Early life adversity: Lasting consequences for emotional learning

Autor: Harm J. Krugers, J. Marit Arp, Hui Xiong, Sofia Kanatsou, Sylvie L. Lesuis, Aniko Korosi, Marian Joels, Paul J. Lucassen

Publikováno v: Neurobiology of Stress, Vol 6, Iss C, Pp 14-21 (2017)

The early postnatal period is a highly sensitive time period for the developing brain, both in humans and rodents. During this time window, exposure to adverse experiences can lastingly impact cognitive and emotional development. In this review, we b

Externí odkaz: https://doaj.org/article/27a91ddaecff4801874f401a8601886f

Blocking glucocorticoid receptors at adolescent age prevents enhanced freezing between repeated cue-exposures after conditioned fear in adult mice raised under chronic early life stress

Autor: J. Marit Arp, Melly S. Oitzl, Jan L. den Blaauwen, Guillén Fernández, Marian Joëls, Eline Bangert, Manila Loi, Judith P. ter Horst, Harm J. Krugers

Publikováno v: Neurobiology of Learning and Memory, 133, pp. 30-8
Neurobiology of Learning and Memory, 133, 30-38. Academic Press Inc.
Neurobiology of Learning and Memory, 133, 30. Academic Press Inc.
Neurobiology of Learning and Memory, 133, 30-8

Contains fulltext : 168332.pdf (Publisher’s version ) (Closed access) Early life adversity can have long-lasting impact on learning and memory processes and increase the risk to develop stress-related psychopathologies later in life. In this study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daec6fca24fcb09593fcc68664d96cc1
https://doi.org/10.1016/j.nlm.2016.05.009

Mineralocorticoid receptors guide spatial and stimulus-response learning in mice.

Autor: J Marit Arp, Judith P ter Horst, Sofia Kanatsou, Guillén Fernández, Marian Joëls, Harm J Krugers, Melly S Oitzl

Publikováno v: PLoS ONE, Vol 9, Iss 1, p e86236 (2014)

Adrenal corticosteroid hormones act via mineralocorticoid (MR) and glucocorticoid receptors (GR) in the brain, influencing learning and memory. MRs have been implicated in the initial behavioral response in novel situations, which includes behavioral

Externí odkaz: https://doaj.org/article/aba0df5d950a464a861a26a4a227b355