Zobrazeno 1 - 10
of 14
pro vyhledávání: '"J. Matthew Meinig"'
Autor:
Christopher K. Cote, Kevin D. Mlynek, Christopher P. Klimko, Sergei S. Biryukov, Sherry Mou, Melissa Hunter, Nathaniel O. Rill, Jennifer L. Dankmeyer, Jeremey A. Miller, Yuli Talyansky, Michael L. Davies, J. Matthew Meinig, Stephanie A. Halasohoris, Anette M. Gray, Jade L. Spencer, Ashley L. Babyak, M. Kelly Hourihan, Bobby J. Curry, Ronald G. Toothman, Sara I. Ruiz, Xiankun Zeng, Keersten M. Ricks, Tamara L. Clements, Christina E. Douglas, Suma Ravulapalli, Christopher P. Stefan, Charles J. Shoemaker, Mindy G. Elrod, Jay E. Gee, Zachary P. Weiner, Ju Qiu, Joel A. Bozue, Nancy A. Twenhafel, David DeShazer
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 10, Pp 2056-2069 (2024)
In the United States in 2021, an outbreak of 4 cases of Burkholderia pseudomallei, the etiologic agent of melioidosis and a Tier One Select Agent (potential for deliberate misuse and subsequent harm), resulted in 2 deaths. The causative strain, B. ps
Externí odkaz:
https://doaj.org/article/8ea8582aa67e4680aa3494f13afc1315
Orally available nucleoside analog UMM-766 provides protection in a murine model of orthopox disease
Autor:
Rajini R. Mudhasani, Joseph W. Golden, Gregory C. Adam, Timothy J. Hartingh, Krishna P. Kota, David Ordonez, Corey R. Quackenbush, Julie P. Tran, Curtis Cline, Janice A. Williams, Xiankun Zeng, David B. Olsen, Linda A. Lieberman, Christopher Boyce, Anthony Ginnetti, J. Matthew Meinig, Rekha G. Panchal, Eric M. Mucker
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 4 (2024)
ABSTRACTAlthough smallpox has been eradicated, other orthopoxviruses continue to be a public health concern as exemplified by the ongoing Mpox (formerly monkeypox) global outbreak. While medical countermeasures (MCMs) previously approved by the Food
Externí odkaz:
https://doaj.org/article/53df8f67d29d4344baea9e9e6311d3a1
Autor:
Michelle Nelson, Kay B. Barnes, Carwyn H. Davies, Christopher K. Cote, J. Matthew Meinig, Sergei S. Biryukov, David N. Dyer, Ondraya Frick, Henry Heine, Denise A. Pfefferle, Amanda Horstman-Smith, Julie Barbaras, Sarah V. Harding
Publikováno v:
Antibiotics, Vol 12, Iss 3, p 506 (2023)
Burkholderia pseudomallei, the causative agent of the disease melioidosis, has been isolated from the environment in 45 countries. The treatment of melioidosis is complex, requiring lengthy antibiotic regimens, which can result in the relapse of the
Externí odkaz:
https://doaj.org/article/c25b9392bed3404bb724de9c85736d57
Autor:
Sandra McCurdy, Stephanie A Halasohoris, Ashley L Babyak, Sanae Lembirik, Randall Hoover, Mark Hickman, Jennifer Scarff, Christopher P Klimko, Christopher K Cote, J Matthew Meinig
Publikováno v:
Journal of Antimicrobial Chemotherapy. 78:810-816
ObjectivesTo evaluate the in vitro activity and in vivo efficacy of delafloxacin against Bacillus anthracis, the causative agent of anthrax.MethodsMICs were obtained according to CLSI guidelines for 30 virulent isolates and 14 attenuated antibiotic-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bce53b7d4342970801c2832ba50a95e
https://doi.org/10.1093/jac/dkad015
https://doi.org/10.1093/jac/dkad015
Autor:
Khushie Matharoo, Jennifer Chua, Junyoung R. Park, Susham Ingavale, Tanya M. Jelacic, Kayla M. Jurkouich, Jaimee R. Compton, J. Matthew Meinig, Donald Chabot, Arthur M. Friedlander, Patricia M. Legler
