Zobrazeno 1 - 10
of 73
pro vyhledávání: '"J. M. Simons"'
Autor:
Kelly Offermans, Nic G. Reitsam, Colinda C. J. M. Simons, Bianca Grosser, Jessica Zimmermann, Heike I. Grabsch, Bruno Märkl, Piet A. van den Brandt
Publikováno v:
Cancer & Metabolism, Vol 12, Iss 1, Pp 1-14 (2024)
Abstract Background Stroma AReactive Invasion Front Areas (SARIFA) is a recently identified haematoxylin & eosin (H&E)based histopathologic biomarker in gastrointestinal cancers, including colorectal cancer (CRC), defined as direct contact between tu
Externí odkaz:
https://doaj.org/article/ef24485a2135485c9e416501243ac481
Autor:
Florian Zeevat, Joost J. M. Simons, Tjalke A. Westra, Jan C. Wilschut, Nina M. van Sorge, Cornelis Boersma, Maarten J. Postma
Publikováno v:
Infectious Diseases and Therapy, Vol 13, Iss 3, Pp 481-499 (2024)
Abstract Introduction Invasive meningococcal disease (IMD) caused by Neisseria meningitidis is a rapidly progressing, rare disease that often presents as meningitis or sepsis. It mostly affects infants and adolescents, with high fatality rates or lon
Externí odkaz:
https://doaj.org/article/e533bfc6adb84078b0470a511629ab13
Autor:
Kelly Offermans, Josien C. A. Jenniskens, Colinda C. J. M. Simons, Iryna Samarska, Gregorio E. Fazzi, Jaleesa R. M. van derMeer, Kim M. Smits, Leo J. Schouten, Matty P. Weijenberg, Heike I. Grabsch, Piet A. van denBrandt
Publikováno v:
Cancer Medicine, Vol 12, Iss 2, Pp 1137-1156 (2023)
Abstract Background Previous research suggests that Warburg‐subtypes are related to potentially important survival differences in colorectal cancer (CRC) patients. In the present study, we investigated whether mutational subgroups based on somatic
Externí odkaz:
https://doaj.org/article/4f16f53a66a34d5caf70310b0fd58b56
Autor:
Josien C. A. Jenniskens, Kelly Offermans, Colinda C. J. M. Simons, Iryna Samarska, Gregorio E. Fazzi, Jaleesa R. M. van der Meer, Kim M. Smits, Leo J. Schouten, Matty P. Weijenberg, Heike I. Grabsch, Piet A. van den Brandt
Publikováno v:
Molecular Carcinogenesis, 61(12), 1099-1115. Wiley-Liss Inc.
KRAS mutations (KRASmut ), PIK3CAmut , BRAFmut , and deficient DNA mismatch repair (dMMR) have been associated with the Warburg effect. We previously reported differential associations between early-life energy balance-related factors (height, energy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001acf417ce52d82ca00cdbaa5ec86fd
https://doi.org/10.1002/mc.23459
https://doi.org/10.1002/mc.23459
Autor:
Josien C. A. Jenniskens, Kelly Offermans, Colinda C. J. M. Simons, Iryna Samarska, Gregorio E. Fazzi, Jaleesa R. M. van der Meer, Kim M. Smits, Leo J. Schouten, Matty P. Weijenberg, Heike I. Grabsch, Piet A. van den Brandt
Publikováno v:
Journal of Cancer Research and Clinical Oncology, 148(10), 2723-2742. Springer, Cham
Introduction KRAS mutations (KRASmut), PIK3CAmut, BRAFmut, and mismatch repair deficiency (dMMR) have been associated with the Warburg-effect. We previously observed differential associations between energy balance-related factors (BMI, clothing-size
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d9c0c94ce9b79f8068684ab5d7db02
https://doi.org/10.1007/s00432-022-04019-9
https://doi.org/10.1007/s00432-022-04019-9
Autor:
Josien C. A. Jenniskens, Kelly Offermans, Colinda C. J. M. Simons, Iryna Samarska, Gregorio E. Fazzi, Kim M. Smits, Leo J. Schouten, Matty P. Weijenberg, Heike I. Grabsch, Piet A. Brandt
Publikováno v:
