Zobrazeno 1 - 10
of 212
pro vyhledávání: '"J. Martin Bollinger"'
Autor:
Gang Liu, Debangsu Sil, Nunziata Maio, Wing-Hang Tong, J. Martin Bollinger, Carsten Krebs, Tracey Ann Rouault
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Heme biosynthesis depends on iron-sulfur (Fe-S) cluster biogenesis but the molecular connection between these pathways is not fully understood. Here, the authors show that the heme biosynthesis enzyme ALAD contains an Fe-S cluster, disruption of whic
Externí odkaz:
https://doaj.org/article/e72a170c1c0d4aa795c47a4475b86629
Autor:
Jeffrey W. Slater, Monica E. Neugebauer, Molly J. McBride, Debangsu Sil, Chi-Yun Lin, Bryce J. Katch, Amie K. Boal, Michelle C.Y. Chang, Alexey Silakov, Carsten Krebs, J. Martin Bollinger
Publikováno v:
bioRxiv
An aliphatic halogenase requires four substrates: 2-oxoglutarate (2OG), halide (Cl−or Br−), the halogenation target (“prime substrate”), and dioxygen. In well-studied cases, the three non-gaseous substrates must bind to activate the enzyme’
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b9fbd5470ea79412bbe4a20efb2a5d
https://doi.org/10.1101/2023.05.02.539147
https://doi.org/10.1101/2023.05.02.539147
Autor:
Chi-Yun Lin, Angel L. Muñoz Hernández, Tatiana N. Laremore, Alexey Silakov, Carsten Krebs, Amie K. Boal, J. Martin Bollinger
Publikováno v:
ACS Catalysis. 12:6968-6979
Autor:
Anastasia C. Manesis, Jeffrey W. Slater, Kenny Cantave, J. Martin Bollinger, Carsten Krebs, Amy C. Rosenzweig
Publikováno v:
Biochemistry
The diheme bacterial cytochrome c peroxidase (bCcP)/MauG superfamily is a diverse set of enzymes that remains largely uncharacterized. One recently discovered member, MbnH, converts a tryptophan residue in its substrate protein, MbnP, to kynurenine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6504117da0ffcc2c7714f596410e192d
https://europepmc.org/articles/PMC10083075/
https://europepmc.org/articles/PMC10083075/
Autor:
Molly J. McBride, Mrutyunjay A. Nair, Debangsu Sil, Jeffrey W. Slater, Monica E. Neugebauer, Michelle C. Y. Chang, Amie K. Boal, Carsten Krebs, J. Martin Bollinger
Publikováno v:
Biochemistry
The enzyme BesC from the β-ethynyl-L-serine biosynthetic pathway in Streptomyces cattleya fragments 4-chloro-L-lysine (produced from L-Lysine by BesD) to ammonia, formaldehyde, and 4-chloro-L-allylglycine and can analogously fragment L-Lys itself. B
Autor:
Molly J. McBride, Sarah R. Pope, Mrutyunjay A. Nair, Debangsu Sil, Xavier E. Salas-Solá, Carsten Krebs, J. Martin Bollinger, Amie K. Boal
Publikováno v:
Oxygen Sensing ISBN: 9781071630792
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a6f9821d5acfcd5d14a62f5bd5f2af3
https://doi.org/10.1007/978-1-0716-3080-8_9
https://doi.org/10.1007/978-1-0716-3080-8_9
Autor:
Theodore C. Pierson, Yan Li, Debangsu Sil, W. Marston Linehan, Bernard A. P. Lafont, Tracey A. Rouault, Carsten Krebs, J. Martin Bollinger, Nunziata Maio
Publikováno v:
Science
Mind your metals Iron–sulfur clusters are important cofactors for proteins involved in metabolism and electron transfer but are also sometimes found in enzymes involved in transcription and replication of DNA. In vitro expression of such enzymes ca
Autor:
Yun Ji Park, Richard J. Jodts, Jeffrey W. Slater, Reyvin M. Reyes, Valerie J. Winton, Rana A. Montaser, Paul M. Thomas, William B. Dowdle, Anahi Ruiz, Neil L. Kelleher, J. Martin Bollinger, Carsten Krebs, Brian M. Hoffman, Amy C. Rosenzweig
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(13)
Significance Methanobactins (Mbns), copper-binding peptidic compounds produced by some bacteria, are candidate therapeutics for human diseases of copper overload. The paired oxazolone-thioamide bidentate ligands of methanobactins are generated from c
Autor:
Chi-Yun Lin, Angel L. Muñoz, Tatiana N. Laremore, Alexey Silakov, Carsten Krebs, Amie K. Boal, J. Martin Bollinger, Jr.
Important bioactive natural products, including prostaglandin H2 and artemisinin, contain reactive endoperoxides. Known enzymatic pathways for endoperoxide installation require multiple hydrogen-atom transfers (HATs). For example, iron(II)- and 2-oxo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::217ab70cfa0b55bcedc0a28381465b8a
https://doi.org/10.26434/chemrxiv-2022-zvkk9
https://doi.org/10.26434/chemrxiv-2022-zvkk9
Autor:
Shyam R. Iyer, Shaun D. Wong, Edward I. Solomon, Martin Srnec, Makina Saito, Kyle D. Sutherlin, Kiyoung Park, Laura M. K. Dassama, Makoto Seto, J. Martin Bollinger, Yasuhiro Kobayashi, Yoshitaka Yoda, Carsten Krebs, Masayuki Kurokuzu
Publikováno v:
Journal of the American Chemical Society. 142:18886-18896
The α-ketoglutarate (αKG)-dependent oxygenases catalyze a diverse range of chemical reactions using a common high-spin FeIV═O intermediate that, in most reactions, abstract a hydrogen atom from the substrate. Previously, the FeIV═O intermediate