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The novel function of the Saccharomyces cerevisiaeCBP2 gene as a splicing factor essential to excision of the Saccharomyces douglasiiLSU intron in vivo

Autor: P. P. Slonimski, J. Lazowska, G.-Y. Li, G.-L. Tian

Publikováno v: Molecular and General Genetics MGG. 258:60-68

In the yeast Saccharomyces cerevisiae, the product of the nuclear gene CBP2 is required exclusively for the splicing of the terminal intron of the mitochondrial cytochrome b gene. The homologous gene from the related yeast, Saccharomyces douglasii, h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a606250735e4606a1d43428e15116a89
https://doi.org/10.1007/s004380050707

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Physical and genetic organization of Petite and Grande yeast mitochondrial DNA. III. High resolution melting and reassociation studies

Autor: F, Michel, J, Lazowska, G, Faye, H, Fukuhara, P P, Slonimski

Publikováno v: Journal of molecular biology. 85(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::78dac56c15888a1bcb9f6eb670803bd6
https://pubmed.ncbi.nlm.nih.gov/22003574

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Physical and genetic organization of Petite and Grande yeast mitochondrial DNA. II. DNA-DNA hybridization studies and buoyant density determinations

Autor: J, Lazowska, F, Michel, G, Faye, H, Fukuhara, P P, Slonimski

Publikováno v: Journal of molecular biology. 85(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1ff18b758a8953ec18a455b53c9eb832
https://pubmed.ncbi.nlm.nih.gov/22003573

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NAM9 nuclear suppressor of mitochondrial ochre mutations in Saccharomyces cerevisiae codes for a protein homologous to S4 ribosomal proteins from chloroplasts, bacteria, and eucaryotes

Autor: Barbara Szczesniak, K Wrobel, Magdalena Boguta, P Borsuk, Anna Kruszewska, A Dmochowska, J Lazowska, P P Slonimski, A Gargouri

Publikováno v: Molecular and Cellular Biology. 12:402-412

We report the genetic characterization, molecular cloning, and sequencing of a novel nuclear suppressor, the NAM9 gene from Saccharomyces cerevisiae, which acts on mutations of mitochondrial DNA. The strain NAM9-1 was isolated as a respiration-compet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35576f4f3967d61318c7cc5c208b0f30
https://doi.org/10.1128/mcb.12.1.402

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Enhanced expression of the DNA damage-inducible gene DIN7 results in increased mutagenesis of mitochondrial DNA in Saccharomyces cerevisiae

Autor: Piotr Koprowski, M. U. Fikus, J. Lazowska, Piotr Dzierzbicki, Zygmunt Ciesla, Piotr A. Mieczkowski

Publikováno v: Molecular genetics and genomics : MGG. 269(5)

We reported previously that the product of DIN7, a DNA damage-inducible gene of Saccharomyces cerevisiae, belongs to the XPG family of proteins, which are involved in DNA repair and replication. This family includes the S. cerevisiae protein Rad2p an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ef0510554ce5a2e47992a27d08d712
https://pubmed.ncbi.nlm.nih.gov/12827502

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A novel nuclear gene, CBT1, essential for mitochondrial cytochrome b formation: terminal processing of mRNA and intron dependence

Autor: K J, Rieger, G, Aljinovic, J, Lazowska, T M, Pohl, P P, Slonimski

Publikováno v: Current genetics. 32(3)

We describe a new nuclear gene, CBT1 (Cytochrome B Termination), specifically involved in the generation of mature mRNA of cytochrome b in yeast mitochondria. Disruption of CBT1 (corresponding to ORF YKL 208W) results in a respiratory deficiency (no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6f1ecdde2c8950559f96a6377ed2d6
https://pubmed.ncbi.nlm.nih.gov/9339340

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Replacement of two non-adjacent amino acids in the S.cerevisiae bi2 intron-encoded RNA maturase is sufficient to gain a homing-endonuclease activity

Autor: T, Szczepanek, J, Lazowska

Publikováno v: The EMBO journal. 15(14)

Two homologous group I introns, the second intron of the cyt b gene, from related Saccharomyces species differ in their mobility. The S.capensis intron is mobile and encodes the I-ScaI endonuclease promoting intron homing, whilst the homologous S.cer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::354a2b423bbf584e3dc88ccb4f02d880
https://pubmed.ncbi.nlm.nih.gov/8670880

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Incipient mitochondrial evolution in yeasts. II. The complete sequence of the gene coding for cytochrome b in Saccharomyces douglasii reveals the presence of both new and conserved introns and discloses major differences in the fixation of mutations in evolution

Autor: G L, Tian, F, Michel, C, Macadre, P P, Slonimski, J, Lazowska

Publikováno v: Journal of molecular biology. 218(4)

We have determined the complete sequence of the mitochondrial gene coding for cytochrome b in Saccharomyces douglasii. The gene is 6310 base-pairs long and is interrupted by four introns. The first one (1311 base-pairs) belongs to the group ID of sec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b642a3c9dc2341831c2a54be382e2263
https://pubmed.ncbi.nlm.nih.gov/1708831

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A new specific DNA endonuclease activity in yeast mitochondria

Autor: J. Lazowska, G.-L. Tian, A. Delahodde, D Hatat, Claude Jacq, Bruno Sargueil

Publikováno v: Molecular and General Genetics MGG. 225:340-341

Two group I intron-encoded proteins from the yeast mitochondrial genome have already been shown to have a specific DNA endonuclease activity. This activity mediates intron insertion by cleaving the DNA sequence corresponding to the splice junction of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c903866a88218379d7d52e7ee3e2ed
https://doi.org/10.1007/bf00269867

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