Zobrazeno 1 - 10
of 664
pro vyhledávání: '"J. Lessard"'
Autor:
Pattarawan Pattamaprapanont, Eileen M. Cooney, Tara L. MacDonald, Joao A. Paulo, Hui Pan, Jonathan M. Dreyfuss, Sarah J. Lessard
Publikováno v:
Matrix Biology Plus, Vol 23, Iss , Pp 100159- (2024)
Skeletal muscle has a unique ability to remodel in response to stimuli such as contraction and aerobic exercise training. Phenotypic changes in muscle that occur with training such as a switch to a more oxidative fiber type, and increased capillary d
Externí odkaz:
https://doaj.org/article/37f49428b788458294966f8f3bd9d9c4
Autor:
Bhuwan Khatri, Kandice L. Tessneer, Astrid Rasmussen, Farhang Aghakhanian, Tove Ragna Reksten, Adam Adler, Ilias Alevizos, Juan-Manuel Anaya, Lara A. Aqrawi, Eva Baecklund, Johan G. Brun, Sara Magnusson Bucher, Maija-Leena Eloranta, Fiona Engelke, Helena Forsblad-d’Elia, Stuart B. Glenn, Daniel Hammenfors, Juliana Imgenberg-Kreuz, Janicke Liaaen Jensen, Svein Joar Auglænd Johnsen, Malin V. Jonsson, Marika Kvarnström, Jennifer A. Kelly, He Li, Thomas Mandl, Javier Martín, Gaétane Nocturne, Katrine Brække Norheim, Øyvind Palm, Kathrine Skarstein, Anna M. Stolarczyk, Kimberly E. Taylor, Maria Teruel, Elke Theander, Swamy Venuturupalli, Daniel J. Wallace, Kiely M. Grundahl, Kimberly S. Hefner, Lida Radfar, David M. Lewis, Donald U. Stone, C. Erick Kaufman, Michael T. Brennan, Joel M. Guthridge, Judith A. James, R. Hal Scofield, Patrick M. Gaffney, Lindsey A. Criswell, Roland Jonsson, Per Eriksson, Simon J. Bowman, Roald Omdal, Lars Rönnblom, Blake Warner, Maureen Rischmueller, Torsten Witte, A. Darise Farris, Xavier Mariette, Marta E. Alarcon-Riquelme, PRECISESADS Clinical Consortium, Caroline H. Shiboski, Sjögren’s International Collaborative Clinical Alliance (SICCA), Marie Wahren-Herlenius, Wan-Fai Ng, UK Primary Sjögren’s Syndrome Registry, Kathy L. Sivils, Indra Adrianto, Gunnel Nordmark, Christopher J. Lessard
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/38d950a26aca41828a73087f5c462f45
Autor:
Bhuwan Khatri, Kandice L. Tessneer, Astrid Rasmussen, Farhang Aghakhanian, Tove Ragna Reksten, Adam Adler, Ilias Alevizos, Juan-Manuel Anaya, Lara A. Aqrawi, Eva Baecklund, Johan G. Brun, Sara Magnusson Bucher, Maija-Leena Eloranta, Fiona Engelke, Helena Forsblad-d’Elia, Stuart B. Glenn, Daniel Hammenfors, Juliana Imgenberg-Kreuz, Janicke Liaaen Jensen, Svein Joar Auglænd Johnsen, Malin V. Jonsson, Marika Kvarnström, Jennifer A. Kelly, He Li, Thomas Mandl, Javier Martín, Gaétane Nocturne, Katrine Brække Norheim, Øyvind Palm, Kathrine Skarstein, Anna M. Stolarczyk, Kimberly E. Taylor, Maria Teruel, Elke Theander, Swamy Venuturupalli, Daniel J. Wallace, Kiely M. Grundahl, Kimberly S. Hefner, Lida Radfar, David M. Lewis, Donald U. Stone, C. Erick Kaufman, Michael T. Brennan, Joel M. Guthridge, Judith A. James, R. Hal Scofield, Patrick M. Gaffney, Lindsey A. Criswell, Roland Jonsson, Per Eriksson, Simon J. Bowman, Roald Omdal, Lars Rönnblom, Blake Warner, Maureen Rischmueller, Torsten Witte, A. Darise Farris, Xavier Mariette, Marta E. Alarcon-Riquelme, PRECISESADS Clinical Consortium, Caroline H. Shiboski, Sjögren’s International Collaborative Clinical Alliance (SICCA), Marie Wahren-Herlenius, Wan-Fai Ng, UK Primary Sjögren’s Syndrome Registry, Kathy L. Sivils, Indra Adrianto, Gunnel Nordmark, Christopher J. Lessard
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The genetic architecture underlying Sjögren’s syndrome is not fully understood. Here, the authors perform a genome-wide association study to identify 10 new genetic risk regions, implicating genes involved in immune and salivary gland function.
