Zobrazeno 1 - 10
of 436
pro vyhledávání: '"J. Lockett"'
Autor:
Robert Y. S. Cheng, Lisa A. Ridnour, Adelaide L. Wink, Ana L. Gonzalez, Elise L. Femino, Helene Rittscher, Veena Somasundaram, William F. Heinz, Leandro Coutinho, M. Cristina Rangel, Elijah F. Edmondson, Donna Butcher, Robert J. Kinders, Xiaoxian Li, Stephen T. C. Wong, Daniel W. McVicar, Stephen K. Anderson, Milind Pore, Stephen M. Hewitt, Timothy R. Billiar, Sharon A. Glynn, Jenny C. Chang, Stephen J. Lockett, Stefan Ambs, David A. Wink
Publikováno v:
Cell Death and Disease, Vol 14, Iss 5, Pp 1-12 (2023)
Abstract A strong correlation between NOS2 and COX2 tumor expression and poor clinical outcomes in ER breast cancer has been established. However, the mechanisms of tumor induction of these enzymes are unclear. Analysis of The Cancer Genome Atlas (TC
Externí odkaz:
https://doaj.org/article/5046eefbdac54f9198343a6b6f842146
Autor:
Veena Somasundaram, Lisa A. Ridnour, Robert YS. Cheng, Abigail J. Walke, Noemi Kedei, Dibyangana D. Bhattacharyya, Adelaide L. Wink, Elijah F. Edmondson, Donna Butcher, Andrew C. Warner, Tiffany H. Dorsey, David A. Scheiblin, William Heinz, Richard J. Bryant, Robert J. Kinders, Stanley Lipkowitz, Stephen TC. Wong, Milind Pore, Stephen M. Hewitt, Daniel W. McVicar, Stephen K. Anderson, Jenny Chang, Sharon A. Glynn, Stefan Ambs, Stephen J. Lockett, David A. Wink
Publikováno v:
Redox Biology, Vol 58, Iss , Pp 102529- (2022)
Antitumor immune polarization is a key predictor of clinical outcomes to cancer therapy. An emerging concept influencing clinical outcome involves the spatial location of CD8+ T cells, within the tumor. Our earlier work demonstrated immunosuppressive
Externí odkaz:
https://doaj.org/article/861cead31d3f4ebb8be3e8669adfe0cf
Autor:
Anne C. Gilmore, Sarah J. Flaherty, Veena Somasundaram, David A. Scheiblin, Stephen J. Lockett, David A. Wink, William F. Heinz
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Gilmore et al. describe an in vitro tumorigenesis model that produces cell-generated gradients of oxygen and nutrients. Its 2D configuration simplifies live cell, immunofluorescent, and microscopic interrogation of cancer cell behaviour in differenti
Externí odkaz:
https://doaj.org/article/e13ab04655bc4d119008eaaf1d13d34b
Autor:
Veena Somasundaram, Anne C. Gilmore, Debashree Basudhar, Erika Mariana Palmieri, David A. Scheiblin, William F. Heinz, Robert.Y.S. Cheng, Lisa A. Ridnour, Grégoire Altan-Bonnet, Stephen J. Lockett, Daniel W. McVicar, David A. Wink
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
The role of nitric oxide (NO) in cancer progression has largely been studied in the context of tumor NOS2 expression. However, pro- versus anti-tumor signaling is also affected by tumor cell-macrophage interactions. While these cell-cell interactions
Externí odkaz:
https://doaj.org/article/e9a5ee25069b4219b610c262682be9b9
Publikováno v:
A33. LATE BREAKING ADVANCES IN ASTHMA AND IMMUNOLOGY.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dc081c81c3843b0385cc43d26912778
https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1391
https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1391
Akademický článek
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Autor:
Karlyne M. Reilly, John A. Beutler, David F. Wiemer, Stephen J. Lockett, Claudia A. Lipschultz, Jessica C. Walrath, Robert G. Tuskan, Demirkan B. Gürsel, Thomas J. Turbyville
Neurofibromatosis type 1 (NF1) is the most common genetic disease affecting the nervous system. Patients typically develop many tumors over their lifetime, leading to increased morbidity and mortality. The NF1 gene, mutated in NF1, is also commonly m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a70e91fdd3394001ccb22c31934e7665
https://doi.org/10.1158/1535-7163.c.6531789.v1
https://doi.org/10.1158/1535-7163.c.6531789.v1
Autor:
Karlyne M. Reilly, John A. Beutler, David F. Wiemer, Stephen J. Lockett, Claudia A. Lipschultz, Jessica C. Walrath, Robert G. Tuskan, Demirkan B. Gürsel, Thomas J. Turbyville
Supplementary Data from Schweinfurthin A Selectively Inhibits Proliferation and Rho Signaling in Glioma and Neurofibromatosis Type 1 Tumor Cells in a NF1-GRD–Dependent Manner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e32dacb0d0ff559bb01b60a90cb604
https://doi.org/10.1158/1535-7163.22485129.v1
https://doi.org/10.1158/1535-7163.22485129.v1
Publikováno v:
Cell Migration in Three Dimensions ISBN: 9781071628867
Localization of mRNAs at the front of migrating cells is a widely used mechanism that functionally supports efficient cell movement. It is observed in single cells on two-dimensional surfaces, as well as in multicellular three-dimensional (3D) struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24414e99b6da0f84e453dff8dc8578ff
https://doi.org/10.1007/978-1-0716-2887-4_16
https://doi.org/10.1007/978-1-0716-2887-4_16
Autor:
King John Pascual BA, MAT, Ekaterina Vlasova BA, Kimberly J Lockett MSW, LICSW, Judson Richardson MSW, LICSW, Michael Yochelson MD, MBA
Publikováno v:
Journal of Patient Experience, Vol 5 (2018)
Hallmarks of the difficult period of transition from hospital to home following stroke include stroke survivor and caregiver uncertainty about actionable steps toward recovery and prevention and unfamiliarity with related resources. Current research
Externí odkaz:
https://doaj.org/article/5d157bd190434e5c9706820e1f4e6b86