Zobrazeno 1 - 10
of 18
pro vyhledávání: '"J. M. Gidday"'
Publikováno v:
Journal of Molecular and Cellular Cardiology. 24:351-364
Rapid steady-state estimates of interstitial fluid (ISF) adenosine concentrations (ADOi) in the left ventricular epicardium of anesthetized dogs were obtained by the epicardial porous disc (EPD) method described herein. Because of the high temporal a
Publikováno v:
Journal of Molecular and Cellular Cardiology. 24:347-350
Publikováno v:
Annals of neurology. 48(3)
Hypoxia-inducible factor-1 (HIF-1) is a heterodimer composed of HIF-1alpha and HIF-1beta protein subunits. This transcription factor is essential for the activation of hypoxia-inducible genes like erythropoietin, some glucose transporters, the glycol
Autor:
J M, Gidday, Y, Zhu
Publikováno v:
Current eye research. 17(8)
Little is known regarding the status and implications of altered retinal blood flow (RBF) following a period of temporary retinal ischemia. We undertook studies to measure acute changes in RBF after ischemia, and the mechanisms responsible for mediat
Publikováno v:
Investigative ophthalmologyvisual science. 37(13)
The authors and others have shown previously that the purine nucleoside adenosine is a potent vasodilator in the retinal microcirculation, mediating increases in retinal blood flow (RBF) in response to several autoregulatory stimuli. The current expe
Publikováno v:
Brain research. 734(1-2)
Cerebral ischemia is often followed by a period of delayed hypoperfusion that may contribute to tissue injury. We tested the hypothesis that augmentation of interstitial adenosine can improve tissue perfusion under this condition 10 min global ischem
Autor:
Y, Zhu, J M, Gidday
Publikováno v:
Investigative ophthalmologyvisual science. 37(1)
To determine whether retinal blood flow increases in response to perinatal hypoglycemia and whether the vasodilator adenosine is involved in mediating the hyperemic response.Retinal fluorescein videoangiography was undertaken in intact eyes of isoflu
Publikováno v:
The American journal of physiology. 265(5 Pt 2)
The present study tested the hypothesis that adenosine is involved in mediating the hyperemic response of the newborn brain to hypoglycemia. By use of the cranial window and microdialysis-H2 clearance methodologies, changes in the diameter of pial ar
Autor:
J M, Gidday, T S, Park
Publikováno v:
Investigative ophthalmologyvisual science. 34(9)
To determine if the purine vasodilator adenosine participates in mediating autoregulatory dilations of the retinal microcirculation in vivo.The retinal microcirculation of isoflurane-anesthetized newborn pigs was observed by videomicroscopy (x310). S
Autor:
J. M. Gidday, C. L. Phillips, Rafael Rubio, C. S. Tietjan, Robert M. Berne, Curtis G. Tribble, Luiz Belardinelli
Publikováno v:
The American journal of physiology. 259(5 Pt 2)
Epicardial porous disks were used to estimate left ventricular interstitial fluid adenosine in the isolated guinea pig heart perfused at constant flow. To validate this technique, adenosine was infused with 0.5 microM dipyridamole and 5 microM erythr