Zobrazeno 1 - 10
of 10
pro vyhledávání: '"J. M. Humphray"'
Autor:
K T, Bunce, N M, Clayton, R A, Coleman, E W, Collington, H, Finch, J M, Humphray, P P, Humphrey, J J, Reeves, R L, Sheldrick, R, Stables
Publikováno v:
Advances in prostaglandin, thromboxane, and leukotriene research.
Publikováno v:
Alimentary pharmacologytherapeutics. 4
Gastric secretory responses to histamine were investigated in anaesthetized dogs following treatment with oral ranitidine at 5 mg/kg twice daily for 358 weeks, and in isolated gastric mucosae from mice receiving sufotidine 240-280 mg.kg/day for 15 mo
Publikováno v:
Agents and Actions. 11:167-170
Gastric mucosal lesions were produced in rats by dosing orally with aspirin, 300 mg/kg. Predosing orally with either ranitidine or cimetidine inhibited this lesion formation; the respective ED50 values were 0.8 and 3.9 mg/kg p.o. Oral ranitidine also
Publikováno v:
Agents and Actions. 13:166-169
The antisecretory potency and duration of action of the new histamine H2-receptor antagonist AH 22216 have been compared with those of cimetidine, ranitidine and SK & F 93479 against histamine-induced gastric acid secretion in the conscious Heidenhai
Publikováno v:
Agents and Actions. 11:160-164
The H2-receptor antagonists ranitidine and cimetidine were tested against gastric secretory dose-response curves to histamine, pentagastrin and bethanechol in the Heidenhain-pouch dog. Histamine-induced gastric secretion was antagonized in a competit
Publikováno v:
British Journal of Pharmacology. 72:55-60
1 The new H2-receptor antagonist, ranitidine, has been compared with cimetidine as an inhibitor of gastric acid secretion in the anaesthetized dog. 2 Both ranitidine and cimetidine given intravenously inhibited histamine-induced gastric secretion in
Publikováno v:
Agents and actions. 12(1-2)
Cumulative concentration-response curves to histamine or dimaprit were constructed on guinea-pig isolated right atria and agonist dose-ratios were determined following addition of ranitidine, cimetidine, metiamide or tiotidine alone or a combination
1 Ranitidine has been investigated as an antagonist of the H2-receptor-mediated responses to histamine of guniea-pig atrium and rat uterus in vitro and as an inhibitor of gastric acid secretion in the rat. 2 Ranitidine competitively antagonized hista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa1f0e2dfc143fd2a352c8b22f14fa16
https://europepmc.org/articles/PMC2071551/
https://europepmc.org/articles/PMC2071551/
The new H2-receptor antagonist, ranitidine, has been compared with cimetidine and metiamide as an inhibitor of gastric acid secretion in the dog. All three compounds were effective both intravenously or by mouth in inhibiting secretion induced by his
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2fd3cb198665c7032841c8103df3045
https://europepmc.org/articles/PMC1419083/
https://europepmc.org/articles/PMC1419083/
Publikováno v:
British journal of pharmacology. 76(3)
1 The H2-receptor antagonists, ranitidine and cimetidine, have been compared with atropine and pirenzepine for their effects on gastric acid output, and on salivary secretion from the left parotid gland in the anaesthetized dog. Gastric and salivary