Zobrazeno 1 - 10
of 31
pro vyhledávání: '"J. Lee Poyer"'
Publikováno v:
Free Radical Biology and Medicine. 22:843-852
Electron impact (EI) tandem mass spectrometry (MS/MS) combined with EPR spin trapping was used to detect and identify the free radical metabolites of various halocarbons in rat liver microsomal dispersions. EPR spectra of the spin adducts of radical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f2224f7beb6cd35148cc357f42d77ab
https://doi.org/10.1016/s0891-5849(96)00431-5
https://doi.org/10.1016/s0891-5849(96)00431-5
Autor:
Paul Schuler, J. Lee Poyer, Edward G. Janzen, Melinda West, Josphat C. Matasyoh, Hartmut B. Stegmann
Publikováno v:
Magnetic Resonance in Chemistry. 34:351-359
A chiral spin trap, 5,5-dimethyl-3-phenylpyrroline-1-oxide (5), and several hydroxylamines were synthesized. The structures and conformations of these compounds were investigated mainly by 1H NMR spectroscopy. This spin trap was used to trap carbon-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7709b34fe3745fced96f1c92a95f5176
https://doi.org/10.1002/(sici)1097-458x(199605)34:5<351::aid-omr882>3.0.co
https://doi.org/10.1002/(sici)1097-458x(199605)34:5<351::aid-omr882>3.0.co
Publikováno v:
Journal of Biochemical and Biophysical Methods. 30:239-247
To obtain the strongest possible free radical spin adduct signal using the electron paramagnetic resonance spectroscopy-spin trapping technique, it is desirable to load an animal with the highest dose of spin trap possible. One hundred and twenty six
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75836e9ef2101fb886f628a0dc598861
https://doi.org/10.1016/0165-022x(95)00012-1
https://doi.org/10.1016/0165-022x(95)00012-1
Publikováno v:
Journal of the American Society for Mass Spectrometry. 6:847-853
Electron ionization and thermospray were used in conjunction with tandem mass spectrometry methods to identify trichloromethyl/C-phenyl-N-tert-butyl nitrone (PBN) spin adducts produced in rat liver microsomal dispersions that had been treated with re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af1999f1c5182b711d79fd93697ad80a
https://doi.org/10.1016/1044-0305(95)00328-b
https://doi.org/10.1016/1044-0305(95)00328-b
Publikováno v:
Free Radical Research Communications. 9:343-351
Free radicals were detected from the in vitro metabolism of halothane (rat liver microsomes) by the PBN spin trapping method. The detected radical species include the 1-chloro-2,2,2-trifluoro-1-ethyl radical (I), as determined by mass spectral analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca6defeb9c214384f10e51418a602fda
https://doi.org/10.3109/10715769009145693
https://doi.org/10.3109/10715769009145693
Publikováno v:
Free Radical Biology and Medicine. 9:93-99
Considerable progress has been made in the use of spin-trapping agents for the trapping of free radicals in biological systems. Radicals have been detected in both in vitro and in vivo systems using this methodology. Free radicals have not only been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5762a5f1555698cd2eca8e598ed721
https://doi.org/10.1016/0891-5849(90)90110-5
https://doi.org/10.1016/0891-5849(90)90110-5
Publikováno v:
The Journal of Organic Chemistry. 62:1176-1178
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::838cda2f91554b57249c5e2316329ab7
https://doi.org/10.1021/jo961476x
https://doi.org/10.1021/jo961476x
Autor:
J. Lee Poyer, Edward G. Janzen, Rheal A. Towner, Edward K. Lai, Peter H. Krygsman, Paul B. McCay, Gemma Brueggemann
Publikováno v:
Free radical research communications. 9(3-6)
Positive structural identification of the PBN-trichloromethyl spin adduct in vitro was accomplished with the use of high pressure liquid chromatography and/or gas chromatography coupled with mass spectrometry. Both thin layer and liquid chromatograph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c45eb593095f903878bccad288cd29
https://pubmed.ncbi.nlm.nih.gov/2167273
https://pubmed.ncbi.nlm.nih.gov/2167273
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 2. :1183
In this paper, the spin trap C-phenyl N-tert-butyl nitrone (PBN) is reported to react with cyanohalocarbons (CCl3CN, CHCl2CN, CHBr2CN and CH2BrCN) in a molecular reaction. Some 1:1 molecular adducts are produced in these reactions at room temperature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fef13b09940a39a2194ecac5463886d9
https://doi.org/10.1039/p29960001183
https://doi.org/10.1039/p29960001183
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 2. :1985
The toxic gas phosgene reacts with the spin trap C-phenyl N-tert-butyl nitrone (PBN) to produce spontaneously N-tert-butyl-N-chloroacylaminoxyl as the main radical product identified by EPR and mass spectrometry. The reaction mechanisms for the forma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee11b824c2d08b48015c1503495539e8
https://doi.org/10.1039/p29960001985
https://doi.org/10.1039/p29960001985