Výsledky vyhledávání - "J. M. Kaplow"

Ligand-induced transphosphorylation between different FGF receptors

Autor: Francoise Bellot, Gregg Crumley, J. M. Kaplow, Michael Jaye, Craig A. Dionne, Joseph Schlessinger

Publikováno v: The EMBO Journal. 10:2849-2854

Recent evidence shows that different fibroblast growth factors (FGF) bind with similar high affinities to two FGF receptors (FGFR) called flg and bek. In order to explore the mechanism of FGFR tyrosine autophosphorylation, we have generated cell line

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fcbf4171bf15279f124bae326af2ddf
https://doi.org/10.1002/j.1460-2075.1991.tb07834.x

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Induction of heat shock protein 70 by herbimycin A and cyclopentenone prostaglandins in smooth muscle cells

Autor: Linda Hamel, Mark H. Perrone, Kenneth L. Clark, Asher Zilberstein, Margaret Kenney, Al Spada, Camilo J. Rojas, J. M. Kaplow, Ali Ardati, Zaid Jayyosi, Linda Merkel

Publikováno v: Cell stresschaperones. 5(2)

This study characterizes Hsp70 induction in human smooth muscle cells (SMC) by herbimycin A and cyclopentenone prostaglandins. The magnitude of Hsp70 induction by cyclopentenone prostaglandins was 8- to 10-fold higher than induction by herbimycin A.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::953ff0290f0467c0ea73c1bc34d85ef2
https://pubmed.ncbi.nlm.nih.gov/11147963

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Monocyte chemoattractant protein-2 is a potent agonist of CCR2B

Autor: Robert J. Williams, Michael Jaye, Kuni Naik, Sandra W. Castro, J. M. Kaplow, Robert D. Pleass, Carolyn N. Lynch, Una M. Moore, Steven Daly, Alan Geoffrey Roach

Publikováno v: Journal of leukocyte biology. 62(6)

The binding and functional activity of the CC chemokines monocyte chemoattractant protein-1 (MCP-1), MCP-2, and MCP-3 have been characterized using Chinese hamster ovary DXB-11 cells transfected with the chemokine receptor CCR2B. Receptor binding stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dedc5f780206feed79ba53c5198ca24
https://pubmed.ncbi.nlm.nih.gov/9400834

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Ligand-binding specificity of human fibroblast growth factor receptor-3 IIIc

Autor: Michael Jaye, J. M. Kaplow, Hsien-Yi Lin, Michael J. Hayman

Publikováno v: FEBS letters. 411(2-3)

Earlier studies indicated that human fibroblast growth factor receptor (FGFR)-3IIIc was activated equally well by both FGF-1 and FGF-2. In contrast, murine FGFR-3IIIc was preferentially activated by FGF-1. To address this issue, we determined the lig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e80f5e45af8ab8aabfe1b3a775f89b52
https://pubmed.ncbi.nlm.nih.gov/9271242

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High-affinity binding and activation of a truncated FGF receptor by both aFGF and bFGF

Autor: G, Crumley, F, Bellot, J M, Kaplow, J, Schlessinger, M, Jaye, C A, Dionne

Publikováno v: Oncogene. 6(12)

We recently reported the cloning and overexpression of full-length forms of human fibroblast growth factor (FGF) receptors, bek and flg. These receptors contain three immunoglobulin (Ig)-like domains and an unusual acidic motif in the extracellular r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::366eda368e0edea102a0a93a0b1892d7
https://pubmed.ncbi.nlm.nih.gov/1722570

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Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factors

Autor: Michael Jaye, Ruta M, G. Searfoss, Francoise Bellot, Joseph Schlessinger, Craig A. Dionne, Gregg Crumley, J. M. Kaplow, Wilson H. Burgess

Publikováno v: The EMBO journal. 9(9)

The fibroblast growth factor (FGF) family consists of at least seven closely related polypeptide mitogens which exert their activities by binding and activation of specific cell surface receptors. Unanswered questions have been whether there are mult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d14ebb2d1ac4800a82c82e3f6f6e92
https://pubmed.ncbi.nlm.nih.gov/1697263

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Receptor for acidic fibroblast growth factor is related to the tyrosine kinase encoded by the fms-like gene (FLG)

Autor: Ruta M, David Givol, Jay S. Epstein, Joseph Schlessinger, C Dionne, J. M. Kaplow, M Jaye, Wilson H. Burgess, N Neiger, Gregg Crumley

We have previously isolated a human gene from an endothelial cell cDNA library encoding a putative tyrosine kinase; we have designated this gene the fms-like gene (FLG). To analyze the gene product(s) of FLG, we have generated rabbit polyclonal antib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257a53ffb464d7d20cd4b1f5f7fefdd5
https://europepmc.org/articles/PMC298360/

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Expression of mitogenically active human recombinant platelet-derived growth factor A-chain

Autor: J M, Kaplow, B D, Tong, D R, Hurwitz, M, Jaye

Publikováno v: Molecular biologymedicine. 6(3)

Expression vectors encoding cDNAs for the human platelet-derived growth factor (PDGF) A-chain (pJKl) and murine dihydrofolate reductase (pTKDHFR) were cotransfected into dihydrofolate reductase-deficient Chinese hamster ovary cells. Methotrexate-indu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::78e34e10787a044ca8f231092aba3e09
https://pubmed.ncbi.nlm.nih.gov/2482405

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