Externí odkaz:
https://doaj.org/article/ee17c34d06624822ae2f0ffc7f740171
Autor:
Yiran Shen, Bhuwan Khatri, Santosh Rananaware, Danmeng Li, David A Ostrov, Piyush K Jain, Christopher J Lessard, Cuong Q Nguyen
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0276700 (2023)
COVID-19 is caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). The severity of COVID-19 is highly variable and related to known (e.g., age, obesity, immune deficiency) and unknown risk factors. The widespread clinical symptoms en
Externí odkaz:
https://doaj.org/article/04b5c4c581934edb9ab6936c6ca5c5b7
Autor:
Astrid Rasmussen, Kathy L Sivils, Joel M Guthridge, Judith A James, Jennifer A Kelly, Patrick M Gaffney, Jonathan D Wren, Stuart B Glenn, R Hal Scofield, Christopher J Lessard, Donald U Stone, David M Lewis, Lida Radfar, A Darise Farris, John A Ice, Courtney G Montgomery, Michelle L Joachims, Bhuwan Khatri, Chuang Li, Kandice L Tessneer, Anna M Stolarczyk, Nicolas Means, Kiely M Grundahl, Graham B Wiley, Indra Adrianto
Publikováno v:
RMD Open, Vol 8, Iss 2 (2022)
Objective Sjögren’s disease (SjD) is an autoimmune disease characterised by inflammatory destruction of exocrine glands. Patients with autoantibodies to Ro/SSA (SjDRo+) exhibit more severe disease. Long non-coding RNAs (lncRNAs) are a functionally
Externí odkaz:
https://doaj.org/article/47cfe83cffdf4adfa6b8c72936c25cd6
Autor:
Agnieshka M. Agasing, Qi Wu, Bhuwan Khatri, Nadja Borisow, Klemens Ruprecht, Alexander Ulrich Brandt, Saurabh Gawde, Gaurav Kumar, James L. Quinn, Rose M. Ko, Yang Mao-Draayer, Christopher J. Lessard, Friedemann Paul, Robert C. Axtell
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Type I IFN has apposing effects in neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS). Here the authors perform molecular profiling of NMOSD patients and mouse mechanistic experiments of neuro-inflammation to show that IFN-I s
Externí odkaz:
https://doaj.org/article/7b8aeab093224a3480c864d3e07e1bf6
Autor:
Jamie-Lee M Thompson, Daniel W D West, Thomas M Doering, Boris P Budiono, Sarah J Lessard, Lauren G Koch, Steven L Britton, Nuala M Byrne, Matthew A Brown, Kevin J Ashton, Vernon G Coffey
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0261723 (2022)
Skeletal muscle atrophy is a physiological response to disuse, aging, and disease. We compared changes in muscle mass and the transcriptome profile after short-term immobilization in a divergent model of high and low responders to endurance training
Externí odkaz:
https://doaj.org/article/5f7d11bb94e3436bace2a33a0215c8a7
Autor:
André L. Queiroz, Sarah J. Lessard, Amanda T. Ouchida, Hygor N. Araujo, Dawit A. Gonçalves, Dimitrius Santiago P. Simões Fróes Guimarães, Bruno G. Teodoro, Kawai So, Enilza M. Espreafico, Michael F. Hirshman, Luciane C. Alberici, Isis do Carmo Kettelhut, Laurie J. Goodyear, Leonardo R. Silveira
