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Akademický článek

Kinetic characterization and allosteric inhibition of the Yersinia pestis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase).

Autor: Amanda Haymond, Chinchu Johny, Tyrone Dowdy, Brandon Schweibenz, Karen Villarroel, Richard Young, Clark J Mantooth, Trishal Patel, Jessica Bases, Geraldine San Jose, Emily R Jackson, Cynthia S Dowd, Robin D Couch

Publikováno v: PLoS ONE, Vol 9, Iss 8, p e106243 (2014)

The methylerythritol phosphate (MEP) pathway found in many bacteria governs the synthesis of isoprenoids, which are crucial lipid precursors for vital cell components such as ubiquinone. Because mammals synthesize isoprenoids via an alternate pathway

Externí odkaz: https://doaj.org/article/dd1996804d5d44a7a770cf35a3430aee

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Beyond ecosystem modeling: a roadmap to community cyberinfrastructure for ecological data‐model integration

Publikováno v: Fer, I, Gardella, A K, Shiklomanov, A N, Campbell, E E, Cowdery, E M, De Kauwe, M G, Desai, A, Duveneck, M J, Fisher, J B, Haynes, K D, Hoffman, F M, Johnston, M R, Kooper, R, LeBauer, D S, Mantooth, J, Parton, W J, Poulter, B, Quaife, T, Raiho, A, Schaefer, K, Serbin, S P, Simkins, J, Wilcox, K R, Viskari, T & Dietze, M C 2021, ' Beyond ecosystem modeling : A roadmap to community cyberinfrastructure for ecological data-model integration ', Global Change Biology, vol. 27, no. 1, pp. 13-26 . https://doi.org/10.1111/gcb.15409
Global Change Biology
Global change biology, vol 27, iss 1

In an era of rapid global change, our ability to understand and predict Earth's natural systems is lagging behind our ability to monitor and measure changes in the biosphere. Bottlenecks to informing models with observations have reduced our capacity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d68af97b38b2731cd7e43979eb5f216
https://centaur.reading.ac.uk/93658/8/gcb.15409.pdf

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Beyond Modeling: A Roadmap to Community Cyberinfrastructure for Ecological Data-Model Integration

In an era of rapid global change, our ability to understand and predict Earth's natural systems is lagging behind our ability to monitor and measure changes in the biosphere. Bottlenecks in our ability to process information have reduced our capacity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae7109cc55f01374406572a2594d934
https://doi.org/10.20944/preprints202001.0176.v1

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Ecology, distribution, and predictive occurrence modeling of Palmer’s chipmunk (Tamias palmeri): a high-elevation small mammal endemic to the Spring Mountains in southern Nevada, USA

Autor: Stacy J. Mantooth, Brett R. Riddle, Christopher Lowrey, Kathleen M. Longshore

Publikováno v: Journal of Mammalogy. 97:1033-1043

Although montane sky islands surrounded by desert scrub and shrub steppe comprise a large part of the biological diversity of the Basin and Range Province of southwestern North America, comprehensive ecological and population demographic studies for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a55458a2f27e15775133616afe298ea1
https://doi.org/10.1093/jmammal/gyw026

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A high-throughput screening campaign to identify inhibitors of DXP reductoisomerase (IspC) and MEP cytidylyltransferase (IspD)

Autor: Trishal Patel, Amanda Haymond, Karen Villarroel, Brandon Schweibenz, Clark J. Mantooth, Haley Ball, Richard Young, Allyson Dailey, Cynthia S. Dowd, Claire Johnson, Jessica Bases, Chinchu Johny, Robin D. Couch, Tyrone Dowdy

Publikováno v: Analytical biochemistry. 542

The rise of antibacterial resistance among human pathogens represents a problem that could change the landscape of healthcare unless new antibiotics are developed. The methyl erythritol phosphate (MEP) pathway represents an attractive series of targe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ea1c91da4fb3385b88e9ae1c904017
https://pubmed.ncbi.nlm.nih.gov/29180070

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Nonstructural Carbon in Woody Plants

Autor: J. Mantooth, Anna Sala, Rodrigo Vargas, Michael Dietze, Andrew D. Richardson, Mariah S. Carbone, Claudia I. Czimczik

Publikováno v: Annual review of plant biology, vol 65, iss 1
Dietze, MC; Sala, A; Carbone, MS; Czimczik, CI; Mantooth, JA; Richardson, AD; et al.(2014). Nonstructural Carbon in Woody Plants. Annual Review of Plant Biology, 65(1), 667-687. doi: 10.1146/annurev-arplant-050213-040054. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/67w7336q

Nonstructural carbon (NSC) provides the carbon and energy for plant growth and survival. In woody plants, fundamental questions about NSC remain unresolved: Is NSC storage an active or passive process? Do older NSC reserves remain accessible to the p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86bb5d244a5993ae253ac9e99218a0cb
https://doi.org/10.1146/annurev-arplant-050213-040054

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A quantitative assessment of a terrestrial biosphere model's data needs across North American biomes

Autor: Ryan Kelly, Dan Wang, Shawn P. Serbin, Carl C. Davidson, David LeBauer, Michael Dietze, Ankur R. Desai, Xiaohui Feng, Rob Kooper, Kenton McHenry, J. Mantooth

Publikováno v: Journal of Geophysical Research: Biogeosciences. 119:286-300

Terrestrial biosphere models are designed to synthesize our current understanding of how ecosystems function, test competing hypotheses of ecosystem function against observations, and predict responses to novel conditions such as those expected under

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::046b483debbe1e8d079fa37dafe9b653
https://doi.org/10.1002/2013jg002392

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Phylogeographic diversification of antelope squirrels (Ammospermophilus) across North American deserts

Autor: Robert W. Bryson, Brett R. Riddle, Stacy J. Mantooth, David J. Hafner

Publikováno v: Biological Journal of the Linnean Society. 109:949-967

We investigated the biogeographic history of antelope squirrels, genus Ammospermophilus, which are widely distributed across the deserts and other arid lands of western North America. We combined range-wide sampling of all currently recognized specie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d0040df3c241be357ef12ada704cc3e4
https://doi.org/10.1111/bij.12084

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Molecular Biogeography: The Intersection between Geographic and Molecular Variation

Autor: Brett R. Riddle, Stacy J. Mantooth

Publikováno v: Geography Compass. 5:1-20

The rapid growth of techniques employed in the generation and analysis of DNA variation has led to significant advances throughout the life sciences. Herein, we explore the impacts of this molecular revolution on the science of biogeography and how i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::34ea504674ac7fd3228e6b05b3b0beed
https://doi.org/10.1111/j.1749-8198.2009.00297.x

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