Zobrazeno 1 - 10
of 15
pro vyhledávání: '"J. M. Rodríguez-Sasiaín"'
Autor:
C. Aguirre, I. Ayani, G. Gutiérrez, J. M. Rodríguez-Sasiaín, A. Madariaga, M. J. Martínez-Bengoechea
Publikováno v:
Pharmacoepidemiology and Drug Safety. 8:529-534
The main objective of this study was to analyse the minimum direct cost to the Public Health System (PHS) of diagnosing and treating those patients attended to in the emergency ward (EW) for suspected adverse drug reaction (ADR). The cases were colle
Autor:
Aguirre C, Rosario Calvo, J. De Castro, Mauricio Garrido, Enrique J. Gómez, J. M. Rodríguez-Sasiaín
Publikováno v:
Biopharmaceutics & Drug Disposition. 17:551-563
The effect of omeprazole (2 mg kg-1 i.v.) on respiratory depression induced in rats by acute oral methadone administration (5 mg kg-1) was examined and compared with control animals that only received methadone. Quantitative assessments of arterial P
Autor:
I, Ayani, C, Aguirre, G, Gutiérrez, A, Madariaga, J M, Rodríguez-Sasiaín, M J, Martínez-Bengoechea
Publikováno v:
Pharmacoepidemiology and drug safety. 8(7)
The main objective of this study was to analyse the minimum direct cost to the Public Health System (PHS) of diagnosing and treating those patients attended to in the emergency ward (EW) for suspected adverse drug reaction (ADR). The cases were colle
Publikováno v:
Journal of Pharmacy and Pharmacology. 42:164-166
Penbutolol is a β-adrenoceptor antagonist that is extensively bound to α1-acid glycoprotein (α1-AGP), a protein that increases in inflammatory diseases thereby binding more drug in such conditions. Changes in serum binding can lead to modification
Publikováno v:
Biopharmaceuticsdrug disposition. 17(7)
The effect of omeprazole (2 mg kg-1 i.v.) on respiratory depression induced in rats by acute oral methadone administration (5 mg kg-1) was examined and compared with control animals that only received methadone. Quantitative assessments of arterial P
Autor:
C, Aguirre, I F, Trocóniz, A, Valdivieso, R M, Jiménez, J P, González, R, Calvo, J M, Rodríguez-Sasiaín
Publikováno v:
Research communications in molecular pathology and pharmacology. 92(1)
The pharmacokinetic and pharmacodynamic profiles of penbutolol were examined in healthy volunteers and in cancer patients using a pharmacokinetic/pharmacodynamic (pk/pd) model. After receiving a 40 mg single oral dose of penbutolol, the absorption ra
Publikováno v:
Research communications in molecular pathology and pharmacology. 89(3)
In a group of mice bearing experimentally induced tumors, the protein binding of mianserin in vitro was measured and compared with a control group. The analgesic effect and the brain uptake of drug was also compared with a control group after an intr
Autor:
J. P. Gonzalez, J M Rodríguez-Sasiaín, Carmelo Aguirre, Andrés Valdivieso, P. du Souich, R M Jiménez, Rosario Calvo
Publikováno v:
European journal of clinical pharmacology. 48(3-4)
The effect of ascorbic acid on the availability of propranolol has been examined. After oral administration of propranolol 80 mg with or without ascorbic acid pretreatment (2 g), the plasma concentrations and urinary excretion of propranolol and its
Publikováno v:
Revista espanola de anestesiologia y reanimacion. 41(6)
a) To study the binding of propofol to proteins in plasma samples from healthy volunteers and in solutions of albumin and alpha 1-acid glycoprotein (AGA); b) to describe the nature of the bond and possible interactions with other substances that are
Publikováno v:
Methods and findings in experimental and clinical pharmacology. 13(10)
The in vitro effect of the halothane metabolite, trifluoroacetic acid, on the protein binding of three different benzodiazepines (diazepam, lorazepam and midazolam) has been investigated. Furthermore, protein binding of these drugs was studied in ser