Publikováno v:
Molecular Metabolism, Vol 51, Iss , Pp 101226- (2021)
Objective: MicroRNAs (miRNA) are known to regulate the expression of genes involved in several physiological processes including metabolism, mitochondrial biogenesis, proliferation, differentiation, and cell death. Methods: Using “in silico” anal
Externí odkaz:
https://doaj.org/article/f16977abeca54a81845fd637f904eadd
Autor:
Bhuwan Khatri, Kandice L. Tessneer, Astrid Rasmussen, Farhang Aghakhanian, Tove Ragna Reksten, Adam Adler, Ilias Alevizos, Juan-Manuel Anaya, Lara A. Aqrawi, Eva Baecklund, Johan G. Brun, Sara Magnusson Bucher, Maija-Leena Eloranta, Fiona Engelke, Helena Forsblad-d’Elia, Stuart B. Glenn, Daniel Hammenfors, Juliana Imgenberg-Kreuz, Janicke Liaaen Jensen, Svein Joar Auglænd Johnsen, Malin V. Jonsson, Marika Kvarnström, Jennifer A. Kelly, He Li, Thomas Mandl, Javier Martín, Gaétane Nocturne, Katrine Brække Norheim, Øyvind Palm, Kathrine Skarstein, Anna M. Stolarczyk, Kimberly E. Taylor, Maria Teruel, Elke Theander, Swamy Venuturupalli, Daniel J. Wallace, Kiely M. Grundahl, Kimberly S. Hefner, Lida Radfar, David M. Lewis, Donald U. Stone, C. Erick Kaufman, Michael T. Brennan, Joel M. Guthridge, Judith A. James, R. Hal Scofield, Patrick M. Gaffney, Lindsey A. Criswell, Roland Jonsson, Per Eriksson, Simon J. Bowman, Roald Omdal, Lars Rönnblom, Blake Warner, Maureen Rischmueller, Torsten Witte, A. Darise Farris, Xavier Mariette, Marta E. Alarcon-Riquelme, PRECISESADS Clinical Consortium, Caroline H. Shiboski, Sjögren’s International Collaborative Clinical Alliance (SICCA), Marie Wahren-Herlenius, Wan-Fai Ng, UK Primary Sjögren’s Syndrome Registry, Kathy L. Sivils, Indra Adrianto, Gunnel Nordmark, Christopher J. Lessard
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/75a032d749534f8d9af7665484459379
Autor:
Astrid Rasmussen, Donald U. Stone, C. Erick Kaufman, Kimberly S. Hefner, Nicole R. Fram, Rhea L. Siatkowski, Andrew J. W. Huang, James Chodosh, Pablo T. Rasmussen, Dustin A. Fife, Nathan Pezant, Kiely Grundahl, Lida Radfar, David M. Lewis, Michael H. Weisman, Swamy Venuturupalli, Daniel J. Wallace, Nelson L. Rhodus, Michael T. Brennan, Courtney G. Montgomery, Christopher J. Lessard, R. Hal Scofield, Kathy L. Sivils
Publikováno v:
ACR Open Rheumatology, Vol 1, Iss 5, Pp 292-302 (2019)
Objective The objective of this study was to assess the performance and reproducibility of the two currently used ocular surface staining scores in the assessment of keratoconjunctivitis sicca in Sjögren syndrome (SS) research classification. Method
Externí odkaz:
https://doaj.org/article/552f7214c8d347e4991947424a1c3f98