Zobrazeno 1 - 10
of 14
pro vyhledávání: '"J. M. Trevillyan"'
Autor:
J. M. Trevillyan, E. E. Gardiner, R. K. Andrews, A. Maisa, A. C. Hearps, M. Al-Tamimi, S. M. Crowe, J. F. Hoy
Publikováno v:
Platelets, Vol 28, Iss 3, Pp 301-304 (2017)
HIV-positive patients are at increased risk for coronary artery disease (CAD); changes in platelet activation may play a role. This study was performed to determine if levels of soluble glycoprotein VI (sGPVI), a platelet-specific marker of activatio
Externí odkaz:
https://doaj.org/article/ebcf251aebf9481b9c1eaa56e97a4537
Publikováno v:
The Journal of Immunology. 145:3223-3230
Engagement of the TCR (CD3-Ti) by Ag/MHC, CD3 mAb, or lectin mitogen stimulates the very early tyrosine phosphorylation of several cellular substrates including TCR-zeta. The T cell specific protein-tyrosine kinase (PTK), p56lck, has been implicated
Autor:
K W, Mollison, T A, Fey, D M, Gauvin, R M, Kolano, M P, Sheets, M L, Smith, M, Pong, N M, Nikolaidis, B C, Lane, J M, Trevillyan, J, Cannon, K, Marsh, G W, Carter, Y S, Or, Y W, Chen, G C, Hsieh, J R, Luly
Publikováno v:
The Journal of investigative dermatology. 112(5)
T lymphocytes play a critical part in inflammatory skin diseases but are targeted by available therapies that have only partial efficacy, significant side-effects, or both. Because psoriasis, atopic dermatitis, and allergic contact hypersensitivity a
Autor:
K W, Mollison, T A, Fey, D M, Gauvin, M P, Sheets, M L, Smith, M, Pong, R, Krause, L, Miller, Y S, Or, M, Kawai, R, Wagner, P E, Wiedeman, R F, Clark, I W, Gunawardana, T A, Rhoades, C L, Henry, N P, Tu, N Y, BaMaung, H, Kopecka, L, Liu, Q, Xie, B C, Lane, J M, Trevillyan, K, Marsh, J R, Luly
Publikováno v:
Current pharmaceutical design. 4(5)
Drug therapy for the major inflammatory skin diseases, which include atopic dermatitis, psoriasis and allergic contact dermatitis, is often inadequate due to poor efficacy, toxicity, or both. Much research has focused on the macrolactam T cell inhibi
Autor:
Stevan W. Djuric, Q. M. Tang, Steve J. Ballaron, C. B. Putman, K. W. Mollison, Morey L. Smith, X. G. Chiou, P. Wiedeman, E. J. Gubbins, H. T. Smith, Noah Tu, Yuanwei Chen, C. R. Faltynek, David J. Madar, Usha Warrior, A. Buko, J. M. Trevillyan, M. P. Sheets
Publikováno v:
Archives of biochemistry and biophysics. 364(1)
Lck encodes a 56-kDa protein-tyrosine kinase, predominantly expressed in T lymphocytes, crucial for initiating T cell antigen receptor (TCR) signal transduction pathways, culminating in T cell cytokine gene expression and effector functions. As a con
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 149(1)
CD28 is a 44-kDa homodimeric receptor expressed on the majority of T cells. Engagement of the CD28 receptor by soluble anti-CD28 mAb in conjunction with PMA causes the induction of lymphokine/cytokine production and proliferation in resting T cells v
Publikováno v:
Journal of Biological Chemistry. 260:3041-3044
The relative abilities of insulin and the phorbol ester tumor promoter 12-O-tetradecanoyl phorbol 13-acetate (TPA) to lead to the phosphorylation of ribosomal protein S6 in vivo were compared in a Reuber H35 hepatoma cell line shown previously to be
Publikováno v:
Journal of Biological Chemistry. 259:897-902
The addition of the tumor promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA) to serum-starved quiescent Reuber H35 hepatoma cells results in a rapid 5- to 11-fold increase in the incorporation of 32Pi into a Mr = 32,000 ribosomal protein. The Mr =
Autor:
M L Pall, J M Trevillyan
Publikováno v:
Journal of Biological Chemistry. 257:3978-3986
A cyclic AMP-binding protein with a native molecular weight calculated to be 82,000 was purified 2,000-fold from Neurospora crassa. The apparent subunit molecular weight was 47,000 by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, suggest
Autor:
J M, Trevillyan, M L, Pall
Publikováno v:
The Journal of biological chemistry. 257(7)
A cyclic AMP-binding protein with a native molecular weight calculated to be 82,000 was purified 2,000-fold from Neurospora crassa. The apparent subunit molecular weight was 47,000 by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, suggest