Zobrazeno 1 - 10
of 49
pro vyhledávání: '"J. M. Lefauconnier"'
Publikováno v:
Neuroscience Research. 43:335-342
Transport of a polyamine (PA), spermidine (SPMD) into rat brain at various early postischemic periods was studied. Rats underwent 20 min of four-vessel occlusion (4VO) followed by 5, 10, 30 and 60 min of recirculation (RC) periods with natural brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f71d39331f9ce362d53013b8c0f8a7b
https://doi.org/10.1016/s0168-0102(02)00059-7
https://doi.org/10.1016/s0168-0102(02)00059-7
Autor:
C, Rousselle, M, Smirnova, P, Clair, J M, Lefauconnier, A, Chavanieu, B, Calas, J M, Scherrmann, J, Temsamani
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 296(1)
Doxorubicin delivery to the brain is often restricted because of the poor transport of this therapeutic molecule through the blood-brain barrier (BBB). To overcome this problem, we have recently developed a technology, Pep:trans, based on short natur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f3ef5df6a06b98ba076c008b303a5c1f
https://pubmed.ncbi.nlm.nih.gov/11123372
https://pubmed.ncbi.nlm.nih.gov/11123372
Autor:
J. M. Lefauconnier, H. Benrabh
Publikováno v:
Neurochemical research. 21(10)
We report the application of multiple time regression analysis with the in situ brain perfusion technique to measure the rates of passage between blood and brain for [14C] L-proline, [14C] L-alanine, and [14C] alpha-aminoisobutyric acid (AIB) and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81677e550173a3d38fda047c613028fd
https://pubmed.ncbi.nlm.nih.gov/8923485
https://pubmed.ncbi.nlm.nih.gov/8923485
Publikováno v:
Biology and Physiology of the Blood-Brain Barrier ISBN: 9781475794915
Nicotine is a toxic substance which because of its lipid solubility can cross the blood brain barrier. It has several different actions in the CNS; one of which is neuroexcitation, where it can result in seizure activity. Based on the observations th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7773080717c1c33d392b70f18bf9c681
https://doi.org/10.1007/978-1-4757-9489-2_54
https://doi.org/10.1007/978-1-4757-9489-2_54
Autor:
J.-M. Lefauconnier
Publikováno v:
Physiology and Pharmacology of the Blood-Brain Barrier ISBN: 9783642768965
Transport of amino acids is very important for brain function as some of them are the precursors of neurotransmitters (serotonin, catecholamines, histamine) and of small polypeptides, and they participate in protein synthesis which is very active in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d40425d3bcdd98c57c5190a3e7baa47
https://doi.org/10.1007/978-3-642-76894-1_5
https://doi.org/10.1007/978-3-642-76894-1_5
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 5:318-326
Rats were made hypothyroid by a daily subcutaneous injection of propylthiouracil beginning the first day after birth. CBF, brain plasma volume, blood-brain extraction, and influx of some neutral amino acids were studied in 16-day-old animals. In hypo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::309ed4f9993f51e52dc3b0750292cd47
https://doi.org/10.1038/jcbfm.1985.41
https://doi.org/10.1038/jcbfm.1985.41
Publikováno v:
Experientia. 39(9)
Lead levels in the nervous system of rats intoxicated for 8 months by lead acetate (0.2% in drinking water) varied according to the region: the lowest levels were observed in sciatic nerve and the highest in hippocampus and cerebral neocortex, while
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ede97a13095c4ad4d322579e880891
https://pubmed.ncbi.nlm.nih.gov/6884491
https://pubmed.ncbi.nlm.nih.gov/6884491
Publikováno v:
Neurotoxicology. 8(4)
The present studies were undertaken to investigate the in vitro effects of mercuric chloride (HgCl2) and methylmercury chloride (CH3HgCl) on the uptake of [3H]alanine, [3H]phenylalanine, [3H]glutamic acid, [14C]alpha-methylamino-isobutyric acid, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4fdf299b83e1a265244adc8b7190a4cf
https://pubmed.ncbi.nlm.nih.gov/3441317
https://pubmed.ncbi.nlm.nih.gov/3441317
Publikováno v:
Archives internationales de physiologie et de biochimie. 97(5)
The influence of neonatal hypo- and hyperthyroidism on different aspects of tyrosine metabolism in the hypothalamus, striatum, brainstem, adrenal glands, heart and brown adipose tissue (BAT) were studied in 14-day old rats. The synthesis rate of cate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0ec73a2f9b4146dc945231407862ed
https://pubmed.ncbi.nlm.nih.gov/2480086
https://pubmed.ncbi.nlm.nih.gov/2480086
Limbic Seizures Induced by Systemically Applied Kainic Acid: How Much Kainic Acid Reaches the Brain?
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781468479737
Systemic or intracerebral injection of the neurotoxin kainic acid (KA) in rats induces a limbic seizure and brain damage syndrome, which has been proposed as an experimental animal model for human temporal lobe epilepsy (Nadler, 1981; Ben-Ari, 1985).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a1dd034d7065763f6ca567542eb9d2f
https://doi.org/10.1007/978-1-4684-7971-3_15
https://doi.org/10.1007/978-1-4684-7971-3_15