Výsledky vyhledávání - "J. M. Dressler"

Severe folate restriction results in depletion of and alteration in the composition of the intracellular folate pool, moderate sensitization to methotrexate and trimetrexate, upregulation of endogenous DHFR activity, and overexpression of metallothionein

Autor: Z. Chen, D. G. Priest, M. Bunni, J. L. DiCapua, Peter W. Melera, Wei-Yong Zhu, J. M. Dressler

Publikováno v: Journal of Experimental Therapeutics and Oncology. 2:264-277

DC-3F/FA3 cells (FA3) were derived from antifolate-sensitive CHL cells by selection for growth in folate-free media containing 15 pM [6S]-5CHOFH4. These cells undergo a 30-fold decrease in intracellular folates, overexpress folate receptor alpha (FR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7171d73dae56f4ac40283351b6995f3
https://doi.org/10.1046/j.1359-4117.2002.01049.x

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