Zobrazeno 1 - 10
of 91
pro vyhledávání: '"J. M. Harlan"'
Autor:
R. K. Winn, J. M. Harlan
Publikováno v:
Journal of Thrombosis and Haemostasis. 3:1815-1824
The integrity of the endothelial lining of the vasculature is essential for vascular homeostasis and normal organ function. Endothelial injury or dysfunction has been implicated in the pathogenesis of diverse vascular diseases. Studies in vitro have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab3f24a80a214e1ce91e368a34b32a63
https://doi.org/10.1111/j.1538-7836.2005.01378.x
https://doi.org/10.1111/j.1538-7836.2005.01378.x
Publikováno v:
Scandinavian Journal of Immunology. 56:588-592
Background: Both C1-inhibitor (C1-INH) and antibodies against the CD18 adhesion molecule have been shown to reduce ischaemia–reperfusion injuries. The objective of this study was to investigate the effect of increased ischaemia times and to determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2a455d3f910858fcd26e178c6fe7a0c
https://doi.org/10.1046/j.1365-3083.2002.01173.x
https://doi.org/10.1046/j.1365-3083.2002.01173.x
Publikováno v:
Blood. 92:2759-2765
The effect of lipopolysaccharide (LPS) on endothelial cells is a key component of the inflammatory response seen in Gram-negative sepsis. LPS does not cause death of cultured human endothelial cells. However, when the expression of new proteins is in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce7bcc05351217035182824ff0918dba
https://doi.org/10.1182/blood.v92.8.2759.420k29_2759_2765
https://doi.org/10.1182/blood.v92.8.2759.420k29_2759_2765
Publikováno v:
The Journal of Immunology. 159:943-951
E-selectin (CD62E) is a cytokine-inducible endothelial cell adhesion molecule that tethers polymorphonuclear leukocytes (PMNs) and supports PMN rolling under conditions of flow. We examined whether interaction of PMNs with E-selectin also leads to ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77953a29f2f9813028b1a202444446b4
https://doi.org/10.4049/jimmunol.159.2.943
https://doi.org/10.4049/jimmunol.159.2.943
Publikováno v:
The Journal of Immunology. 157:2555-2563
Neutrophil (PMN) recruitment into systemic inflammatory sites in vivo is thought to be initiated by selectin-mediated endothelial adherence. We explored the role of L-selectin (CD62L) in leukocyte emigration following instillation of bacteria into th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d54841b8a2ac08aa8a3d0f91a0c913c
https://doi.org/10.4049/jimmunol.157.6.2555
https://doi.org/10.4049/jimmunol.157.6.2555
Autor:
M. L. Phillips, J M Harlan, Robert Bayer, A Etzioni, H D Ochs, B R Schwartz, James C. Paulson
Publikováno v:
Journal of Clinical Investigation. 96:2898-2906
We have previously reported a newly discovered congenital disorder of neutrophil adhesion, leukocyte adhesion deficiency syndrome type 2 (LAD II). The clinical manifestations of this syndrome are similar to those seen in the classic leukocyte adhesio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc96d5d9f04011742f7bc093ee29bcd6
https://doi.org/10.1172/jci118361
https://doi.org/10.1172/jci118361
Publikováno v:
The Journal of Immunology. 155:4011-4015
Ischemia-reperfusion injury in the rabbit ear is neutrophil (PMN)-mediated, and is significantly reduced by anti-adhesion agents directed against beta 2 integrins, P-selectin, or L-selectin. We further examined selectin-mediated adherence in this set
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23fcd111f02f6c3bd72853531e0b5425
https://doi.org/10.4049/jimmunol.155.8.4011
https://doi.org/10.4049/jimmunol.155.8.4011
Autor:
T M, Carlos, J M, Harlan
Publikováno v:
Blood. 84:2068-2101
In the 9 years since the last review on leukocyte and endothelial interactions was published in this journal many of the critical structures involved in leukocyte adherence to and migration across endothelium have been elucidated. With the advent of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974a1794acfe6b09319624a722ab9e8a
https://doi.org/10.1182/blood.v84.7.2068.2068
https://doi.org/10.1182/blood.v84.7.2068.2068
Publikováno v:
The Journal of Immunology. 153:2234-2238
mAb blockade of CD18-mediated neutrophil adherence has previously been shown to reduce tissue injury in the rabbit ear as a result of ischemia followed by reperfusion. Similar injury reduction has been demonstrated whether treatment is given before i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7edaa0cf267730ab7e908a3c33d95024
https://doi.org/10.4049/jimmunol.153.5.2234
https://doi.org/10.4049/jimmunol.153.5.2234