Zobrazeno 1 - 10
of 126
pro vyhledávání: '"J. Luis Guerrero"'
Autor:
Felicitas J. Detmer, Nathaniel M. Alpert, Sung-Hyun Moon, Maeva Dhaynaut, J. Luis Guerrero, Nicolas J. Guehl, Fangxu Xing, Pedro Brugarolas, Timothy M. Shoup, Marc D. Normandin, Matthieu Pelletier-Galarneau, Georges El Fakhri, Yoann Petibon
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Mitochondrial dysfunction plays a key role in doxorubicin-induced cardiotoxicity (DIC). In this proof-of-principle study, we investigated whether PET mapping of cardiac membrane potential, an indicator of mitochondrial function, could detect
Externí odkaz:
https://doaj.org/article/45f72c7eae84477dbaf9f917eb1916ed
Autor:
Zahra Alvandi, Yasufumi Nagata, Livia Silva Araúujo Passos, Ali Hashemi Gheinani, J. Luis Guerrero, Jill Wylie‐Sears, Dayana Carolina Romero, Brittan A. Morris, Suzanne M. Sullivan, Koushiar M. Yaghoubian, Amirhossein Alvandi, Rosalyn M. Adam, Elena Aikawa, Robert A. Levine, Joyce Bischoff
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 7 (2022)
Background The onset and mechanisms of endothelial‐to‐mesenchymal transition (EndMT) in mitral valve (MV) leaflets following myocardial infarction (MI) are unknown, yet these events are closely linked to stiffening of leaflets and development of
Externí odkaz:
https://doaj.org/article/f74bcb391dbb49d6ba7f1f73c032dd4c
Autor:
Yasufumi Nagata, Philippe B. Bertrand, Vinit Baliyan, Jonathan Kochav, Ruth D. Kagan, Kristian Ujka, Hassan Alfraidi, Antonia van Kampen, Jordan E. Morningstar, Jacob P. Dal-Bianco, Serguei Melnitchouk, Godtfred Holmvang, Michael A. Borger, Reece Moore, Lanqi Hua, Razia Sultana, Pablo Villar Calle, Brian Yum, J. Luis Guerrero, Tomas G. Neilan, Michael H. Picard, Jiwon Kim, Francesca N. Delling, Judy Hung, Russell A. Norris, Jonathan W. Weinsaft, Robert A. Levine
Publikováno v:
Circulation: Cardiovascular Imaging. 16
Background: The relation between ventricular arrhythmia and fibrosis in mitral valve prolapse (MVP) is reported, but underlying valve-induced mechanisms remain unknown. We evaluated the association between abnormal MVP-related mechanics and myocardia
Akademický článek
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Autor:
Nicolas J, Guehl, Matthieu, Pelletier-Galarneau, Dustin W, Wooten, J Luis, Guerrero, Aurélie, Kas, Marc D, Normandin, Georges El, Fakhri, Nathaniel M, Alpert
Publikováno v:
Circ Cardiovasc Imaging
BACKGROUND: We previously proposed a technique for quantitative measurement of rest and stress absolute myocardial blood flow (MBF) using a two-injection single-scan imaging session. Recently, we validated the method in a pig model for the long-lived
Autor:
J. Luis Guerrero, Anthony O. Caggiano, Douglas B. Sawyer, Erika L. Troy, Maya Srinivas, Ronald Zolty, Anindita Ganguly, Craig Hackett, Donald Button, Tom J. Parry, Andrea Vecchione, Jennifer Iaci
Publikováno v:
European Journal of Pharmacology. 796:76-89
Neuregulins are important growth factors involved in cardiac development and response to stress. Certain isoforms and fragments of neuregulin have been found to be cardioprotective. The effects of a full-length neuregulin-1β isoform, glial growth fa
Autor:
Marie-Claude Drolet, J. Luis Guerrero, Patrick Mathieu, Marie-Annick Clavel, Jonathan Beaudoin, Claudia Côté-Laroche, Ons Marsit, Marie Arsenault, Marie-Chloé Boulanger, Dae-Hee Kim, Robert A. Levine, Philipp E. Bartko, Elena Aikawa, Joyce Bischoff, Mark D. Handschumacher, Sandra Hadjadj, Marc-André Bouchard, Jacques Couet, Marine Clisson, Philippe Pibarot
Publikováno v:
Journal of the American College of Cardiology. 75(4)
Background Mitral leaflet enlargement has been identified as an adaptive mechanism to prevent mitral regurgitation in dilated left ventricles (LVs) caused by chronic aortic regurgitation (AR). This enlargement is deficient in patients with functional
Publikováno v:
Methods in Molecular Biology ISBN: 9781493985968
Ischemic mitral regurgitation (IMR) is a common complication of ischemic heart disease that doubles mortality after myocardial infarction and is a major driving factor increasing heart failure. IMR is caused by left ventricular (LV) remodeling which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c29550691d26f29a99930bf6097fe51
https://doi.org/10.1007/978-1-4939-8597-5_23
https://doi.org/10.1007/978-1-4939-8597-5_23
Autor:
Suzanne Sullivan, Mark D. Handschumacher, J. Luis Guerrero, Robert A. Levine, Gavin J. C. Braithwaite, Gus J. Vlahakes, Xin Zeng, James R. Stone, Judy Hung, Jorge Solis, Lin Zou, Orhun K. Muratoglu
Publikováno v:
JACC: Cardiovascular Interventions. 8:355-363
Objectives The aim of this study was to examine the chronic effects of polyvinyl-alcohol (PVA) injection on mitral regurgitation (MR) reduction, mitral valve geometry, and left ventricular (LV) remodeling in a chronic ischemic MR sheep model. Backgro
Akademický článek
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