Zobrazeno 1 - 10
of 356
pro vyhledávání: '"J. M. Weber"'
Autor:
Maria Barranco-Altirriba, Núria Alonso, Ralf J. M. Weber, Gavin R. Lloyd, Marta Hernandez, Oscar Yanes, Jordi Capellades, Andris Jankevics, Catherine Winder, Mireia Falguera, Josep Franch-Nadal, Warwick B Dunn, Alexandre Perera-Lluna, Esmeralda Castelblanco, Didac Mauricio
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Background In this study, we evaluated the lipidome alterations caused by type 1 diabetes (T1D) and type 2 diabetes (T2D), by determining lipids significantly associated with diabetes overall and in both sexes, and lipids associated with the
Externí odkaz:
https://doaj.org/article/883651a502c742d39e30e91a99f8b6e6
Autor:
Marina Idalia Rojo-López, Maria Barranco-Altirriba, Joana Rossell, Maria Antentas, Esmeralda Castelblanco, Oscar Yanes, Ralf J. M. Weber, Gavin R. Lloyd, Catherine Winder, Warwick B. Dunn, Josep Julve, Minerva Granado-Casas, Dídac Mauricio
Publikováno v:
Nutrients, Vol 16, Iss 12, p 1805 (2024)
Lipid functions can be influenced by genetics, age, disease states, and lifestyle factors, particularly dietary patterns, which are crucial in diabetes management. Lipidomics is an expanding field involving the comprehensive exploration of lipids fro
Externí odkaz:
https://doaj.org/article/55fd4c30732d4ce48cb9a83a4c2917d6
Autor:
Tara J. Bowen, Andrew D. Southam, Andrew R. Hall, Ralf J. M. Weber, Gavin R. Lloyd, Ruth Macdonald, Amanda Wilson, Amy Pointon, Mark R. Viant
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Untargeted metabolomics is an established approach in toxicology for characterising endogenous metabolic responses to xenobiotic exposure. Detecting the xenobiotic and its biotransformation products as part of the metabolomics analysis provi
Externí odkaz:
https://doaj.org/article/4910e9a54ea449d1b77c4b11d29fc8ec
Autor:
James B. Brown, Sasha A. Langley, Antoine M. Snijders, Kenneth H. Wan, Siti Nur Sarah Morris, Benjamin W. Booth, William W. Fisher, Ann S. Hammonds, Soo Park, Richard Weiszmann, Charles Yu, Jennifer A. Kirwan, Ralf J. M. Weber, Mark R. Viant, Jian-Hua Mao, Susan E. Celniker
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Brown et al. apply integrated omics and phenotypic screening to assess the role of the gut microbiome in modulating host resilience in Drosophila melanogaster. They find that Acetobacter tropicalis in gnotobiotic animals, is sufficient to rescue incr
Externí odkaz:
https://doaj.org/article/c3ab3d12ed36490693a2a628de744736
Autor:
David Allaway, Janet E. Alexander, Laura J. Carvell-Miller, Rhiannon M. Reynolds, Catherine L. Winder, Ralf J. M. Weber, Gavin R. Lloyd, Andrew D. Southam, Warwick B. Dunn
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Biomarker discovery using biobank samples collected from veterinary clinics would deliver insights into the diverse population of pets and accelerate diagnostic development. The acquisition, preparation, processing, and storage of biofluid samples in
Externí odkaz:
https://doaj.org/article/4e7cdc2ba08047af947f2a9c78d6b5a5
Autor:
Mark R. Viant, Timothy M. D. Ebbels, Richard D. Beger, Drew R. Ekman, David J. T. Epps, Hennicke Kamp, Pim E. G. Leonards, George D. Loizou, James I. MacRae, Bennard van Ravenzwaay, Philippe Rocca-Serra, Reza M. Salek, Tilmann Walk, Ralf J. M. Weber
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Lack of best practice guidelines currently limits the application of metabolomics in the regulatory sciences. Here, the MEtabolomics standaRds Initiative in Toxicology (MERIT) proposes methods and reporting standards for several important application
Externí odkaz:
https://doaj.org/article/4701db2695034f70a507e741b7841422
Autor:
Michael Sweet, Mark Bulling, Dorsa Varshavi, Gavin R. Lloyd, Andris Jankevics, Lukáš Najdekr, Ralf J. M. Weber, Mark R. Viant, Jamie Craggs
Publikováno v:
Frontiers in Marine Science, Vol 8 (2021)
Coral reefs are suffering unprecedented declines in health state on a global scale. Some have suggested that human assisted evolution or assisted gene flow may now be necessary to effectively restore reefs and pre-condition them for future climate ch
Externí odkaz:
https://doaj.org/article/cae140300cef498691cb7c5fef9f042c
Autor:
Dirk Jan Biemond, Menno Fitski, Gijs van der Ham, Maria Holtrop, Sander Karst, Suzanne van Leeuwen, Cristina Muru, Pieter Roelofs, Anna A. Ślączka, Giovanni Paolo di Stefano, Matthias Ubl, Gregor J. M. Weber
Publikováno v:
The Rijksmuseum Bulletin, Vol 68, Iss 1 (2020)
Externí odkaz:
https://doaj.org/article/d4191a6c30634f3ba2724d1578ebd36f
Publikováno v:
Metabolites, Vol 12, Iss 1, p 33 (2022)
Untargeted lipidomics has previously been applied to the study of daphnids and the discovery of biomarkers that are indicative of toxicity. Typically, liquid chromatography—mass spectrometry is used to measure the changes in lipid abundance in whol
Externí odkaz:
https://doaj.org/article/d4a3717de15a4d52b8c45cd469140806
Autor:
Julia M. Malinowska, Taina Palosaari, Jukka Sund, Donatella Carpi, Gavin R. Lloyd, Ralf J. M. Weber, Maurice Whelan, Mark R. Viant
Publikováno v:
Metabolites, Vol 12, Iss 1, p 52 (2022)
Regulatory bodies have started to recognise the value of in vitro screening and metabolomics as two types of new approach methodologies (NAMs) for chemical risk assessments, yet few high-throughput in vitro toxicometabolomics studies have been report
Externí odkaz:
https://doaj.org/article/94462e96c0024fd68ed3af5b611bcd89