Zobrazeno 1 - 10
of 10
pro vyhledávání: '"J. L. Rutkowski"'
Autor:
Peter Marynen, Hilde Brems, Conxi Lázaro, Maurizio Clementi, S Mason, Eric Legius, Xavier Estivill, J L Rutkowski, C Lopez Correa
Publikováno v:
Human Mutation. 14:387-393
Neurofibromatosis type 1 (NF1) is a common autosomal dominant disorder characterized by a marked variability in expression. A more severe phenotype is frequently observed in the group of patients carrying a large NF1 deletion. To study the extent of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1655ac363ef4400226a49c78df85a636
https://doi.org/10.1002/(sici)1098-1004(199911)14:5<387::aid-humu4>3.0.co
https://doi.org/10.1002/(sici)1098-1004(199911)14:5<387::aid-humu4>3.0.co
Autor:
A. A. Sima, T. Wrone-Smith, A. Merry, Galen B. Toews, Laurence A. Turka, R. S. Mitra, J. L. Rutkowski, Richard E Goodman, Robert M. Strieter, B. J. Nickoloff
Publikováno v:
Molecular Medicine. 1:690-699
BACKGROUND: The nervous system has been implicated in several inflammatory skin disorders based on evidence such as the role of stress in inducing lesions, symmetry of lesions, and sparing of denervated skin. Interleukin 12 (IL-12) is a cytokine rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efcf95a41c6a0ebc87fe1760472f5f78
https://doi.org/10.1007/bf03401609
https://doi.org/10.1007/bf03401609
Publikováno v:
Journal of Neuroscience Research. 36:216-223
Neurofibromin, the product of the neurofibromatosis type 1 (NF1) gene, is a ∼250 kDa protein expressed predominantly in cortical neurons and oligodendrocytes in the central nervous system (CNS) and sensory neurons and Schwann cells in the periphera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b56e90882960a96b2984021fefc0db5d
https://doi.org/10.1002/jnr.490360212
https://doi.org/10.1002/jnr.490360212
Publikováno v:
Medical and pediatric oncology. 35(6)
Neuroblastomas are biologically heterogeneous tumors that consist of two main cell populations: neuroblastic/ganglionic cells and Schwann cells. The amount of Schwannian stroma strongly impacts prognosis. Low tumor vascularity, localized stage, and f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a63c7b83aa3dcf7e2972150b9d38dea
https://pubmed.ncbi.nlm.nih.gov/11107124
https://pubmed.ncbi.nlm.nih.gov/11107124
Publikováno v:
Cancer research. 60(21)
Neuroblastomas are biologically heterogeneous tumors that consist of two main cell populations: neuroblastic/ganglionic cells and Schwann cells. The amount of Schwannian stroma strongly impacts prognosis, and favorable outcome is associated with tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::00d743a9b75cf427338604582fddae6f
https://pubmed.ncbi.nlm.nih.gov/11085514
https://pubmed.ncbi.nlm.nih.gov/11085514
Publikováno v:
Genes, chromosomescancer. 26(4)
We have analyzed 98.5% of the coding region of the NF1 gene at the cDNA level in seven NF1 patients who developed malignant peripheral nerve sheath tumors. Seven germline mutations were detected in six individuals: a 6-bp in-frame deletion in exon 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a2c173d6c3855197019bf3c0412bf17
https://pubmed.ncbi.nlm.nih.gov/10534774
https://pubmed.ncbi.nlm.nih.gov/10534774
Publikováno v:
Cancer research. 58(20)
Neuroblastomas are histopathologically heterogeneous, ranging from immature malignant tumors to benign ganglioneuromas. The amount of Schwann cell stroma greatly increases with neuroblastoma differentiation, and these Schwann cells appear to be norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42eacfba3692fd26dd126eff2554b7ee
https://pubmed.ncbi.nlm.nih.gov/9788610
https://pubmed.ncbi.nlm.nih.gov/9788610
Publikováno v:
Neoplastic Transformation in Human Cell Culture ISBN: 9781461267508
Schwann cells, which arise from the neuroepithelium, are glial cells of the vertebrate peripheral nervous system. During development, they grow along nerve axons and eventually ensheathe or myelinate them. In the genetic disease neurofibromatosis, tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9204426a984bf027c81ae10f638a0d4b
https://doi.org/10.1007/978-1-4612-0411-4_34
https://doi.org/10.1007/978-1-4612-0411-4_34
Autor:
Gihan I. Tennekoon, J. Bigbee, G. M. McKhann, J. Yoshino, Y. Kishimoto, K. W.C. Peden, G. H. DeVries, J. L. Rutkowski
Publikováno v:
The Journal of Cell Biology
Secondary cultures of Schwann cells were transfected with a plasmid containing the SV-40 T antigen gene expressed under the control of the mouse metallothionein-I promoter. We used the calcium phosphate method for transfection and obtained a transfec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3af91ba57eacf1b7a264464e02ae912
http://europepmc.org/articles/PMC2114872
http://europepmc.org/articles/PMC2114872
Publikováno v:
Scopus-Elsevier
Neurofibromatosis type 1 (NF1) is a common inherited cancer predisposition syndrome. The NF1 gene product, neurofibromin, is hypothesized to function as a tumor suppressor and nearly all NF1 patients develop benign peripheral nerve tumors. These neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9c3d04569c2ce2387123e44fbc4ff9a
http://www.scopus.com/inward/record.url?eid=2-s2.0-0034639937&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0034639937&partnerID=MN8TOARS