Zobrazeno 1 - 10
of 21
pro vyhledávání: '"J. MEULBROEK"'
Autor:
Leping Li, Paul A. Lartey, J. J. Plattner, Cynthia B. Curty, Clinton M. Yeung, Christina Louise Leone, Jeffrey Alder, Sheela A. Thomas, Hui-Ju Chen, Angela M. Nilius, Edwin O. Lundell, J. Meulbroek, David A. Degoey, Dariusz Wodka, Kenneth W. Funk, Vimal Kishore, David J. Grampovnik, Larry L. Klein
Publikováno v:
Bioorganic & Medicinal Chemistry. 8:1677-1696
The need for new therapies to treat systemic fungal infections continues to rise. Naturally occurring hexapeptide echinocandin B (1) has shown potent antifungal activity via its inhibition of the synthesis of beta-1,3 glucan, a key fungal cell wall c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc724ca9c006d1afbcf806937bd8078
https://doi.org/10.1016/s0968-0896(00)00097-3
https://doi.org/10.1016/s0968-0896(00)00097-3
Autor:
Nathan L. Shipkowitz, B Flamm, J. Meulbroek, M. Mitten, K. Jarvis, T Hutch, A. Oleksijew, L. Paige, Jacob J. Clement, Jeffrey Alder
Publikováno v:
Antimicrobial Agents and Chemotherapy. 39:971-975
The 2-pyridones are a new class of broad-spectrum orally bioavailable antibacterial agents. These compounds are potent bacterial DNA gyrase inhibitors which differ from fluoroquinolones by placement of the nitrogen atom in the ring juncture. ABT-719
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a72b0d91807d2fd9b3a8959d3643523
https://doi.org/10.1128/aac.39.4.971
https://doi.org/10.1128/aac.39.4.971
Autor:
M. Mitten, Ken Jarvis, Mary F. Henningfield, Jacob J. Clement, J. Meulbroek, Nate Shipkowitz, Tom Hutch, L. Paige, Jeffrey Alder
Publikováno v:
The Journal of Nutrition. 124:2156-2162
The effects of enteral formulations on the response of mice to infectious challenge with Listeria monocytogenes, influenza A or Candida albicans were studied to test the efficacy of specialized ingredients. CF-1 outbred female mice (12-15 g) were fed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b80a23a97c425a056d07947de472c4e
https://doi.org/10.1093/jn/124.11.2156
https://doi.org/10.1093/jn/124.11.2156
Autor:
Q. LI, D. T. W. CHU, A. CLAIBORNE, C. S. COOPER, C. M. LEE, K. RAYE, K. B. BERST, P. DONNER, W. WANG, L. HASVOLD, A. FUNG, Z. MA, M. TUFANO, R. FLAMM, L. L. SHEN, J. BARANOWSKI, A. NILIUS, J. ALDER, J. MEULBROEK, K. MARSH, D. CROWELL, Y. HUI, L. SEIF, L. M. MELCHER, R. HENRY, ET AL. ET AL.
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97887bbabaa0b2758b4d0db76f625af4
https://doi.org/10.1002/chin.199648159
https://doi.org/10.1002/chin.199648159
Autor:
Patty Ewing, Angela M. Nilius, Leping Li, Ping Zhong, Zhenkun Ma, Peter A. Nemoto, Richard F. Clark, Rupp Michael J, Zhensheng Cao, Daniel T. W. Chu, Michael J. Mitten, Jeff Alder, Robert K. Flamm, Ly Tam Phan, Hong Yong, George Griesgraber, Antony A Brazzale, Sanyi Wang, Jacob J. Plattner, Virginia D. Shortridge, Yat Sun Or, J. Meulbroek, Suoming Zhang, Xiaolin Zhang
Publikováno v:
Journal of medicinal chemistry. 44(24)
A novel series of erythromycin derivatives has been discovered with potent activity against key respiratory pathogens, including those resistant to erythromycin. These compounds are characterized by having an aryl group tethered to the C-6 position o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c93f42eb3edee1fedc89d387822195ed
https://pubmed.ncbi.nlm.nih.gov/11708916
https://pubmed.ncbi.nlm.nih.gov/11708916
Autor:
J. Meulbroek, K. Jarvis, A. Oleksijew, Patty Ewing, M. Mitten, K. Mollison, L. Hernandez, Yat Sun Or, A. Tovcimak, Zhenkun Ma, Angela M. Nilius, M. Nukkala, L. Paige, Jeffrey Alder, Robert K. Flamm
Publikováno v:
Antimicrobial agents and chemotherapy. 45(9)
ABT-773 is a novel ketolide effective against antibacterial-resistant respiratory tract pathogens. The pharmacokinetic profile of ABT-773 was studied in rats and consisted of a mean peak concentration in plasma of 1.07 μg/ml and an area under the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ab7014b850f502a7deae54a1a6ee59
https://pubmed.ncbi.nlm.nih.gov/11502533
https://pubmed.ncbi.nlm.nih.gov/11502533
In vivo efficacy of ABT-255 against drug-sensitive and -resistant Mycobacterium tuberculosis strains
Autor:
Ken Jarvis, L. Paige, Jeffrey Alder, Patty Ewing, Ann Tovcimak, M. Mitten, Mike Nukkula, J. Meulbroek, Andy Oleksijew, Daniel Chu
Publikováno v:
Antimicrobial agents and chemotherapy. 42(10)
Current therapy for pulmonary tuberculosis involves 6 months of treatment with isoniazid, pyrazinamide, rifampin, and ethambutol or streptomycin for reliable treatment efficacy. The long treatment period increases the probability of noncompliance, le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a1cb8df5ccf1ed759529768c5398fa
https://pubmed.ncbi.nlm.nih.gov/9756775
https://pubmed.ncbi.nlm.nih.gov/9756775
Autor:
H J, MEULBROEK
Publikováno v:
The Journal of the Kansas Medical Society. 65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::17faa1b9d91f77793483a5812a87df91
https://pubmed.ncbi.nlm.nih.gov/14216599
https://pubmed.ncbi.nlm.nih.gov/14216599
Autor:
H J, MEULBROEK
Publikováno v:
The Journal of the Kansas Medical Society. 66
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0494397826a2a99917ccbf6de7c5e02a
https://pubmed.ncbi.nlm.nih.gov/14270251
https://pubmed.ncbi.nlm.nih.gov/14270251
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.