Zobrazeno 1 - 10
of 17
pro vyhledávání: '"J. M. Siehl"'
Publikováno v:
Oncology research and treatment. 40(3)
Lung cancer (LC) is one of the most common non-AIDS (acquired immune deficiency syndrome)-defining malignancies. It occurs more frequently in persons living with human immunodeficiency virus (PLWHIV) than in the HIV-negative population. Compared to t
Publikováno v:
Leukemia & Lymphoma. 48:1755-1763
This study was performed to investigate hematotoxicity and occurrence of PPE in patients with high-grade non-Hodgkins lymphoma treated with a modified CHOP regimen (CLAOP), where doxorubicin had been substituted by a noncardiotoxic pegliposomal doxor
Publikováno v:
Hematological Oncology. 25:132-139
The purpose of this study was to assess the efficacy and safety of pegylated liposomal doxorubicin in combination with cyclophosphamide and dexamethasone (CLAD). In this prospective open-label phase II study, 60 patients with advanced multiple myelom
Autor:
Nikolaos E. Bechrakis, Martin Schmidt-Hieber, Eckhard Thiel, R. Schuster, Alexander Schmittel, Michael H. Foerster, Ulrich Keilholz, J. M. Siehl, Peter Martus
Publikováno v:
Annals of Oncology. 17:1826-1829
Background: Several trials demonstrated efficacy of the gemcitabine/treosulfan (GeT) combination in metastatic uveal melamoma. This randomized phase II trial compared the GeT combination versus treosulfan alone (T) in this rare disease. Patients and
Autor:
Franz Mosthaf, Christoph Wyen, Markus Müller, J. M. Siehl, Marcus Hentrich, Manfred Hensel, Christian Hoffmann
Publikováno v:
Annals of hematology. 93(6)
AIDS-related aggressive B cell lymphoma (HIV-NHL) is the second most common HIV-associated malignancy. In contrast, Hodgkin-lymphoma (HL) is one of the most common non-AIDS-defining malignancies. Current evidence-based recommendations for the treatme
Autor:
C. Seidl, Wolf-Karsten Hofmann, J. M. Siehl, Erhard Seifried, Manfred Fischer, Carl M. Kirchmaier, Arnold Ganser, Dieter Hoelzer
Publikováno v:
Thrombosis Research. 100:27-34
Myelodysplastic syndromes (MDS) are characterized by a haematopoetic insufficiency that can lead to acute leukemia. A multistep pathogenesis caused by a clonal stem cell defect affecting several differentiation pathways has been proposed for MDS. Con
Autor:
Christoph Wyen, Markus M. Mueller, Timo Wolf, Mark Oette, J. M. Siehl, Albrecht Stoehr, Alexander Schultze, Marcus Hentrich, Jan-Christian Wasmuth, Ninon Taylor, Christian Hoffmann, Manfred Hensel, Gerd Fätkenheuer, Philipp Schommers, Daniel Gillor, Bjoern Jensen
Publikováno v:
Journal of Clinical Oncology. 34:7550-7550
7550Background: Since the introduction of combination antiretroviral therapy (ART) the outcome of HIV-associated lymphoma has significantly improved. However, aggressive lymphomas remain the most f...
Autor:
Antonia Busse, Ulrich Keilholz, Dieter Hoelzer, Stefan Schwartz, A. Rietz, Nicola Gökbuget, Eckhard Thiel, J. M. Siehl
Publikováno v:
Annals of hematology. 88(12)
Wilms’ tumor gene 1 (WT1) is gaining increasing attention as a therapeutic target molecule due to its common expression in acute leukemias and its involvement in cell proliferation. Here, we reported on WT1 messenger RNA expression levels at diagno
Autor:
Eckhard Thiel, J. M. Siehl
Publikováno v:
Targeted Therapies in Cancer ISBN: 9783540460909
A gain-of-function mutation of c-kit is the crucial step in tumorigenesis of gastrointestinal stromal tumors (GIST). Imatinib can block the activated receptor tyrosine kinase activity of c-kit. These findings made GIST an ideal candidate for evaluati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95a6a2a59e886d27a565ac3abdb15f11
https://doi.org/10.1007/978-3-540-46091-6_12
https://doi.org/10.1007/978-3-540-46091-6_12
Publikováno v:
Annals of hematology. 83(12)
WT1 is a transcription factor involved in differentiation and proliferation of acute myeloid leukemia (AML) blasts and is expressed in 90% of cases, as determined by nested reverse transcription polymerase chain reaction (RT-PCR). It is proposed to b