmental impac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f40287beecb41f3e06d0c6d69ed53f
https://doi.org/10.1021/acsaem.0c00829
https://doi.org/10.1021/acsaem.0c00829
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications, 2019, 10, pp.5690. ⟨10.1038/s41467-019-13456-z⟩
Nature Communications, Nature Publishing Group, 2019, 10, ⟨10.1038/s41467-019-13456-z⟩
Nature Communications
Nature Communications, 2019, 10, pp.5690. ⟨10.1038/s41467-019-13456-z⟩
Nature Communications, Nature Publishing Group, 2019, 10, ⟨10.1038/s41467-019-13456-z⟩
In the thymus, the T lymphocyte repertoire is purged of a substantial portion of highly self-reactive cells. This negative selection process relies on the strength of TCR-signaling in response to self-peptide-MHC complexes, both in the cortex and med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6b2e3a18fb5b6b1d4d4021015c77ac
https://doaj.org/article/87adb1264ac9462da662d251d3aa3047
https://doaj.org/article/87adb1264ac9462da662d251d3aa3047
Autor:
Daniel J McCarron
Publikováno v:
New Journal of Physics, Vol 20, Iss 5, p 051001 (2018)
The Fast Track Communication by Petzold et al (2018 New J. Phys. 20 042001) demonstrates the first Zeeman slowing scheme for species with type-II optical cycling transitions. This new approach is directly applicable to those ^2 Σ molecules that have
Externí odkaz:
https://doaj.org/article/3c476c302d5444b79465e5ca50ffcade
Autor:
Samir Parekh, David R. Fooksman, Mark J. McCarron, Ilseyar Akhmetzyanova, Marta Chesi, P. Leif Bergsagel
Publikováno v:
Leukemia
The canonical plasma cell marker CD138 (syndecan-1) is highly expressed on the myeloma cell surface, but its functional role in vivo is unclear, as well as the ontogeny of CD138-high and CD138-negative (neg) myeloma cells. In this study we used an in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ec8ad7eedecc2074f7d9032b76cfde
https://doi.org/10.1038/s41375-019-0519-4
https://doi.org/10.1038/s41375-019-0519-4
Autor:
J. C. Shaw, D. J. McCarron
Publikováno v:
Physical Review A. 102
We demonstrate a cryogenic buffer gas-cooled molecular beam source capable of producing bright, continuous beams of cold and slow free radicals via laser ablation over durations of up to 60~seconds. The source design uses a closed liquid helium reser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed64a7754e7d14933e783a89d61c4f6d
https://doi.org/10.1103/physreva.102.041302
https://doi.org/10.1103/physreva.102.041302