Zobrazeno 1 - 10
of 11
pro vyhledávání: '"J. L. Tymoczko"'
Publikováno v:
Molecular Endocrinology. 2:952-958
We have reported that the 7-8S form of the rat liver glucocorticoid receptor is associated with RNA. Whether the unactivated 9-10S form of the glucorticoid receptor is also associated with RNA is less clear. Here we provide evidence that the unactiva
Publikováno v:
Nature New Biology. 241:211-213
IT is currently believed that the action of a steroid hormone is dependent on its binding to a specific cytoplasmic “receptor” protein. The steroid-“receptor” complex then enters the cell nucleus and presumably regulates certain nuclear activ
Publikováno v:
Current topics in molecular endocrinology. 4
Publikováno v:
Steroid Hormone Action and Cancer ISBN: 9781468426038
Studies during the last several years have indicated that androgen action in the rat ventral prostate is dependent on the formation of a specific 5α-dihydrotestosterone-receptor complex, while in some target tissues, testosterone rather than 5α-dih
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8db41f910ca8c8c42fa4711de0fd317f
https://doi.org/10.1007/978-1-4684-2601-4_12
https://doi.org/10.1007/978-1-4684-2601-4_12
Publikováno v:
The Journal of biological chemistry. 255(12)
Publisher Summary This chapter presents androgen receptor interactions in target cells. The prostate cell nuclei of castrated rats contain very few proteins that can bind steroid hormones—including 5α-dihydrotestosterone'specifically and tightly.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55bbf942f7f53bb39a8df9594757c260
https://doi.org/10.1016/b978-0-12-526302-3.50011-3
https://doi.org/10.1016/b978-0-12-526302-3.50011-3
Publikováno v:
Vitamins and hormones. 33
Autor:
J L, Tymoczko, S, Liao
Publikováno v:
Journal of reproduction and fertility. Supplement.
In the rat ventral prostate, various antiandrogens can interfere with the normal formation of an androgen-receptor complex which appears to be required for androgen action. Some of the antagonists may act by inhibiting the enzymatic formation of 5 al
Publikováno v:
The Biochemical journal. 256(1)
We have identified a factor from rat liver cytosol that enhances the DNA-cellulose-binding ability of the glucocorticoid receptor and lowers the sedimentation value from 9-10 S to 4-5 S. Cytosol is prepared in the presence of molybdate, and unactivat
Publikováno v:
Journal of steroid biochemistry. 3(3)
5α-Dihydrotestosterone can bind to specific receptor protein(s) in the microsomal or cytosol fractions of rat ventral prostate. The binding is highly steroid specific and correlated with the androgenicity of the steroids. A large part of the androge