Zobrazeno 1 - 10
of 201
pro vyhledávání: '"J. Leenders"'
Autor:
Mariano A. Molina, William P. J. Leenders, Martijn A. Huynen, Willem J. G. Melchers, Karolina M. Andralojc
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Persistent infections with high-risk human papillomavirus (hrHPV) can cause cervical squamous intraepithelial lesions (SIL) that may progress to cancer. The cervicovaginal microbiome (CVM) correlates with SIL, but the temporal com
Externí odkaz:
https://doaj.org/article/38089f5a8b1b4bd9bf3821bd54f9488a
Autor:
Kevin J. J. Kwinten, Victor A. Lemain, Joanne A. deHullu, William P. J. Leenders, Miranda P. Steenbeek, Anne M. vanAltena, Johanna M. A. Pijnenborg
Publikováno v:
Cancer Medicine, Vol 13, Iss 14, Pp n/a-n/a (2024)
Abstract Background In the last decade, technical innovations have resulted in the development of several minimally invasive diagnostic cancer tools. Within women at high risk of developing ovarian cancer (OC) or endometrial cancer (EC) due to a here
Externí odkaz:
https://doaj.org/article/42c9f299d41d45cfbc47677050e7f1a2
Autor:
Mariano A. Molina, Karolina M. Andralojc, Martijn A. Huynen, William P. J. Leenders, Willem J. G. Melchers
Publikováno v:
npj Biofilms and Microbiomes, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract The cervicovaginal microbiome (CVM) correlates with women’s cervical health, and variations in its composition are associated with high-risk human papillomavirus (hrHPV) infection outcomes. Cervicovaginal microbes have been grouped into fi
Externí odkaz:
https://doaj.org/article/8c45809d59ae4820a9ccae834f080dfb
Autor:
Karolina M. Andralojc, Duaa Elmelik, Menno Rasing, Bernard Pater, Albert G. Siebers, Ruud Bekkers, Martijn A. Huynen, Johan Bulten, Diede Loopik, Willem J. G. Melchers, William P. J. Leenders
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background Because most cervical cancers are caused by high-risk human papillomaviruses (hrHPVs), cervical cancer prevention programs increasingly employ hrHPV testing as a primary test. The high sensitivity of HPV tests is accompanied by lo
Externí odkaz:
https://doaj.org/article/2b6b2ae1544840ce822ea691895083a9
Autor:
Karolina M. Andralojc, Mariano A. Molina, Mengjie Qiu, Bram Spruijtenburg, Menno Rasing, Bernard Pater, Martijn A. Huynen, Bas E. Dutilh, Thomas H. A. Ederveen, Duaa Elmelik, Albert G. Siebers, Diede Loopik, Ruud L. M. Bekkers, William P. J. Leenders, Willem J. G. Melchers
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-18 (2021)
Abstract Background The cervicovaginal microbiome (CVM) plays a significant role in women’s cervical health and disease. Microbial alterations at the species level and characteristic community state types (CST) have been associated with acquisition
Externí odkaz:
https://doaj.org/article/a9e97d83932d40de9ec28b0e6c2e6fef
Publikováno v:
BMJ Open, Vol 12, Iss 11 (2022)
Introduction People treated with haemodialysis are at increased risk for all-cause and cardiovascular mortality. Plasma magnesium concentration has been inversely associated with these risks. Therefore, plasma magnesium may be a new modifiable risk f
Externí odkaz:
https://doaj.org/article/72ef34d0dd344f58a28054897076e3fb
Publikováno v:
Frontiers in Psychology, Vol 13 (2022)
Collective intelligence (CI) in organizational teams has been predominantly understood and explained in terms of the quality of the outcomes that the team produces. This manuscript aims to extend the understanding of CI in teams, by disentangling the
Externí odkaz:
https://doaj.org/article/f86fe8d47bc54aaf94422c9182d19270
Autor:
Mariano A. Molina, Britt A. Coenen, William P. J. Leenders, Karolina M. Andralojc, Martijn A. Huynen, Willem J. G. Melchers
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Cervical cancer is the third leading cause of female cancers globally, resulting in more than 300,000 deaths every year. The majority of all cervical cancers are caused by persistent infections with high-risk human papillomaviruses (hrHPV) t
Externí odkaz:
https://doaj.org/article/d351133fdbdc452cb567b31ef98645ea
Autor:
Cristina Aguado, Cristina Teixido, Ruth Román, Roxana Reyes, Ana Giménez‐Capitán, Elba Marin, Carlos Cabrera, Nuria Viñolas, Sergi Castillo, Silvia Muñoz, Ainara Arcocha, Laura López‐Vilaró, Ivana Sullivan, Erika Aldeguer, Sonia Rodríguez, Irene Moya, Santiago Viteri, Andrés Felipe Cardona, Ramon Palmero, Cristina Sainz, Miguel Mesa‐Guzmán, Maria D. Lozano, Andrés Aguilar‐Hernández, Alejandro Martínez‐Bueno, María González‐Cao, Elena Gonzalvo, William P. J. Leenders, Rafael Rosell, Luis M. Montuenga, Aleix Prat, Miguel A. Molina‐Vila, Noemi Reguart
Publikováno v:
Molecular Oncology, Vol 15, Iss 2, Pp 350-363 (2021)
MET inhibitors have shown activity in non‐small‐cell lung cancer patients (NSCLC) with MET amplification and exon 14 skipping (METΔex14). However, patient stratification is imperfect, and thus, response rates have varied widely. Here, we studied
Externí odkaz:
https://doaj.org/article/5db041644f0248ee90bd178c373b1867
Autor:
Tom H. Peeters, Krissie Lenting, Vincent Breukels, Sanne A. M. van Lith, Corina N. A. M. van den Heuvel, Remco Molenaar, Arno van Rooij, Ron Wevers, Paul N. Span, Arend Heerschap, William P. J. Leenders
Publikováno v:
Cancer & Metabolism, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background Mutations in isocitrate dehydrogenase 1 (IDH1) occur in various types of cancer and induce metabolic alterations resulting from the neomorphic activity that causes production of D-2-hydroxyglutarate (D-2-HG) at the expense of α-k
Externí odkaz:
https://doaj.org/article/134a2d6836154e8195617e7ff0cbfff9