Zobrazeno 1 - 10
of 32
pro vyhledávání: '"J. M. Wyss"'
Autor:
J M Wyss, Scott H. Carlson
Publikováno v:
Current Hypertension Reports. 1:246-253
Normally, the kidney plays the dominant role in setting long-term arterial pressure, and the nervous system acts primarily as a short-term regulator, adjusting arterial pressure to acute challenges (eg, standing, running, and stress). However, in sev
Publikováno v:
Journal of Clinical Investigation. 98:2060-2065
In spontaneously hypertensive rats (SHR), high NaCl diets increase arterial pressure and sympathetic nervous system activity by decreasing noradrenaline release in the anterior hypothalamic area (AHA), thereby reducing the activation of sympathoinhib
Autor:
Roujian Lu, L. E. Limbird, Qin Wang, Yunjia Chen, Kai Jiao, C. Cottingham, J. M. Wyss, N. Peng
Publikováno v:
Molecular pharmacology. 78(2)
We previously identified spinophilin as a regulator of alpha(2) adrenergic receptor (alpha(2)AR) trafficking and signaling in vitro and in vivo (Science 304:1940-1944, 2004). To assess the generalized role of spinophilin in regulating alpha(2)AR func
Publikováno v:
Maturitas. 66(2)
Plant derived products are consumed by a large percentage of the population to prevent, delay and ameliorate disease burden; however, relatively little is known about the efficacy, safety and underlying mechanisms of these traditional health products
Publikováno v:
Clinical and Experimental Hypertension. Part A: Theory and Practice. 13:1019-1031
The effects of lifetime captopril treatment on vasopressin (VP) were assessed in spontaneously hypertensive rats (SHR). Pregnant and nursing dams were treated with oral Captopril (100 mg/kg/day). After weaning, the pups were maintained on Captopril (
Publikováno v:
Planta Medica. 74
Publikováno v:
Journal of Clinical Investigation. 86:1985-1990
We have previously shown that the atrial natriuretic peptide (ANP) content of the anterior hypothalamic region of NaCl-sensitive spontaneously hypertensive rats (SHR-S) is higher than that of Wistar-Kyoto (WKY) rats. ANP has been shown to inhibit neu
Publikováno v:
Diabetes, obesitymetabolism. 5(6)
Restenosis after revascularization procedures is accelerated in persons with type 2 diabetes.The current study tested the hypothesis that the neointimal response to endovascular injury is enhanced in female obese Zucker (OZ) rats, a model of type 2 d
Autor:
J M Wyss, S H Carlson
Publikováno v:
The American journal of physiology. 277(1)
Peripheral osmoreceptors monitor dietary NaCl and modify central nervous system and renal sympathetic nervous system activity accordingly. Experimental evidence suggests that these responses are dependent on the hepatic nerves. Peripheral osmorecepto
Publikováno v:
Journal of hypertension. 12(11)
To compare muscle sympathetic nerve activity (MSNA) in age- and weight-matched African-Americans and American Caucasians with primary hypertension.Using microneurography, we compared MSNA at rest and in response to cold-pressor testing and handgrip e