International Journal of Cancer, 150(11), 1812-1824. Wiley
Early-life (childhood to adolescence) energy balance-related factors (height, energy restriction, BMI) have been associated with adult colorectal cancer (CRC) risk. Warburg-effect activation via PI3K/Akt-signaling might explain this link. We investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdc7e0c4136d624c421e891cc8a8136f
https://cris.maastrichtuniversity.nl/en/publications/0c2e21ad-9a7c-48ca-8df4-37120bcb24c6
https://cris.maastrichtuniversity.nl/en/publications/0c2e21ad-9a7c-48ca-8df4-37120bcb24c6
Autor:
Monika Stoll, Piet A. van den Brandt, Matty P. Weijenberg, Nadine S M Offermans, Colinda C. J. M. Simons
Publikováno v:
American Journal of Epidemiology, 191(3), 413-429. Oxford University Press
We empirically investigated genomic clusters associated with both height and postmenopausal breast cancer (BC) or colorectal cancer (CRC) (or both) in the Netherlands Cohort Study to unravel shared underlying mechanisms between height and these cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b23aca2b8d9a8f73af0a194f9efb747
https://doi.org/10.1093/aje/kwab259
https://doi.org/10.1093/aje/kwab259
Autor:
Kelly Offermans, Josien C. A. Jenniskens, Colinda C. J. M. Simons, Iryna Samarska, Gregorio E. Fazzi, Kim M. Smits, Leo J. Schouten, Matty P. Weijenberg, Heike I. Grabsch, Piet A. van den Brandt
Publikováno v:
Journal of Cancer Research and Clinical Oncology. Springer, Cham
Purpose Tumor location and tumor node metastasis (TNM) stage guide treatment decisions in colorectal cancer (CRC) patients. However, patients with the same disease stage do not benefit equally from adjuvant therapy. Hence, there remains an urgent cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45eceb139314169f8764df5b9044815
https://doi.org/10.1007/s00432-023-04581-w
https://doi.org/10.1007/s00432-023-04581-w
Autor:
Marc B. I. Lobbes, Maaike de Boer, Boen Lr Kam, Agnes Jager, Ernest J. T. Luiten, Thiemo J. A. van Nijnatten, Linetta B. Koppert, W. J. Vles, Marike Boskamp, Marian Be Menke, Wendy Kelder, Caroline Me Contant, David van Klaveren, Els R M van Haaren, Ingeborg Mares-Engelberts, Marjolein L. Smidt, Paul J. van Diest, Cees Verhoef, Harold J Heijmans, Paul Ra Sars, Leonie H. M. Smit, J. M. Simons, Carmen C. van der Pol
Publikováno v:
Cancer Research. 81:GS1-10
Rationale and research objective: As a result of neoadjuvant chemotherapy (NAC), approximately 1/3 of clinically node positive (cN+) breast cancer patients convert to a pathologic complete response (pCR) of the axilla. Targeted Axillary Dissection ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf20a233b5242a98c42110aca52a217d
https://doi.org/10.1158/1538-7445.sabcs20-gs1-10
https://doi.org/10.1158/1538-7445.sabcs20-gs1-10
Autor:
Kelly Offermans, Josien C. A. Jenniskens, Colinda C. J. M. Simons, Iryna Samarska, Gregorio E. Fazzi, Jaleesa R. M. van der Meer, Kim M. Smits, Leo J. Schouten, Matty P. Weijenberg, Heike I. Grabsch, Piet A. van den Brandt
Publikováno v:
Cancer Medicine, 12(2), 1137-1156. Wiley
BACKGROUND: Previous research suggests that Warburg-subtypes are related to potentially important survival differences in colorectal cancer (CRC) patients. In the present study, we investigated whether mutational subgroups based on somatic mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e6640084979c92e8d26baa94074368f
https://pubmed.ncbi.nlm.nih.gov/35785488
https://pubmed.ncbi.nlm.nih.gov/35785488