Publikováno v:
ACS infectious diseases. 8(10)
Polymers of d-glutamic acid (PDGA) form the capsule of the highly virulent Ames strain of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09322f319794bea1f8746256365b98cf
https://pubmed.ncbi.nlm.nih.gov/36102590
https://pubmed.ncbi.nlm.nih.gov/36102590
Autor:
Shannon Martin, Mariano Sanchez-Lockhart, Amy C. Shurtleff, Jeffrey R. Kugelman, Elizabeth E. Zumbrun, David L. Saunders, Travis K. Warren, Brett P. Eaton, Gustavo Palacios, Xiankun Zeng, Jens H. Kuhn, Allen J. Duplantier, Christopher L. Cooper, Farooq Nasar, Rajini Mudhasani, Rekha G. Panchal, Margaret L. Pitt, J Matthew Meinig, Ian Crozier, Chih-Yuan Chiang, Christopher D. Kane, Sandra L. Bixler, Sheli R. Radoshitzky, Karen A. Martins, Patrick L. Iversen, Melek M. E. Sunay
Publikováno v:
The Lancet. Infectious Diseases
Summary The PALM trial in the Democratic Republic of the Congo identified a statistically significant survival benefit for two monoclonal antibody-based therapeutics in the treatment of acute Ebola virus disease; however, substantial gaps remain in i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b72b43f9e4b77f081311c81aadaf6d7
https://doi.org/10.1016/s1473-3099(20)30282-6
https://doi.org/10.1016/s1473-3099(20)30282-6
Akademický článek
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Autor:
Tapasree Banerji, Skylar J. Ferrara, Hannah Sanford-Crane, Tania Banerji, Thomas S. Scanlan, J. Matthew Meinig, Dennis Bourdette
Publikováno v:
ACS Chemical Neuroscience. 8:2468-2476
The blood-brain barrier (BBB) can be a substantial impediment to achieving therapeutic levels of drugs in the CNS. Certain chemical functionality such as the carboxylic acid is a general liability for BBB permeability preventing significant CNS distr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d39b7aabe18e38093b801636ba00b4
https://doi.org/10.1021/acschemneuro.7b00239
https://doi.org/10.1021/acschemneuro.7b00239
Autor:
Priya Chaudhary, Lisa L. Kirkemo, Meredith D. Hartley, Edvinas Pocius, Dennis Bourdette, Mitra D. Shokat, Tapasree Banerji, Danielle Galipeau, Gail Marracci, Margaret J. DeBell, Ian J. Tagge, Thomas S. Scanlan, Evan Calkins, Shelby Van Leuven, J. Matthew Meinig, Skylar J. Ferrara, Tania Banerji, Hannah Miller, Ben Emery
Publikováno v:
JCI Insight. 4
Oligodendrocyte processes wrap axons to form neuroprotective myelin sheaths, and damage to myelin in disorders, such as multiple sclerosis (MS), leads to neurodegeneration and disability. There are currently no approved treatments for MS that stimula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e06eaa2b5e8989e0cb4bd909aa49795e
https://doi.org/10.1172/jci.insight.126329
https://doi.org/10.1172/jci.insight.126329
Autor:
Hannah Sanford-Crane, Thomas S. Scanlan, Tania Banerji, Tapasree Banerji, J. Matthew Meinig, Dennis Bourdette, Skylar J. Ferrara
Publikováno v:
ACS medicinal chemistry letters. 10(1)
[Image: see text] Thyroid hormone (TH) action is of clinical interest in treating demyelinating diseases of the central nervous system (CNS). Two amide prodrugs of sobetirome, a potent thyroid hormone agonist, were previously shown to significantly i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c2ab03d41a701923c6a03fda8418915
https://pubmed.ncbi.nlm.nih.gov/30655956
https://pubmed.ncbi.nlm.nih.gov/30655956