Zobrazeno 1 - 5
of 5
pro vyhledávání: '"J. M. Bilotta"'
Publikováno v:
Inhalation Toxicology. 3:339-351
The toxicity of cadmium sulfate (CdSO4) aerosol was investigated using rat nasal turbinate epithelium to provide in vivo tissue sensitivity data for comparison with data obtained previously for rat and human nasal turbinate epithelial cells exposed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d3e5b29af81483e2352275781235988
https://doi.org/10.3109/08958379109145293
https://doi.org/10.3109/08958379109145293
Autor:
M W, Lutz, P H, Morgan, M K, James, P L, Feldman, M F, Brackeen, A P, Lahey, S V, James, J M, Bilotta, J C, Pressley
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 271(2)
A simple mathematical model of analgesia in the rat is developed and utilized to determine quantitative structure-activity relationships for a series of novel 4-anilidopiperidine opioids. The compounds tested (selected alkyl carboxyethyl esters attac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09162fc4202b30cfa9d52e5ca23f9a29
https://pubmed.ncbi.nlm.nih.gov/7965798
https://pubmed.ncbi.nlm.nih.gov/7965798
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 259(2)
GI 87084B (3-[4-methoxycarbonyl-4-[(1-oxopropyl) phenylamino]1-piperidine]propanoic acid, methyl ester, hydrochloride) was found to be a potent opioid agonist in the guinea pig ileum (EC50 = 2.4 +/- 0.6 nM), the rat vas deferens (EC50 = 387 +/- 44 nM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8db42cd1602391c459d79742fdf4290a
https://pubmed.ncbi.nlm.nih.gov/1658308
https://pubmed.ncbi.nlm.nih.gov/1658308
Autor:
A P Lahey, S V Schuster, Paul L. Feldman, Marcus F. Brackeen, H J Leighton, Michael K. James, Michael W. Lutz, M R Johnson, J M Bilotta
Publikováno v:
Journal of medicinal chemistry. 34(7)
In an effort to discover a potent ultrashort-acting mu opioid analgetic that is capable of metabolizing to an inactive species independent of hepatic function, several classes of 4-anilidopiperidine analgetics were synthesized and evaluated. One seri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4485ede6c6c1b14551348d53eb1a5c48
https://pubmed.ncbi.nlm.nih.gov/2066993
https://pubmed.ncbi.nlm.nih.gov/2066993
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 4(2)
Differences in the sensitivity of human and Fischer 344 rat tissues to cadmium sulphate (CdSO4) toxicity were investigated in an in vitro model using human and rat nasal turbinate epithelial (NTE) cells. Both rat and human NTE cells were obtained fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e63872f0ea7bfd8607d5a444dddebb9c
https://pubmed.ncbi.nlm.nih.gov/20702272
https://pubmed.ncbi.nlm.nih.gov/20702272