Výsledky vyhledávání - "J. L. Vancott"

Evidence for CD8+ T-cell immunity to murine rotavirus in the absence of perforin, fas, and gamma interferon

Autor: J L VanCott, Lusijah Rott, J R McGhee, Harry B. Greenberg, C Tin, Manuel A. Franco

Publikováno v: Journal of Virology. 71:479-486

We recently showed that class I-restricted CD8+ T cells mediate clearance of primary rotavirus infection in mice: JHD knockout (JHD -/-) (B-cell-deficient) mice depleted of CD8+ T cells become chronically infected with murine rotavirus, and beta2 mic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f994c77310f07d4c57cb70918eabf7
https://doi.org/10.1128/jvi.71.1.479-486.1997

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Enumeration of isotype-specific antibody-secreting cells derived from gnotobiotic piglets inoculated with porcine rotaviruses

Autor: Wei-Kang Chen, J L VanCott, Thomas Campbell, Linda J. Saif

Publikováno v: Veterinary Immunology and Immunopathology

In order to evaluate mucosal antibody responses to rotavirus, an enzyme-linked immunospot (ELISPOT) assay was adapted to enumerate antibody-secreting cells (ASC) in the mesenteric lymph nodes (MLN), lamina propria (LP) of the small intestine and sple

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fdac7a96b39c808468a1ef38789de09

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Contribution of antibody-secreting cells induced in mucosal lymphoid tissues of pigs inoculated with respiratory or enteric strains of coronavirus to immunity against enteric coronavirus challenge

Autor: J L VanCott, T A Brim, J K Lunney, L J Saif

Publikováno v: The Journal of Immunology. 152:3980-3990

Two antigenically related porcine coronaviruses, transmissible gastroenteritis virus (TGEV) which infects primarily the intestinal tract and causes severe diarrhea, and porcine respiratory coronavirus (PRCV) which infects the respiratory tract and ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::784ade6162412e262033e255764e152d
https://doi.org/10.4049/jimmunol.152.8.3980

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Measurement of HIV-1 Specific and Total Antibody Secreting Cells by ELISPOT

Autor: F W, van Ginkel, J L, Vancott, R, Kaminski, T C, Vancott

Publikováno v: Methods in molecular medicine. 17

B-cells play an important role in protection against pathogens, and they secrete specific antibodies in serum and mucosal secretions upon antigenic stimulation contributing to immune exclusion and clearance of pathogens. The frequency of antibody for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c9423c746f68a18aaac37a7738bd3a22
https://pubmed.ncbi.nlm.nih.gov/21380680

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Role for T cell-independent B cell activity in the resolution of primary rotavirus infection in mice

Autor: J L, VanCott, M M, McNeal, J, Flint, S A, Bailey, A H, Choi, R L, Ward

Publikováno v: European journal of immunology. 31(11)

We examined the importance of T cell-independent B cell activity in the resolution of primary murine (EDIM) rotavirus infection in adult mice. We showed that Rag 1 (C57BL / 6 background) and Rag 2 (BALB / c background) knockout mice, which lack both

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e2be168231b28dcb2475b6a014f50432
https://pubmed.ncbi.nlm.nih.gov/11745356

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Lack of orally induced systemic unresponsiveness in IFN-gamma knockout mice

Autor: M N, Kweon, K, Fujihashi, J L, VanCott, K, Higuchi, M, Yamamoto, J R, McGhee, H, Kiyono

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 160(4)

Splenic T cells isolated from BALB/c mice that had been mucosally tolerized by oral administration of 25 mg of OVA revealed selective increases in IFN-gamma production with impaired levels of IL-2, IL-4, IL-5, and IL-10. These mice possessed reduced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a413e510fb36457c8f890fca4fd4d793
https://pubmed.ncbi.nlm.nih.gov/9469425

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Regulation of mucosal and systemic antibody responses by T helper cell subsets, macrophages, and derived cytokines following oral immunization with live recombinant Salmonella

Autor: J L, VanCott, H F, Staats, D W, Pascual, M, Roberts, S N, Chatfield, M, Yamamoto, M, Coste, P B, Carter, H, Kiyono, J R, McGhee

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 156(4)

We have assessed regulatory Th cell and cytokine responses in mice after oral immunization with recombinant Salmonella (BRD 847) expressing fragment C of tetanus toxoid, since little information is available to explain how these vectors induce mucosa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::27af91bea96ea8b4d4ba6d3e9d9df245
https://pubmed.ncbi.nlm.nih.gov/8568254

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Immune responses to novel Escherichia coli and Salmonella typhimurium vectors that express colonization factor antigen I (CFA/I) of enterotoxigenic E. coli in the absence of the CFA/I positive regulator cfaR

Autor: J. R. Mcghee, David M. Hone, Myron M. Levine, D R Maneval, David W. Pascual, J. L. Vancott, Shaoguang Wu

Publikováno v: Infection and immunity. 63(12)

An asd-stabilized plasmid carrying enterotoxigenic Escherichia coli cfaABCE genes was constructed and called pJGX15C-asd+. Expression of colonization factor antigen I (CFA/I) by this plasmid occurs independently of the cfaABCE positive regulator cfaR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d464f5bfa35bb37bea9229246907dbf9
https://pubmed.ncbi.nlm.nih.gov/7591160

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Cellular immune responses of pigs after primary inoculation with porcine respiratory coronavirus or transmissible gastroenteritis virus and challenge with transmissible gastroenteritis virus

Autor: Theresa A. Brim, Linda J. Saif, Joan K. Lunney, J L VanCott

Publikováno v: Veterinary Immunology and Immunopathology

The contribution of cell-mediated immunity to protective immunity against virulent transmissible gastroenteritis virus (TGEV) infection conferred by primary porcine respiratory coronavirus (PRCV) or TGEV exposure was assessed in pigs that were challe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0339f4a94e0a1f8b5dd9a7b7f50539a1
https://pubmed.ncbi.nlm.nih.gov/8533315

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