Výsledky vyhledávání - "J. M. G. Davis"

CHRONIC INHALATION STUDIES OF TWO TYPES OF STONE WOOL FIBERS IN RATS

Autor: E. E. McConnell, O. Kamstrup, J. M. G. Davis, J. Chevalier, P. Thevenaz, A. Ellehauge

Publikováno v: Inhalation Toxicology. 13:603-621

A summary is given of the pathology results after long-term inhalation in rats of insulation wool representing the new biosoluble types. The pathology results are compared with previously conducted long-term inhalation study with MMVF21 (traditional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7019fd40b2f75af8cc271ffe24020a9a
https://doi.org/10.1080/08958370118075

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The Biopersistence and Pathogenicity of Man-made Vitreous Fibres after Short- and Long-term Inhalation

Autor: O. Kamstrup, M. Guldberg, A. Ellehauge, J. M. G. Davis

Publikováno v: The Annals of Occupational Hygiene. 42:191-199

A summary is given of the biopersistence and pathology after inhalation by rats of two different Man–made Vitreous Fibres, MMVF10 (traditional stone wool) and MMVF23 (HT stone wool), and the results are discussed in relation to biopersistence measu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e03feb60c59ed4da18ef7f44a80e4f34
https://doi.org/10.1016/s0003-4878(98)00019-2

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Short-term inhalation and in vitro tests as predictors of fiber pathogenicity

Autor: Ken Donaldson, J. M. G. Davis, Brian G. Miller, David M. Brown, R. T. Cullen

Publikováno v: Environmental Health Perspectives

A wide range of fiber types was tested in two in vitro assays: toxicity to A549 epithelial cells, as detachment from substrate, and the production of the proinflammatory cytokine tumor necrosis factor (TNF) by rat alveolar macrophages. Three of the f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50515e82761d994f6d91029820b018c8
http://europepmc.org/articles/PMC1470121

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Assessment of the toxicity of man-made fibres *1A final report of a workshop held in Paris, France 3?4 February 1994

Autor: R. Brown, Patrick Brochard, G. Gibbs, Jean Bignon, M. Greim, Günter Oberdörster, Patrick Sebastien, V. Vu, J. M. G. Davis

Publikováno v: The Annals of Occupational Hygiene. 39:89-106

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::32e6f8ba2143383083b7dc872e7e3dc3
https://doi.org/10.1016/0003-4878(94)00126-l

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Studies on the morphological patterns of asbestos induced mesotheliomas in vivo and in vitro

Autor: Ken Donaldson, R E Bolton, I. P. Gormley, J. M. G. Davis, G. M. Brown

Publikováno v: Carcinogenesis. 1(3)

Cell lines were established in vitro from five peritoneal mesotheliomas produced in rats by the injection of crocidolite asbestos. These tumours exhibited the previously described diverse range of histological patterns normally associated with mesoth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9be6ac1470a705f45710f001933d09
https://pubmed.ncbi.nlm.nih.gov/22283003

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The role of clearance and dissolution in determining the durability or biopersistence of mineral fibers

Autor: J. M. G. Davis

Publikováno v: Environmental Health Perspectives

It is generally accepted that to cause pulmonary disease, mineral fibers must be relatively long and thin but also able to remain in the lung for long periods. This "biopersistence" of fibers is limited by two main mechanisms of fiber clearance: remo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299e8e1082f17e777f7917cdea463fea
https://doi.org/10.1289/ehp.94102s5113

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The need for standardised testing procedures for all products capable of liberating respirable fibres: the example of materials based on cellulose

Autor: J. M. G. Davis

Publikováno v: Occupational and Environmental Medicine. 50:187-190

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::745fff4fe1a150f23300a9c5cc493995
https://doi.org/10.1136/oem.50.2.187

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The relationship between fibrosis and cancer in experimental animals exposed to asbestos and other fibers

Autor: H. Cowie, J. M. G. Davis

Publikováno v: Environmental Health Perspectives

The association between occupational asbestos exposure and the development of both pulmonary fibrosis or asbestosis and pulmonary carcinomas is well documented. It has been suggested that the two pathological conditions are associated with asbestos-r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b24f4a7515778c750d3ec5cdcf7d8c3
https://doi.org/10.1289/ehp.9088305

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Impaired chemotactic responses of bronchoalveolar leukocytes in experimental pneumocniosis

Autor: M. D. Robertson, Ken Donaldson, J. M. G. Davis, J Slight, G. M. Brown, David M. Brown

Publikováno v: The Journal of Pathology. 160:63-69

Rats were exposed to clouds of the following pneumoconiotic dusts: quartz, coal-mine dust, and chrysotile asbestos at 10 or 50 mg/m3 for 8, 32, and 75 days; for comparison, rats were also exposed to the non-pathogenic dust titanium dioxide (TiO2). Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284d4bb7b44aa09a8e3c77ed0bf39a61
https://doi.org/10.1002/path.1711600113

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