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STUDIES ON OXIDATION AND REDUCTION BY PNEUMOCOCCUS : VIII. NATURE OF THE OXIDATION-REDUCTION SYSTEMS IN STERILE PNEUMOCOCCUS EXTRACTS

Autor: J M, Neill, O T, Avery

Publikováno v: The Journal of Experimental Medicine

1. The systems responsible for oxidation and reduction in the pneumococcus cell have been shown to consist of two components, the nature of which has been discussed. 2. The oxidizing and reducing power of active extracts of pneumococci is inactivated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9641fe7e8b7b775ba1008e2171830f3a
https://pubmed.ncbi.nlm.nih.gov/19868988

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STUDIES ON OXIDATION AND REDUCTION BY PNEUMOCOCCUS : VI. THE OXIDATION OF ENZYMES IN STERILE EXTRACTS OF PNEUMOCOCCUS

Autor: J M, Neill, O T, Avery

Publikováno v: The Journal of Experimental Medicine

1. Certain enzymes of Pneumococcus are destroyed by oxidizing agents formed when sterile extracts of the cellular substances are exposed to air. The carbohydrate-hydrolyzing enzymes (sucrase, raffinase, inulase, and amylase) are the most easily inact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d2dc6ce58507eb6932f658142275e09f
https://pubmed.ncbi.nlm.nih.gov/19868928

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STUDIES ON IMMUNOLOGICAL RELATIONSHIPS AMONG THE PNEUMOCOCCI : II. A COMPARISON OF THE ANTIBODY RESPONSES OF MICE AND OF RABBITS TO IMMUNIZATION WITH TYPICAL TYPE III PNEUMOCOCCI AND TO IMMUNIZATION WITH A RELATED STRAIN

Autor: A L, Harris, J Y, Sugg, J M, Neill

Publikováno v: The Journal of Experimental Medicine

The paper reports an experimental comparison of the antibody responses of mice and of rabbits to immunization with typical Type III pneumococci and a strain related to Type III. The results as a whole show that the relative antigenic effectiveness of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d979dcbfe7afac20ab8d85a9332612bd
https://pubmed.ncbi.nlm.nih.gov/19869455

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STUDIES ON THE OXIDATION AND REDUCTION OF IMMUNOLOGICAL SUBSTANCES : II. THE HEMOTOXIN OF THE WELCH BACILLUS

Autor: J M, Neill

Publikováno v: The Journal of Experimental Medicine

A study has been made of the oxidation and reduction of the hemotoxin of the Welch bacillus. The oxidation of the lysin results in the loss of its hemolytic activity. The "inactive" oxidation product of the Welch lysin may be reversed to the "active"

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0b8ad64a6cdec88dfa656552a0f0a83e
https://pubmed.ncbi.nlm.nih.gov/19869181

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STUDIES ON OXIDATION AND REDUCTION BY PNEUMOCOCCUS : V. THE DESTRUCTION OF OXYHEMOGLOBIN BY STERILE EXTRACTS OF PNEUMOCOCCUS

Autor: J M, Neill, O T, Avery

Publikováno v: The Journal of Experimental Medicine

1. Sterile broth extracts of unwashed pneumococci actively destroy hemoglobin to methemoglobin and lower degradation products. 2. Sterile saline extracts of washed pneumococci do not by themselves form methemoglobin; extracts of this type may be comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::43d0f3f7d50200884d35903fd9231d3f
https://pubmed.ncbi.nlm.nih.gov/19868882

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STUDIES ON BACTERIAL ENZYMES : VII. LACTASE AND LIPASE OF THE COLON BACILLUS

Autor: L, Lowenstein, W L, Fleming, J M, Neill

Publikováno v: The Journal of Experimental Medicine

Colon bacilli possess endocellular heat-labile lactase and lipase enzymes which remain operative in sterile filtered solutions of the intracellular substances obtained through physical disintegration the bacillary bodies. The demonstration of the lac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::354b8ac2ab41ed3077c45f22b8c2859d
https://pubmed.ncbi.nlm.nih.gov/19869557

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STUDIES ON THE OXIDATION AND REDUCTION OF IMMUNOLOGICAL SUBSTANCES : III. TETANOLYSIN

Autor: J M, Neill

Publikováno v: The Journal of Experimental Medicine

A preliminary study was made of the rate of formation of tetanolysis and of the effect of glucose upon the lysin production. The heat lability of tetanolysin was next compared with that of the lysins of other bacteria. Finally the methods used to est

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f4f8badab344c2bb2e0854baebce898d
https://pubmed.ncbi.nlm.nih.gov/19869182

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STUDIES ON BACTERIAL ENZYMES : I. MENINGOCOCCUS MALTASE

Autor: J M, Neill, E L, Gaspari

Publikováno v: The Journal of Experimental Medicine

Meningococci possess an endocellular maltase enzyme. The splitting of maltose by this enzyme has been demonstrated by a biological method based upon the acid fermentation of glucose by bacteria which have little or no action upon maltose.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::50567f317cd5985ff0f4079d275cebfe
https://pubmed.ncbi.nlm.nih.gov/19869235

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STUDIES ON OXIDATION AND REDUCTION BY PNEUMOCOCCUS : III. REDUCTION OF METHYLENE BLUE BY STERILE EXTRACTS OF PNEUMOCOCCUS

Autor: O T, Avery, J M, Neill

Publikováno v: The Journal of Experimental Medicine

1. Sterile broth extracts of unwashed pneumococci, entirely free from living or intact cells, actively reduce methylene blue. 2. Sterile extracts prepared by extracting washed pneumococci in phosphate solution are unable by themselves to reduce methy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bdec969b8862a60235690ca4aab394f5
https://pubmed.ncbi.nlm.nih.gov/19868864

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