Zobrazeno 1 - 10
of 18
pro vyhledávání: '"J. M. Croop"'
Autor:
E. Buschman, Mingxin Che, Philippe Gros, I. M. Arias, J. M. Croop, D. E. Housman, R. J. Arceci
Publikováno v:
Journal of Biological Chemistry. 267:18093-18099
We have produced antibodies specific for the three P-glycoprotein (P-gp) isoforms encoded by the mouse mdr1, mdr2, and mdr3 genes. The anti-Mdr2 and anti-Mdr3 antibodies were generated against synthetic peptides derived from the "linker" region, wher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5a8ec2f2a7d499908d109bb4d80a4c1
https://doi.org/10.1016/s0021-9258(19)37157-1
https://doi.org/10.1016/s0021-9258(19)37157-1
Publikováno v:
Molecular and Cellular Biology. 11:3940-3948
Mammalian multidrug-resistant cell lines, selected for resistance to a single cytotoxic agent, display cross-resistance to a broad spectrum of structurally and functionally unrelated compounds. These cell lines overproduce a membrane protein, the P-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4182bd1e088ec09721666cff337b2aed
https://doi.org/10.1128/mcb.11.8.3940
https://doi.org/10.1128/mcb.11.8.3940
Autor:
I, Bosch, J M, Croop
Publikováno v:
Cytotechnology. 27(1-3)
Analysis of multidrug resistant cell lines has led to the identification of the P-glycoprotein multigene family. Two of the three classes of mammalian P-glycoproteins have the ability to confer cellular resistance to a broad range of structurally and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fd60da6995f31097a065594ff3f7b8fc
https://pubmed.ncbi.nlm.nih.gov/19002778
https://pubmed.ncbi.nlm.nih.gov/19002778
Autor:
J M, Croop
Publikováno v:
Methods in enzymology. 292
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::414b9551b31a6e8bd6dd45b2e16218aa
https://pubmed.ncbi.nlm.nih.gov/9711549
https://pubmed.ncbi.nlm.nih.gov/9711549
Publikováno v:
Biology of reproduction. 58(2)
Polycystic ovaries (PCO) can be induced in prepubertal rats by daily injection of dehydroepiandrosterone (DHEA). There are high levels of progesterone, androgens, and estrogens in the cystic fluid of DHEA-treated rat ovaries. The purpose of this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d33240f8ca40fddecebc4b38edae384b
https://pubmed.ncbi.nlm.nih.gov/9475386
https://pubmed.ncbi.nlm.nih.gov/9475386
Publikováno v:
Blood. 91(1)
In an attempt to explore novel treatment modalities in acute myeloid leukemia (AML), we studied the role of costimulatory and cytokine gene immunotherapy in murine AML. We have previously shown that leukemic mice can be cured with CD80 transfected le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::12ae4192dae825b8c9dc2dfc83dcdf29
https://pubmed.ncbi.nlm.nih.gov/9414288
https://pubmed.ncbi.nlm.nih.gov/9414288
Publikováno v:
Cancer research. 58(2)
The P-glycoprotein is an energy-dependent efflux pump capable of decreasing the intracellular concentration of a broad range of chemotherapeutic agents. [99mTc]Sestamibi, a P-glycoprotein transport substrate, is a sensitive probe of P-glycoprotein fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de8b9388a9e5e3b2e561a5e4b3aa1327
https://pubmed.ncbi.nlm.nih.gov/9443405
https://pubmed.ncbi.nlm.nih.gov/9443405
Publikováno v:
Blood. 89(8)
We have previously shown in a murine acute myelogenous leukemia (AML) model that leukemic mice can be cured with a B7 vaccine if immunized early in the disease and that CD8+ T cells are necessary for tumor rejection. However, when B7 vaccine is admin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fd6c5a29df05d155a60d8fdc7aca934e
https://pubmed.ncbi.nlm.nih.gov/9108412
https://pubmed.ncbi.nlm.nih.gov/9108412
Autor:
K, Dunussi-Joannopoulos, H J, Weinstein, P W, Nickerson, T B, Strom, S J, Burakoff, J M, Croop, R J, Arceci
Publikováno v:
Blood. 87(7)
Recent studies have shown that tumor cells genetically modified by transduction of B7-1, a natural ligand for the T-cell costimulatory molecules CD28 and CTLA-4, are rejected in syngeneic hosts. In these reports, transformed cell lines and drug-selec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f7894a7a89438810a13e0a71887998f4
https://pubmed.ncbi.nlm.nih.gov/8639914
https://pubmed.ncbi.nlm.nih.gov/8639914
Publikováno v:
Cancer research. 53(5)
The multidrug-resistant P-glycoprotein (Pgp), a M(r) 170,000 plasma membrane protein encoded by the mammalian multidrug resistance gene (MDR1), appears to function as an energy-dependent efflux pump. Many of the drugs that interact with Pgp are lipop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::513223c7bbbba2fa9e43372e39d3cf3f
https://pubmed.ncbi.nlm.nih.gov/8094997
https://pubmed.ncbi.nlm.nih.gov/8094997