Zobrazeno 1 - 10
of 85
pro vyhledávání: '"J. Marden"'
Autor:
David B. Sauer, Jennifer J. Marden, Joseph C. Sudar, Jinmei Song, Christopher Mulligan, Da-Neng Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
DASS carboxylate transporters linked to metabolic diseases couple the Na+ gradient to nutrient uptake. Here, the authors unravel the structural basis by which Na+ binding coordinates substrate interactions, revealing a distinct coupling mechanism.
Externí odkaz:
https://doaj.org/article/91c93804bc594b8eab63527045308f23
Autor:
Abigail J. S. Armstrong, Kevin Quinn, Jennifer Fouquier, Sam X. Li, Jennifer M. Schneider, Nichole M. Nusbacher, Katrina A. Doenges, Suzanne Fiorillo, Tyson J. Marden, Janine Higgins, Nichole Reisdorph, Thomas B. Campbell, Brent E. Palmer, Catherine A. Lozupone
Publikováno v:
mSystems, Vol 6, Iss 3 (2021)
The gut microbiome in people living with HIV (PLWH) is of interest since chronic infection often results in long-term comorbidities. Metabolic disease is prevalent in PLWH even in well-controlled infection and has been linked with the gut microbiome
Externí odkaz:
https://doaj.org/article/baaac707c4d54cb8866daf593d6f1f25
Autor:
David B Sauer, Noah Trebesch, Jennifer J Marden, Nicolette Cocco, Jinmei Song, Akiko Koide, Shohei Koide, Emad Tajkhorshid, Da-Neng Wang
Publikováno v:
eLife, Vol 9 (2020)
Citrate, α-ketoglutarate and succinate are TCA cycle intermediates that also play essential roles in metabolic signaling and cellular regulation. These di- and tricarboxylates are imported into the cell by the divalent anion sodium symporter (DASS)
Externí odkaz:
https://doaj.org/article/539d34b7a7c747f68b846074d27714c4
Publikováno v:
Value in Health. 25:S369-S370
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cd6e97d329da9e706f3f786accf1a15
https://doi.org/10.1016/j.jval.2022.04.434
https://doi.org/10.1016/j.jval.2022.04.434
Autor:
C. McDonald, F. Muntoni, J. Marden, N. Goemans, A. Gomez-Lievano, A. Zhang, S. Ward, J. Signorovitch
Publikováno v:
Neuromuscular Disorders. 32:S69
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5cf6bc7e7401ef61963a6c9063c76f3
https://doi.org/10.1016/j.nmd.2022.07.115
https://doi.org/10.1016/j.nmd.2022.07.115
Autor:
Abigail J.S. Armstrong, Kevin Quinn, Jennifer Fouquier, Sam X. Li, Jennifer M. Schneider, Nichole M. Nusbacher, Katrina A. Doenges, Suzanne Fiorillo, Tyson J. Marden, Janine Higgins, Nichole Reisdorph, Thomas B. Campbell, Brent E. Palmer, Catherine A. Lozupone
Poor metabolic health, characterized by insulin resistance and dyslipidemia, is higher in people living with HIV (PLWH) and has been linked with inflammation, anti-retroviral therapy (ART) drugs, and ART-associated lipodystrophy (LD). Metabolic disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02c2ea0ff1a8436f009dcbe8d44f2e82
https://doi.org/10.1101/2021.03.12.435118
https://doi.org/10.1101/2021.03.12.435118
Autor:
David B Sauer, Noah Trebesch, Jennifer J Marden, Nicolette Cocco, Jinmei Song, Akiko Koide, Shohei Koide, Emad Tajkhorshid, Da-Neng Wang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcc06980b1d529eb54e7f0eccdb86dd7
https://doi.org/10.7554/elife.61350.sa2
https://doi.org/10.7554/elife.61350.sa2
Akademický článek
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Publikováno v:
Biochemical Journal. 411:531-541
c-Src has been shown to activate NF-kappaB (nuclear factor kappaB) following H/R (hypoxia/reoxygenation) by acting as a redox-dependent IkappaBalpha (inhibitory kappaB) tyrosine kinase. In the present study, we have investigated the redox-dependent m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9117bb217b37ad483f6eeb97bf3ce8ea
https://doi.org/10.1042/bj20071534
https://doi.org/10.1042/bj20071534
Autor:
Kathryn Nelson, Maged M. Harraz, Jennifer J. Marden, Henry L. Paulson, John F. Engelhardt, Meihui Luo, Aislinn J. Williams
Publikováno v:
Journal of Clinical Investigation. 117:2913-2919
Amyotrophic lateral sclerosis (ALS), one of the most common adult-onset neurodegenerative diseases, has no known cure. Enhanced redox stress and inflammation have been associated with the pathoprogression of ALS through a poorly defined mechanism. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a398ae028afe35dd6a5b7f5c68c1212
https://doi.org/10.1172/jci31265
https://doi.org/10.1172/jci31265