Výsledky vyhledávání - "J. M. Barnett"

Akademický článek

Prebiotic fibre mixtures counteract the manifestation of gut microbial dysbiosis induced by the chemotherapeutic 5-Fluorouracil (5-FU) in a validated in vitro model of the colon

Autor: Janine Ziemons, Lars E. Hillege, Romy Aarnoutse, Judith de Vos-Geelen, Liselot Valkenburg-van Iersel, Jasper Mastenbroek, Robin van Geel, David J. M. Barnett, Sander S. Rensen, Ardy van Helvoort, Lotte H. J. Dopheide, Guus Roeselers, John Penders, Marjolein L. Smidt, Koen Venema

Publikováno v: BMC Microbiology, Vol 24, Iss 1, Pp 1-17 (2024)

Abstract Background 5-Fluorouracil (5-FU) is used as an antineoplastic agent in distinct cancer types. Increasing evidence suggests that the gut microbiota might modulate 5-FU efficacy and toxicity, potentially affecting the patient’s prognosis. Th

Externí odkaz: https://doaj.org/article/8c054ca32f3b4fc89ee48efa04a62aa6

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Akademický článek

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Akademický článek

Seeding and feeding milestones: the role of human milk microbes and oligosaccharides in the temporal development of infant gut microbiota

Autor: Martha F. Endika, David J. M. Barnett, Cynthia E. Klostermann, Noortje Kok, Henk A. Schols, Arjen Nauta, Ilja C. W. Arts, John Penders, Koen Venema, Hauke Smidt

Publikováno v: Gut Microbiome, Vol 5 (2024)

Breastfeeding represents a strong selective factor for shaping the infant gut microbiota. Besides providing nutritional requirements for the infant, human milk is a key source of oligosaccharides, human milk oligosaccharides (HMOs), and diverse micro

Externí odkaz: https://doaj.org/article/1c5c10e62ed94ef1b55a83f47bc3edf5

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Akademický článek

Microbiota-dependent influence of prebiotics on the resilience of infant gut microbiota to amoxicillin/clavulanate perturbation in an in vitro colon model

Autor: Martha F. Endika, David J. M. Barnett, Cynthia E. Klostermann, Henk A. Schols, Ilja C. W. Arts, John Penders, Arjen Nauta, Hauke Smidt, Koen Venema

Publikováno v: Frontiers in Microbiology, Vol 14 (2023)

Antibiotic exposure disturbs the developing infant gut microbiota. The capacity of the gut microbiota to recover from this disturbance (resilience) depends on the type of antibiotic. In this study, infant gut microbiota was exposed to a combination o

Externí odkaz: https://doaj.org/article/9af2fdd82bb040c7a784cdc54190e810

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