Zobrazeno 1 - 9
of 9
pro vyhledávání: '"J. M. Anchin"'
Autor:
Paul A. Ramsland, Lin Shan, Allen B. Edmundson, D. S. Linthicum, Zhao-chang Fan, J. M. Anchin, Luke W. Guddat, C. Broomell
Publikováno v:
Journal of Molecular Biology. 302:853-872
The three-dimensional structure of a complex of an Fab from a murine IgG2b(lambda) antibody (NC10.14) with a high potency sweet tasting hap- ten, N-(p-cyanophenyl)-N'-(diphenylmethyl)-N"-(carboxymethyl)guan idine (NC174), has been determined to 2.6 A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b197194b3a359b02182c9a54b7fed947
https://doi.org/10.1006/jmbi.2000.4083
https://doi.org/10.1006/jmbi.2000.4083
Publikováno v:
The Journal of Immunology. 153:3059-3069
The interactive residues for mouse mAb NC10.8, which binds a superpotent guanidinium sweetener N-(p-cyanophenyl)-N'-(diphenylmethyl)guanidinoacetic acid with high affinity (Kd = 5 nM), were examined by using radioligand competitive binding, photoaffi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea0ab41a3f331e5a923160b1034d80f5
https://doi.org/10.4049/jimmunol.153.7.3059
https://doi.org/10.4049/jimmunol.153.7.3059
Autor:
A. Thakur, Yasmin Thanavala, Hong Shi, Michael W. Pride, J. M. Anchin, Philip T. LoVerde, D. S. Linthicum
Publikováno v:
Proceedings of the National Academy of Sciences. 89:11900-11904
Monoclonal antibody 2F10 is an "internal-image" anti-idiotype (anti-id) antibody capable of mimicking the group-specific "a" determinant of human hepatitis B surface antigen (HBsAg). By mRNA sequencing and computer-assisted molecular modeling of mono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e4918bcb4a07a10ed2b71ec30a02dc
https://doi.org/10.1073/pnas.89.24.11900
https://doi.org/10.1073/pnas.89.24.11900
Publikováno v:
The Journal of Immunology. 146:4248-4257
The structural features of mAb directed against the opiate morphine were analyzed by using competitive ligand analog-binding studies, examination of the V region amino acid sequence, and computer-aided molecular modeling of the fragment V region. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cee66288d065f61e40ec4131cdde7d64
https://doi.org/10.4049/jimmunol.146.12.4248
https://doi.org/10.4049/jimmunol.146.12.4248
Publikováno v:
Combinatorial chemistryhigh throughput screening. 4(5)
Several new aspects of computer-assisted molecular modeling strategies and biophysical techniques, such as fluorescence spectroscopy, circular dichroism, and absorption spectroscopy, have proved useful in the analysis and description of antibody-liga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33cb4dccecf9b6fd2a1373352712c1a2
https://pubmed.ncbi.nlm.nih.gov/11472232
https://pubmed.ncbi.nlm.nih.gov/11472232
Publikováno v:
Journal of molecular recognition : JMR. 10(5)
Monoclonal antibodies (mAb) made to the superpotent guanidino sweet tasting ligand, N-(p-cyanophenyl)-N'-(diphenylmethyl)-guanidineacetic acid were examined for their molecular recognition specificities using 14 different sweetener analogues in a com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4a221a0b9823b37c2605aac25fd31de
https://pubmed.ncbi.nlm.nih.gov/9587873
https://pubmed.ncbi.nlm.nih.gov/9587873
Autor:
P. R. Droupadi, J. M. Anchin, D. S. Linthicum, Shankar Subramaniam, Malini Viswanathan, Chhabinath Mandal
Monoclonal antibody NC6.8 binds the superpotent sweetener ligand N-(p-cyanophenyl)-N'-(diphenylmethyl) guanidineacetic acid with high affinity (Kd = 53 nM). Using computer-aided molecular modeling and several experimental techniques, such as competit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c51c5de8ed48fefcc94f2afde66eb90
https://europepmc.org/articles/PMC1236304/
https://europepmc.org/articles/PMC1236304/
Publikováno v:
Journal of molecular biology. 236(1)
Crystal structures of an Fab (NC6.8) from a murine IgG2b(κ) antibody and its complex with a sweet-tasting, N -,N′-,N″-trisubstituted guanidine compound (NC174) have been determined by X-ray analysis. Both crystal forms are produced by a microsee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36265fd36c7e66f23be775f27de9609f
https://pubmed.ncbi.nlm.nih.gov/7893280
https://pubmed.ncbi.nlm.nih.gov/7893280
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 146(12)
The structural features of mAb directed against the opiate morphine were analyzed by using competitive ligand analog-binding studies, examination of the V region amino acid sequence, and computer-aided molecular modeling of the fragment V region. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a2f84b82d0e3d66c7f8f1c4a48ed700
https://pubmed.ncbi.nlm.nih.gov/2040800
https://pubmed.ncbi.nlm.nih.gov/2040800