Zobrazeno 1 - 10
of 323
pro vyhledávání: '"J. LaFontaine"'
Autor:
Isabel S. Naarmann-de Vries, Christiane Zorbas, Amina Lemsara, Michael Piechotta, Felix G. M. Ernst, Ludivine Wacheul, Denis L. J. Lafontaine, Christoph Dieterich
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 652-665 (2023)
Ribosomal RNAs are decorated by numerous post-transcriptional modifications whose exact roles in ribosome biogenesis, function, and human pathophysiology remain largely unknown. Here, we report a targeted direct rRNA sequencing approach involving a s
Externí odkaz:
https://doaj.org/article/8f77b1764996404daaed691a7f7b7d25
Autor:
Benjamin Cappe, Mike Vadi, Eliza Sack, Ludivine Wacheul, Bruno Verstraeten, Sara Dufour, Julien Franck, Wei Xie, Francis Impens, An Hendrix, Denis L. J. Lafontaine, Peter Vandenabeele, Franck B. Riquet
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 10, Pp n/a-n/a (2023)
Abstract Formation of extracellular vesicles (EVs) has emerged as a novel paradigm in cell‐to‐cell communication in health and disease. EVs are notably produced during cell death but it had remained unclear whether different modalities of regulat
Externí odkaz:
https://doaj.org/article/9dc0577ed1854c459bb1f2a86e8e4fdb
Autor:
Melvin Pan, Christiane Zorbas, Maki Sugaya, Kensuke Ishiguro, Miki Kato, Miyuki Nishida, Hai-Feng Zhang, Marco M. Candeias, Akimitsu Okamoto, Takamasa Ishikawa, Tomoyoshi Soga, Hiroyuki Aburatani, Juro Sakai, Yoshihiro Matsumura, Tsutomu Suzuki, Christopher G. Proud, Denis L. J. Lafontaine, Tsuyoshi Osawa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Small molecules that target RNA Polymerase I inhibit ribosome biogenesis to activate p53 through the nucleolar surveillance response pathway. Here, the authors show that p53 induction by ribosome stress is dependent on extracellular glutamine availab
Externí odkaz:
https://doaj.org/article/5a2c48021da748188909409721466a55
Autor:
Aynur Sönmez, Rasem Mustafa, Salome T. Ryll, Francesca Tuorto, Ludivine Wacheul, Donatella Ponti, Christian Litke, Tanja Hering, Kerstin Kojer, Jenniver Koch, Claudia Pitzer, Joachim Kirsch, Andreas Neueder, Grzegorz Kreiner, Denis L. J. Lafontaine, Michael Orth, Birgit Liss, Rosanna Parlato
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-12 (2021)
Abstract Transcriptional and cellular-stress surveillance deficits are hallmarks of Huntington’s disease (HD), a fatal autosomal-dominant neurodegenerative disorder caused by a pathological expansion of CAG repeats in the Huntingtin (HTT) gene. The
Externí odkaz:
https://doaj.org/article/ef5389a9059145348fc5353ee8922ca1
Autor:
Amandine Duchemin, Tina O’Grady, Sarah Hanache, Agnès Mereau, Marc Thiry, Ludivine Wacheul, Catherine Michaux, Eric Perpète, Eric Hervouet, Paul Peixoto, Felix G. M. Ernst, Yann Audic, Franck Dequiedt, Denis L. J. Lafontaine, Denis Mottet
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
In yeast, TFIP11 and DHX15 promote the disassembly of spliceosome complex after splicing is completed. Here the authors show that human TFIP11 functions independently of DHX15 and is required for U6 snRNA 2’-O-methylation and U4/U6.U5 tri-snRNP ass
Externí odkaz:
https://doaj.org/article/93d4369760d94698a2204e30cd575392
Autor:
Jonathan Delhermite, Lionel Tafforeau, Sunny Sharma, Virginie Marchand, Ludivine Wacheul, Ruben Lattuca, Simon Desiderio, Yuri Motorin, Eric Bellefroid, Denis L J Lafontaine
Publikováno v:
PLoS Genetics, Vol 18, Iss 1, p e1010012 (2022)
Ribosomes are essential nanomachines responsible for protein production. Although ribosomes are present in every living cell, ribosome biogenesis dysfunction diseases, called ribosomopathies, impact particular tissues specifically. Here, we evaluate
Externí odkaz:
https://doaj.org/article/3d415ccefde94a13a897dc588394fa83
Autor:
Isaac Planas-Sitjà, Jean-Louis Deneubourg, Denis L. J. Lafontaine, Ludivine Wacheul, Adam L. Cronin
Publikováno v:
Animals, Vol 12, Iss 18, p 2354 (2022)
Consistent inter-individual variation in the propensity to perform different tasks (animal personality) can contribute significantly to the success of group-living organisms. The distribution of different personalities in a group influences collectiv
Externí odkaz:
https://doaj.org/article/50bc9c9d77cf453f8a80ede0a779e340
Autor:
Veronique Mathieu, Breana Laguera, Marco Masi, Sara Adriana Dulanto, Tanner W. Bingham, Lucas W. Hernandez, David Sarlah, Antonio Evidente, Denis L. J. Lafontaine, Alexander Kornienko, Michelle A. Lane
Publikováno v:
Biomolecules, Vol 12, Iss 9, p 1267 (2022)
Alkaloids isolated from members of the Amaryllidaceae plant family are promising anticancer agents. The purpose of the current study was to determine if the isocarbostyrils narciclasine, pancratistatin, lycorane, lycorine, crinane, and haemanthamine
Externí odkaz:
https://doaj.org/article/b9b5ab1ef3e34de6aeefbfe47a867b39
Autor:
Jessee Tinslay, Marc Fournier, Isabelle Couture, Pierre J. Lafontaine, Maxime Lefebvre, Eric Lucas
Publikováno v:
Insects, Vol 13, Iss 5, p 465 (2022)
The striped cucumber beetle (SCB) Acalymma vittatum (F.) (Coleptera: Chrysomelidae) is a prime problem in North American cucurbit crops. While certain chemical pesticides efficiently control SCB in conventional cucurbit fields, alternative solutions
Externí odkaz:
https://doaj.org/article/dfebeec2b14a423faea6a80f60ccf4da
Autor:
Clemens Heissenberger, Jarod A Rollins, Teresa L Krammer, Fabian Nagelreiter, Isabella Stocker, Ludivine Wacheul, Anton Shpylovyi, Koray Tav, Santina Snow, Johannes Grillari, Aric N Rogers, Denis L J Lafontaine, Markus Schosserer
Publikováno v:
eLife, Vol 9 (2020)
Our knowledge about the repertoire of ribosomal RNA modifications and the enzymes responsible for installing them is constantly expanding. Previously, we reported that NSUN-5 is responsible for depositing m5C at position C2381 on the 26S rRNA in Caen
Externí odkaz:
https://doaj.org/article/1cc8244758b2472cba30eb6282f5295a